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Preoperative evaluation and comprehensive risk assessment for children with Down syndrome
Summary Down syndrome is a common chromosome disorder affecting all body systems. This creates unique physiologic concerns that can affect safety during anesthesia and surgery. Little consensus exists, however, on the best way to evaluate children with Down syndrome in preparation for surgery. We review a number of salient topics affecting these children in the perioperative period, including cervical spine instability, cardiovascular abnormalities, pulmonary hypertension, upper airway obstruction, hematologic disturbances, prematurity, low birth weight, and the use of supplements and alternative therapies. Recommendations...
Source: Pediatric Anesthesia - January 12, 2016 Category: Anesthesiology Authors: Amy Feldman Lewanda, Andrew Matisoff, Mary Revenis, Ashraf Harahsheh, Craig Futterman, Gustavo Nino, Jay Greenberg, John S. Myseros, Kenneth N. Rosenbaum, Marshall Summar Tags: Special Interest Article (Review) Source Type: research

Preoperative evaluation and comprehensive risk assessment for children with Down syndrome.
Abstract Down syndrome is a common chromosome disorder affecting all body systems. This creates unique physiologic concerns that can affect safety during anesthesia and surgery. Little consensus exists, however, on the best way to evaluate children with Down syndrome in preparation for surgery. We review a number of salient topics affecting these children in the perioperative period, including cervical spine instability, cardiovascular abnormalities, pulmonary hypertension, upper airway obstruction, hematologic disturbances, prematurity, low birth weight, and the use of supplements and alternative therapies. Recom...
Source: Paediatric Anaesthesia - January 9, 2016 Category: Anesthesiology Authors: Lewanda AF, Matisoff A, Revenis M, Harahsheh A, Futterman C, Nino G, Greenberg J, Myseros JS, Rosenbaum KN, Summar M Tags: Paediatr Anaesth Source Type: research