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Condition: Cholesterol
Procedure: Ultrasound

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Total 140 results found since Jan 2013.

Statins and Clinical Outcomes in Patients With Low to Moderate Risk but With Non-obstructive Carotid Plaques: The SCOPE-CP Study
CONCLUSIONS: Benefit of statin therapy was likely to be limited in low to moderate risk patients with carotid plaques. These results could guide physicians in clinical decision-making regarding cardiovascular prevention.PMID:36478652 | PMC:PMC9742388 | DOI:10.4070/kcj.2022.0154
Source: Korean Circulation Journal - December 8, 2022 Category: Cardiology Authors: Minjae Yoon Chan Joo Lee Sungha Park Sang-Hak Lee Source Type: research

Diabetic retinopathy predicts cardiovascular disease independently of subclinical atherosclerosis in individuals with type 2 diabetes: A prospective cohort study
CONCLUSION: DR is a strong predictor of cardiovascular events in T2D individuals at primary CVD prevention, even after accounting for the presence of preclinical carotid atherosclerosis. These results may help to individualize CVD prevention strategies in T2D.PMID:36407461 | PMC:PMC9668891 | DOI:10.3389/fcvm.2022.945421
Source: Atherosclerosis - November 21, 2022 Category: Cardiology Authors: Esmeralda Castelblanco Minerva Granado-Casas Marta Hern ández Montserrat Pinyol Eudald Correig Josep Julve Marina Idalia Rojo-L ópez N úria Alonso Angelo Avogaro Emilio Ortega Didac Mauricio Source Type: research

Non-traditional lipid parameters as potential predictors of carotid plaque vulnerability and stenosis in patients with acute ischemic stroke
CONCLUSION: This study provides evidence that non-traditional lipid parameters (LP-C, non-HDL-C/HDL-C, non-HDL-C, CRI-I, and CRI-II) were potential predictors of carotid plaque vulnerability in patients with AIS. However, no significant correlation was observed between TG/HDL-C and AIP. RLP-C, non-HDL-C/HDL-C, non-HDL-C, TG/HDL-C, CRI-I, CRI-II, and AIP were closely related to the degree of carotid plaque stenosis. Non-traditional lipid parameters can be used as novel biomarkers of carotid plaque vulnerability and stenosis.PMID:36301362 | DOI:10.1007/s10072-022-06472-3
Source: Atherosclerosis - October 27, 2022 Category: Cardiology Authors: Zhao Zhao Huanru Wang Qian Hou Youting Zhou Yanchun Zhang Source Type: research

A narrative review on the application of high-intensity focused ultrasound for the treatment of occlusive and thrombotic arterial disease
CONCLUSIONS: In current preclinical and clinical data, the safety and efficacy of HIFU shows great promise in the treatment of atherosclerotic arterial disease. Future focused studies are warranted to guide the refinement of HIFU settings for more widespread adoption of this technology.PMID:36276806 | PMC:PMC9579503 | DOI:10.1016/j.jvssci.2022.08.001
Source: Atherosclerosis - October 24, 2022 Category: Cardiology Authors: Anand Brahmandam Shin Mei Chan Alan Dardik Naiem Nassiri Edouard Aboian Source Type: research

Carotid contrast-enhanced ultrasonography combined with sirtuin-3 in the diagnosis of plaques in carotid atherosclerosis
CONCLUSIONS: A low expression of SIRT3 predicted a higher risk for unstable plaques in CAS patients. The combination of CEUS and SIRT3 is a potential strategy for diagnosing unstable plaques.PMID:36083252 | DOI:10.17219/acem/152471
Source: Atherosclerosis - September 9, 2022 Category: Cardiology Authors: Aiyun Zhou Wan Zhu Pan Xu Chunxiao Zhao Liping Jiang Wenxin Yuan Source Type: research

Assessment of atherosclerosis in ischemic stroke by means of ultrasound of extracranial/intracranial circulation and serum, urine, and tissue biomarkers
Curr Med Chem. 2022 Aug 17. doi: 10.2174/0929867329666220817123442. Online ahead of print.ABSTRACTIt is a common practice to take into consideration: age, diabetes, smoking, treated and untreated systolic blood pressure, total cholesterol, high-density lipoprotein cholesterol for the prediction of atherosclerosis and stroke. There are, however, ultrasound markers in use for the assessment of atherosclerosis and the evaluation of stroke risk. Two areas of investigation are of interest: the carotid artery and the intracranial arterial circulation. Again, within the domain of the carotid artery, two ultrasonic markers have at...
Source: Atherosclerosis - August 18, 2022 Category: Cardiology Authors: Grigorios G Dimas Maria Zilakaki Argyrios Giannopoulos Stylianos Daios Nikolaos Kakaletsis Georgia Kaiafa Triantafyllos Didangelos Christos Savopoulos Kyriakos Ktenidis Thomas Tegos Source Type: research

Targeted Plasma Proteomics to Predict the Development of Carotid Plaques
CONCLUSIONS: A new set of circulating proteins have been identified that may be considered as markers of preclinical atherosclerosis development. The difference of the protein identified to predict SCA versus IMT progression may reflect different etiological factors.PMID:35775410 | DOI:10.1161/STROKEAHA.122.038887
Source: Atherosclerosis - July 1, 2022 Category: Cardiology Authors: Andrea Baragetti Elisa Mattavelli Liliana Grigore Fabio Pellegatta Paolo Magni Alberico Luigi Catapano Source Type: research

An Ultrasound-Responsive Theranostic Cyclodextrin-Loaded Nanoparticle for Multimodal Imaging and Therapy for Atherosclerosis
This study reports CD delivery via air-trapped polybutylcyanoacrylate nanoparticles (with diameters of 388 ± 34 nm) loaded with CD (CDNPs). The multimodal contrast ability of these nanoparticles after being loaded with IR780 dye in mice is demonstrated using ultrasound and near-infrared imaging. It is shown that CDNPs enhance the cellular uptake of CD in murine cells. In an ApoE-/- mouse model of atherosclerosis, treatment with CDNPs significantly improves the anti-atherosclerotic efficacy of CD. Ultrasound triggering further improves CD uptake, highlighting that CDNPs can be used for ultrasound imaging and ultrasound-res...
Source: Atherosclerosis - June 17, 2022 Category: Cardiology Authors: Sourabh Mehta Viktoria Bongcaron Tien K Nguyen Yugandhara Jirwanka Ana Maluenda Aidan P G Walsh Jathushan Palasubramaniam Mark D Hulett Rohit Srivastava Alex Bobik Xiaowei Wang Karlheinz Peter Source Type: research