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Specialty: Universities & Medical Training
Condition: Heart Failure

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Total 205 results found since Jan 2013.

SGLT2 Inhibitors: The Next Blockbuster Multifaceted Drug?
Medicina (Kaunas). 2023 Feb 16;59(2):388. doi: 10.3390/medicina59020388.ABSTRACTSodium glucose cotransporter 2 inhibitor (SGLT2i) is a class of drugs that were originally intended for decreasing blood glucose in diabetes. However, recent trials have shown that there are other beneficial effects. Major clinical trials involving SGLT2i medications from 2015 to 2022 were reviewed using PUBMED search. Recent major SGLT2i landmark trials have demonstrated benefits for cardiovascular disease (reduce major adverse cardiovascular events (heart attack, stroke, cardiovascular death), hospitalization for heart failure, all-cause deat...
Source: Medicina (Kaunas) - February 25, 2023 Category: Universities & Medical Training Authors: Jonathan C H Chan Michael C Y Chan Source Type: research

Heat and the Heart
Yale J Biol Med. 2023 Jun 30;96(2):197-203. doi: 10.59249/HGAL4894. eCollection 2023 Jun.ABSTRACTGlobally, more people die from cardiovascular disease than any other cause. Extreme heat can have serious implications for heart health, especially in people with pre-existing cardiovascular conditions. In this review, we examined the relationship between heat and the leading causes of cardiovascular diseases as well as the proposed physiological mechanisms for the deleterious effect of heat on the heart. The body's response to high temperatures, including dehydration, increased metabolic demand, hypercoagulability, electrolyte...
Source: The Yale Journal of Biology and Medicine - July 3, 2023 Category: Universities & Medical Training Authors: Yash Desai Haitham Khraishah Barrak Alahmad Source Type: research