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Morbidity and Mortality Associated With Balloon Aortic Valvuloplasty: A National Perspective Structural Heart Disease
Conclusions— In a contemporary national registry, BAV is associated with significant morbidity and mortality that are similar to TAVR. With the substantial increase in BAV utilization and the continuous improvement in TAVR outcomes, these data have important implications to aid clinicians in the selection of appropriate BAV candidates.
Source: Circulation: Cardiovascular Interventions - May 11, 2017 Category: Cardiology Authors: Alkhouli, M., Zack, C. J., Sarraf, M., Bashir, R., Nishimura, R. A., Eleid, M. F., Nkomo, V. T., Sandhu, G. S., Gulati, R., Greason, K. L., Holmes, D. R., Rihal, C. S. Tags: Aortic Valve Replacement/Transcatheter Aortic Valve Implantation, Catheter-Based Coronary and Valvular Interventions Structural Heart Disease Source Type: research

Outcome With the Repositionable and Retrievable Boston Scientific Lotus Valve Compared With the Balloon-Expandable Edwards Sapien 3 Valve in Patients Undergoing Transfemoral Aortic Valve Replacement Structural Heart Disease
Conclusions— Transfemoral aortic valve replacement with the ES3 and the Lotus were associated with similar 30-day, 12-month, and 24-month clinical outcomes. Need for permanent pacemaker implantation was significantly higher with the repositionable Lotus device. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT02162069.
Source: Circulation: Cardiovascular Interventions - May 31, 2017 Category: Cardiology Authors: Seeger, J., Gonska, B., Rottbauer, W., Wohrle, J. Tags: Aortic Valve Replacement/Transcatheter Aortic Valve Implantation Structural Heart Disease Source Type: research

Metoprolol Reduces Hemodynamic and Metabolic Overload in Asymptomatic Aortic Valve Stenosis Patients: A Randomized Trial Ventricular Structure and Function
Conclusions— In patients with asymptomatic AS, metoprolol increases systolic ejection time and reduces aortic valve gradients, global afterload, and myocardial oxygen requirements. Thus, metoprolol displays favorable hemodynamic and metabolic effects and could improve outcome in patients with asymptomatic AS. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT02076711.
Source: Circulation: Cardiovascular Imaging - September 27, 2017 Category: Radiology Authors: Hansson, N. H., Sorensen, J., Harms, H. J., Kim, W. Y., Nielsen, R., Tolbod, L. P., Frokiaer, J., Bouchelouche, K., Dodt, K. K., Sihm, I., Poulsen, S. H., Wiggers, H. Tags: Clinical Studies, Metabolism, Valvular Heart Disease, Imaging, Nuclear Cardiology and PET Ventricular Structure and Function Source Type: research

Postoperative Reverse Remodeling and Symptomatic Improvement in Normal-Flow Low-Gradient Aortic Stenosis After Aortic Valve Replacement Valvular Heart Disease
Conclusions— Patients with NFLG had less severe AS and LV remodeling than patients with normal-flow high-gradient. Furthermore, NFLG patients experienced less reverse remodeling but the same symptomatic benefit. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT02316587.
Source: Circulation: Cardiovascular Imaging - December 8, 2017 Category: Radiology Authors: Carter-Storch, R., Moller, J. E., Christensen, N. L., Irmukhadenov, A., Rasmussen, L. M., Pecini, R., Ovrehus, K. A., Sondergard, E. V., Marcussen, N., Dahl, J. S. Tags: Valvular Heart Disease, Aortic Valve Replacement/Transcatheter Aortic Valve Implantation Source Type: research

Treatment of Aortic Stenosis With a Self-Expanding, Resheathable Transcatheter Valve: One-Year Results of the International Multicenter Portico Transcatheter Aortic Valve Implantation System Study Structural Heart Disease
Conclusions— The Portico TAVI system is safe and effective at 1 year, yielding low mortality and stroke rates in high-risk patients with severe AS. Clinical Trial Registration— URL: https://www.clinicaltrials.gov. Unique identifier: NCT01493284.
Source: Circulation: Cardiovascular Interventions - February 14, 2018 Category: Cardiology Authors: Linke, A., Holzhey, D., Mollmann, H., Manoharan, G., Schafer, U., Frerker, C., Worthley, S. G., van Boven, A. J., Redwood, S., Kovac, J., Butter, C., Sondergaard, L., Lauten, A., Schymik, G., Walther, T. Tags: Aortic Valve Replacement/Transcatheter Aortic Valve Implantation Structural Heart Disease Source Type: research

Hemodynamic Characteristics in Significant Symptomatic and Asymptomatic Primary Mitral Valve Regurgitation at Rest and During Exercise Valvular Heart Disease
Conclusions— Symptoms in patients with severe mitral valve regurgitation relate to congestion (pulmonary capillary wedge pressure and PAP), but not to peak oxygen consumption, which is determined by forward left ventricular stroke volume. Exercise testing reveals a higher mitral valve regurgitation burden in apparently asymptomatic patients. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT02961647.
Source: Circulation: Cardiovascular Imaging - February 15, 2018 Category: Radiology Authors: Bakkestrom, R., Banke, A., Christensen, N. L., Pecini, R., Irmukhamedov, A., Andersen, M., Borlaug, B. A., Moller, J. E. Tags: Valvular Heart Disease, Echocardiography, Exercise Testing, Magnetic Resonance Imaging (MRI) Source Type: research

Registry of antithrombotic therapy in atrial fibrillation patients with bioprosthetic valves: A retrospective observational study.
CONCLUSIONS: In a current real-world setting in Japan, warfarin was the most commonly used treatment in AF patients with bioprosthetic valves, but there was an increasing trend of DOAC-treated patients. Further investigations are needed to confirm the efficacy and safety of DOAC in patients with bioprosthetic valves. PMID: 32156512 [PubMed - as supplied by publisher]
Source: Journal of Cardiology - March 6, 2020 Category: Cardiology Authors: Izumi C, Miyake M, Amano M, Kitai T, Obayashi Y, Takegami M, Kimura T, Sugio K, Matsumoto T, Nishimura K, Furukawa Y Tags: J Cardiol Source Type: research

Aortic Valve Replacement in Young and Middle-Aged Adults: Current and Potential Roles of TAVR.
CONCLUSIONS: TAVR is increasingly used for adults <55 years. Given the uniformly excellent results with SAVR, including both mortality and morbidity - particularly regarding stroke, our data favor SAVR in this population, but a prospective trial is needed. Ongoing efforts to harmonize variables and outcomes definitions between the ACSD and CHSD are valuable. PMID: 32768428 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - August 4, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Nelson J, Maul T, Wearden P, Najm HK, Baloglu O, Johnston D, Karamlou T Tags: Ann Thorac Surg Source Type: research

Comparison of the long-term outcomes and risk factors of aortic stenosis treatment - in patients undergoing transcatheter aortic valve implantation and surgical aortic valve replacement
CONCLUSIONS: There were no significant differences regarding prognosis after TAVI and SAVR at the 24-month follow-up in propensity score matching model. Independent predictive factors of late mortality after both procedures were EuroScore II and the respiratory failure. Independent predictive factors of late mortality specific for TAVI were NOAF, increased RDW and for SAVR: TIA, stroke, COPD and RBC transfusion.PMID:35521716 | DOI:10.33963/KP.a2022.0122
Source: Polish Heart Journal - May 6, 2022 Category: Cardiology Authors: Karolina Marzec Maria Jaworska-Wilczy ńska Ilona Kowalik Ma łgorzata Nieznańska Adam Witkowski Maciej D ąbrowski Krzysztof Ku śmierski Tomasz Hryniewiecki Source Type: research

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