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Psychosocial stress and major cardiovascular events in patients with stable coronary heart disease
ConclusionsPsychosocial stress, such as depressive symptoms, loss of interest, living alone, and financial stress, was associated with increased CV mortality in patients with stable CHD despite optimal medical secondary prevention treatment. Secondary prevention of CHD should therefore focus also on psychosocial issues both in clinical management and in future clinical trials.This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - September 28, 2017 Category: Internal Medicine Authors: Emil Hagstr öm, Fredrika Norlund, Amanda Stebbins, Paul W Armstrong, Karen Chiswell, Christopher B Granger, José López‐Sendón, Daniel Pella, Joseph Soffer, Rody Sy, Lars Wallentin, Harvey D White, Ralph A H Stewart, Claes Held, Tags: Original Source Type: research

Integrative studies implicate matrix metalloproteinase ‐12 as a culprit gene for large‐artery atherosclerotic stroke
ConclusionsOur study supports the notion that MMP12 is implicated in large‐artery atherosclerotic stroke, functionally by enhancing elastin degradation and macrophage invasion in plaques.
Source: Journal of Internal Medicine - August 28, 2017 Category: Internal Medicine Authors: H. Mahdessian, L. Perisic Matic, M. Lengquist, K. Gertow, B. Sennblad, D. Baldassarre, F. Veglia, S. E. Humphries, R. Rauramaa, U. Faire, A. J. Smit, P. Giral, S. Kurl, E. Mannarino, E. Tremoli, A. Hamsten, P. Eriksson, U. Hedin, A. M älarstig, Tags: Original Article Source Type: research

Integrative Studies Implicate Matrix Metalloproteinase 12 as a Culprit Gene for Large ‐Artery Atherosclerotic Stroke
ConclusionsOur study supports the notion that MMP12 is implicated in large‐artery atherosclerotic stroke, functionally by enhancing elastin degradation and macrophage invasion in plaques.This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - July 22, 2017 Category: Internal Medicine Authors: Hovsep Mahdessian, Ljubica Perisic Matic, Mariette Lengquist, Karl Gertow, Bengt Sennblad, Damiano Baldassarre, Fabrizio Veglia, Steve E. Humphries, Rainer Rauramaa, Ulf Faire, Andries J. Smit, Philippe Giral, Sudhir Kurl, Elmo Mannarino, Elena Tremoli, A Tags: Original Article Source Type: research

Potential health hazards of eating red meat
Abstract Red meat (beef, veal, pork, lamb and mutton) consumption contributes several important nutrients to the diet, for example essential amino acids, vitamins (including B12) and minerals (including iron and zinc). Processed red meat (ham, sausages, bacon, frankfurters, salami, etc.) undergoes treatment (curing, smoking, salting or the use of chemical preservatives and additives) to improve its shelf life and/or taste. During recent decades, consumption of red meat has been increasing globally, especially in developing countries. At the same time, there has been growing evidence that high consumption of red meat, espec...
Source: Journal of Internal Medicine - August 31, 2016 Category: Internal Medicine Authors: A. Wolk Tags: Review Source Type: research

Treatment of acute stroke: an update
Abstract Stroke is the second leading cause of global mortality after coronary heart disease, and a major cause of neurological disability. About 17 million strokes occur worldwide each year. Patients with stroke often require long‐term rehabilitation following the acute phase, with ongoing support from the community and nursing home care. Thus, stroke is a devastating disease and a major economic burden on society. In this overview, we discuss current strategies for specific treatment of stroke in the acute phase, focusing on intravenous thrombolysis and mechanical thrombectomy. We will consider two important issues re...
Source: Journal of Internal Medicine - July 1, 2015 Category: Internal Medicine Authors: R. Mikulik, N. Wahlgren Tags: Review Source Type: research

No association between adherence to the healthy Nordic food index and cardiovascular disease amongst Swedish women: a cohort study
ConclusionThe present results do not support an association between a healthy Nordic food index and risk of cardiovascular disease in Swedish women. There was also no effect modification by alcohol intake, BMI or age. Our finding of an interaction with smoking status requires reproduction.
Source: Journal of Internal Medicine - May 19, 2015 Category: Internal Medicine Authors: N. Roswall, S. Sandin, R. Scragg, M. Löf, G. Skeie, A. Olsen, H.‐O. Adami, E. Weiderpass Tags: Original Article Source Type: research

Ceruloplasmin dysfunction: a key factor in the pathophysiology of atrial fibrillation?
This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - November 5, 2013 Category: Internal Medicine Authors: Jamie Y Jeremy, Nilima Shukla Tags: Editorial Comment Source Type: research