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Condition: Obesity
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Total 2966 results found since Jan 2013.

Factors associated with residual apnea-hypopnea index variability during continuous positive airway pressure treatment
Chest. 2023 Jan 12:S0012-3692(23)00040-5. doi: 10.1016/j.chest.2022.12.048. Online ahead of print.ABSTRACTBACKGROUND: Continuous positive airway pressure (CPAP) is the first-line therapy for obstructive sleep apnea (OSA). A high or variable residual apnea-hypopnea index (rAHI) reflects treatment failure and is potentially triggered by exacerbation of cardiovascular comorbidities. Previous studies showed that high rAHI and large rAHI variability are associated with underlying comorbidities, OSA characteristics at diagnosis, and CPAP equipment including mask type and settings.RESEARCH QUESTION: What are the factors associate...
Source: Chest - January 15, 2023 Category: Respiratory Medicine Authors: Ana ïs Rossetto Alphanie Midelet S ébastien Baillieul Renaud Tamisier Jean-Christian Borel Arnaud Prigent S ébastien Bailly Jean-Louis P épin Source Type: research

Incretin-based therapy of metabolic disease
Dan Med J. 2022 Dec 21;70(1):A10220597.ABSTRACTRecent studies show that incretin hormone analogues effectively control blood glucose while producing major weight losses and reducing the risk of all-cause mortality, myocardial infarction, stroke and kidney function impairment. Furthermore, the risk of dementia and cognitive impairment is reduced. A monomolecular coagonist (tirzepatide) of receptors for both incretin hormones (glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide) produced HbA1c values below 5.7% in 50% of the treated patients and weight losses exceeding 20% in obese individuals. These new...
Source: Danish Medical Journal - January 11, 2023 Category: General Medicine Authors: Jens Juul Holst Source Type: research