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Attenuating lipid metabolism in atherosclerosis: The potential role of Anti-oxidative effects on low-density lipoprotein of herbal medicines
Front Pharmacol. 2023 Mar 31;14:1161657. doi: 10.3389/fphar.2023.1161657. eCollection 2023.ABSTRACTAtherosclerosis (AS) is a multifactorial chronic disease with great harm to the health of human being, which is a basic pathogenesis of many cardiovascular diseases and ultimately threatens human life. Abnormal blood lipid level is one of the most common diagnostic indicators of AS in clinic, and lipid metabolism disorder is often observed in patients with AS. Cholesterol is an important lipid in the human body, which is of great significance for maintaining normal life activities. Generally, cholesterol is transported to per...
Source: Atherosclerosis - April 17, 2023 Category: Cardiology Authors: Huxinyue Duan Pan Song Ruolan Li Hong Su Lisha He Source Type: research

The efficacy and safety of Chinese herbal medicine as an add-on therapy for type 2 diabetes mellitus patients with carotid atherosclerosis: An updated meta-analysis of 27 randomized controlled trials
Conclusion: Based on this meta-analysis, we found that in the treatment of T2DM patients with CAS, combined with CHM may have more advantages than WM alone, which can further reduce CIMT and carotid plaque Crouse score, regulate glucose and lipid metabolism, improve insulin resistance and enhance islet β-cell function. Meanwhile, CHM is relatively safe. However, limited by the quality and heterogeneity of included studies, the efficacy and safety of CHM remain uncertain. More high-quality studies are still needed to provide more reliable evidence for the clinical application of CHM. Systematic Review Registration: https:/...
Source: Atherosclerosis - April 10, 2023 Category: Cardiology Authors: Zehua Zhang Yulin Leng Zhengtao Chen Xiaoxu Fu Qingzhi Liang Xi Peng Hongyan Xie Hong Gao Chunguang Xie Source Type: research

Guanmaitong Granule Attenuates Atherosclerosis by Inhibiting Inflammatory Immune Response in ApoE < sup > -/- < /sup > Mice Fed High-Fat Diet
CONCLUSION: Radix notoginseng, Radix salviae liguliobae, and Radix astragali are the main ingredients of GMTG for treating AS. Further, GMTG could regulate the level of serum lipids and inhibit inflammatory immune response, which resulted in anti-AS effects such as plaque stabilization, reduction of plaque burden, and plaque remodeling. GMTG is a promising multi-target treatment for AS.PMID:36148321 | PMC:PMC9489104 | DOI:10.2147/DDDT.S372143
Source: Atherosclerosis - September 23, 2022 Category: Cardiology Authors: Mengqi Yang Huachen Jiao Yan Li Lei Zhang Juan Zhang Xia Zhong Yitao Xue Source Type: research

Efficacy and safety of Chinese herbal for carotid atherosclerosis: A protocol for systematic review and network meta-analysis
CONCLUSION: The study will offer more evidence for the treatment of CAS with Chinese herbal and expand the selection range of clinicians.PROTOCOL REGISTRATION NUMBER: INPLASY2021100112.PMID:34964762 | DOI:10.1097/MD.0000000000027909
Source: Atherosclerosis - December 29, 2021 Category: Cardiology Authors: Haitao Li Hongwei Zhi Xiying Xu Yahan Wang Shuai Zhang Sishuo Zhang Source Type: research

Herbal Approach for Management of Atherosclerosis: a Review
AbstractPurpose of ReviewSummarize of the reports on antioxidants especially from herbal sources which battle oxidative stress might be proficient to forestall and repair the free radical –prompted vascular damages in overseeing of atherosclerosis.Recent FindingsAtherosclerosis is the one of the fundamental reason for hypertension, stroke, myocardial localized necrosis, and numerous other cardiovascular illnesses. Atherosclerosis associated path physiological factors like hypercholesterolemia, hypertension, diabetes mellitus, and smoking actuates oxidative stress which are characterized by excessive oxidation and imprope...
Source: Current Atherosclerosis Reports - February 28, 2019 Category: Cardiology Source Type: research

Treatment of atherosclerosis by traditional Chinese medicine: Questions and quandaries
Atherosclerosis and its complications, such as myocardial infarction and stroke, are the major causes of morbidity and mortality, and development of effective therapeutics for both prevention and treatment of this disease is critically important. Currently, there are many drugs available for atherosclerotic disease, but the lipid-lowering drugs statins are still the first-choice for treatment of hypercholesterolemia, a major risk factor for atherosclerosis. On the other hand, traditional Chinese medicines, mainly Chinese herbal medicines (CHM), have been widely used in China and in other Asian countries for the treatment o...
Source: Atherosclerosis - August 30, 2018 Category: Cardiology Authors: Chuan Wang, Manabu Niimi, Teruo Watanabe, Yanli Wang, Jingyan Liang, Jianglin Fan Tags: Review article Source Type: research

Abstract 228: Assessing Knowledge, Perceptions, and Cultural Attitudes Towards Stroke in Elderly Korean-Americans: The Strengthening Our Korean Elders Through Community-Partnered Education (STROKE-COPE) Project Poster Session II
Conclusions: Elderly Korean-Americans have substantial risk for stroke, but possess both language and belief barriers that may interfere with stroke prevention and response. A stroke education curriculum tailored for elderly Korean-Americans must address these culturally specific beliefs to be effective.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: Song, S., Son, J. B., Park, H., Park, H., Community Advisory Panel, T. S.-C., Ryan, G., Vickrey, B. Tags: Poster Session II Source Type: research