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Lifestyle Interventions to Prevent Cardiovascular Events After Stroke and Transient Ischemic Attack Clinical Sciences
Conclusions—We found that lifestyle interventions are effective in lowering systolic blood pressure. About other end points, this systematic review found no effect of lifestyle interventions on cardiovascular event rate mortality, diastolic blood pressure, or total cholesterol.
Source: Stroke - December 22, 2016 Category: Neurology Authors: Inger A. Deijle, Sander M. Van Schaik, Erwin E.H. Van Wegen, Henry C. Weinstein, Gert Kwakkel, Renske M. Van den Berg-Vos Tags: Lifestyle, Secondary Prevention, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Statins and the Risk of Intracerebral Hemorrhage in Patients With Previous Ischemic Stroke or Transient Ischemic Attack Clinical Sciences
Conclusions—Statin use was not associated with an increased risk of ICH among patients with a previous history of IS/TIA.
Source: Stroke - November 27, 2017 Category: Neurology Authors: David Gaist, Larry B. Goldstein, Lucia Cea Soriano, Luis Alberto Garcia Rodriguez Tags: Secondary Prevention, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Risk Profile of Symptomatic Lacunar Stroke Versus Nonlobar Intracerebral Hemorrhage Brief Reports
Conclusions— The risk factor profile of dICH differs from that associated with LS. This might be used for disease risk stratification at individual level.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Morotti, A., Paciaroni, M., Zini, A., Silvestrelli, G., Del Zotto, E., Caso, V., DellAcqua, M. L., Simone, A. M., Lanari, A., Costa, P., Poli, L., De Giuli, V., Gamba, M., Ciccone, A., Ritelli, M., Di Castelnuovo, A., Iacoviello, L., Colombi, M., Agnelli, Tags: Intracranial Hemorrhage, Ischemic Stroke Brief Reports Source Type: research

Association between atherogenic dyslipidemia and recurrent stroke risk in patients with different subtypes of ischemic stroke
ConclusionsAtherogenic dyslipidemia is associated with higher risk of stroke recurrence in ischemic stroke patients. Such association might be more pronounced in large‐artery atherosclerosis subtype and needs further investigation to establish such relationship.
Source: International Journal of Stroke - April 28, 2015 Category: Neurology Authors: Lu Zhao, Ruihao Wang, Bo Song, Song Tan, Yuan Gao, Hui Fang, Jie Lu, Yuming Xu Tags: Research Source Type: research

Impact of stroke misdiagnosis on short-term and discharge use of vascular medications in young adults (P7.125)
CONCLUSIONS: ED stroke misdiagnosis was associated with reduced use of early AT. At discharge, there was no variation in antithrombotic or statin use based on stroke misdiagnosis. Fewer than half of cryptogenic stroke patients received statins. Greater statin use in this population could reduce the rate of major vascular events Study Supported by: None Disclosure: Dr. Chaturvedi has received personal compensation for activities with Genentech, Inc., Abbott Vascular, Boehringer-Ingelheim, WL Gore, and Merck. Dr. Chaturvedi has received personal compensation in an editorial capacity for NEJM Jour...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Chaturvedi, S., Rajamani, K. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke in Young Source Type: research

Special MRI scan could identify stroke risk in people with atrial fibrillation
Atrial fibrillation is a heart rhythm disorder that affects millions of people. It can make you feel lousy. Even worse, it can cause potentially disabling or deadly strokes. A special MRI scan may — I stress the “may” — help identify people with atrial fibrillation who are at high risk of having a stroke. This could help many people with this condition to avoid taking warfarin or other clot-preventing medications for life. A normal heartbeat starts in a cluster of cells called the pacemaker. It sits in the heart’s upper right chamber (the right atrium). These cells generate a pulse of electricity that...
Source: New Harvard Health Information - April 28, 2015 Category: Consumer Health News Authors: Howard LeWine, M.D. Tags: Heart Health atrial fibrillation MRI prevention special MRI scan Stroke Stroke Risk Source Type: news

Atorvastatin Treatment Is Associated with Increased BDNF Level and Improved Functional Recovery after Atherothrombotic Stroke (S31.007)
Conclusions: Our results demonstrated that atorvastatin treatment was associated with increased BDNF level and improved functional recovery after atherothrombotic stroke. This study indicates that atorvastatin-related elevation in BDNF may promote functional recovery in stroke patients.Disclosure: Dr. Zhang has nothing to disclose. Dr. Mu has nothing to disclose. Dr. Gao has nothing to disclose. Dr. Huang has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zhang, J., Mu, X., Gao, Z., Huang, Y. Tags: Stroke Risk, Outcomes, and Complications Source Type: research

Primary prevention of stroke by a healthy lifestyle in a high-risk group
Conclusions: A healthy lifestyle is associated with a substantially reduced risk of stroke in men at higher risk of stroke.
Source: Neurology - June 1, 2015 Category: Neurology Authors: Larsson, S. C., Akesson, A., Wolk, A. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Cohort studies ARTICLE Source Type: research

Rates and predictors of risk of stroke and its subtypes in diabetes: a prospective observational study
Conclusions Older people with a history of stroke were at highest risk of stroke, but the prognosis and prognostic factors of subtypes were heterogeneous. The results will help clinicians quantify the absolute risk of stroke and its subtypes for typical diabetes patients.
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 15, 2013 Category: Neurosurgery Authors: Hankey, G. J., Anderson, N. E., Ting, R.-D., Veillard, A.-S., Romo, M., Wosik, M., Sullivan, D. R., O'Connell, R. L., Hunt, D., Keech, A. C. Tags: Stroke, Hypertension, Ophthalmology, Ischaemic heart disease Cerebrovascular disease Source Type: research

Long term risk of stroke versus acute coronary events after tia and stroke: a population-based study
Conclusion The long–term risk of major vascular events after TIA and stroke remains substantial, but about 70% of fatal and non–fatal events are now accounted for by recurrent stroke rather than acute coronary events.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Paul, N. L., Mehta, Z., Silver, L., Geraghty, O. C., Rothwell, P. M. Tags: Stroke, Ischaemic heart disease Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

A comparative analysis of risk factors and stroke risk for Asian and non‐Asian men: The Asia Pacific Cohort Studies Collaboration
ConclusionsMen from the Asia‐Pacific region share common risk factors for stroke. Strategies aimed at lowering population levels of systolic blood pressure, total cholesterol, body mass index, smoking, and diabetes are likely to be beneficial in reducing stroke risk, particularly for ischemic stroke, across the region.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Karice K. Hyun, Rachel R. Huxley, Hisatomi Arima, Jean Woo, Tai Hing Lam, Hirotsugu Ueshima, Xianghua Fang, Sanne A. E. Peters, Sun Ha Jee, Graham G. Giles, Federica Barzi, Mark Woodward Tags: Research Source Type: research

Incidence, Trends, and Predictors of Ischemic Stroke 30 Days After an Acute Myocardial Infarction Clinical Sciences
Conclusions— The incidence of ischemic stroke within 30 days of an AMI has decreased during the period 1998 to 2008. This decrease is associated with increased use of acetylsalicylic acid, P2Y12 inhibitors, statins, and percutaneous coronary intervention.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Kajermo, U., Ulvenstam, A., Modica, A., Jernberg, T., Mooe, T. Tags: Risk Factors, Acute myocardial infarction, Acute Cerebral Infarction, Epidemiology Clinical Sciences Source Type: research

Secular Trends in Ischemic Stroke Subtypes and Stroke Risk Factors Clinical Sciences
Conclusions— With more intensive medical management in the community, a significant decrease in atherosclerotic risk factors was observed, with a significant decline in stroke/transient ischemic attack caused by large artery atherosclerosis and small vessel disease. As a result, cardioembolic stroke/transient ischemic attack has increased significantly. Our findings suggest that more intensive investigation for cardiac sources of embolism and greater use of anticoagulation may be warranted.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Bogiatzi, C., Hackam, D. G., McLeod, A. I., Spence, J. D. Tags: Other diagnostic testing Clinical Sciences Source Type: research

Infection, vaccination, and childhood arterial ischemic stroke
A stroke occurs when a blood vessel to the brain is either blocked or ruptured. When blood to part of the brain is blocked, it causes what is called an ischemic stroke. Stroke is much more common in adults and the elderly. This is because fats and cholesterol can build up and block blood vessels as we age. Stroke is much less common in children. Stroke occurs in 11 per 100,000 children under the age of 18 every year.1 Still, it is one of the top 10 causes of death for children.2 We don't routinely expect children to have the major risk factors for atherosclerosis, such as high blood pressure, diabetes, high cholesterol, an...
Source: Neurology - October 26, 2015 Category: Neurology Authors: Woo, D. Tags: Childhood stroke, All Infections, All Cerebrovascular disease/Stroke, All Pediatric, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke PATIENT PAGES Source Type: research

Statin pretreatment is associated with better outcomes in large artery atherosclerotic stroke
Conclusion: Statin pretreatment in patients with acute LAA appears to be associated with better early outcomes regarding neurologic improvement, disability, survival, and stroke recurrence.
Source: Neurology - March 21, 2016 Category: Neurology Authors: Tsivgoulis, G., Katsanos, A. H., Sharma, V. K., Krogias, C., Mikulik, R., Vadikolias, K., Mijajlovic, M., Safouris, A., Zompola, C., Faissner, S., Weiss, V., Giannopoulos, S., Vasdekis, S., Boviatsis, E., Alexandrov, A. W., Voumvourakis, K., Alexandrov, A Tags: All Cerebrovascular disease/Stroke, Infarction ARTICLE Source Type: research