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Cancers, Vol. 13, Pages 6203: Acute and Long-Term Outcomes of ST-Elevation Myocardial Infarction in Cancer Patients, a & lsquo;Real World & rsquo; Analysis with 175,000 Patients
Conclusion: In this large “real world” data, prognosis after STEMI in cancer patients was markedly reduced but differed widely between cancer types. Of note, no withholding of interventional treatments in cancer patients could be observed.
Source: Cancers - December 9, 2021 Category: Cancer & Oncology Authors: Stefan A. Lange Jannik Feld Leonie K ühnemund Jeanette K öppe Lena Makowski Christiane M. Engelbertz Joachim Ger ß Patrik Dr öge Thomas Ruhnke Christian G ünster Eva Freisinger Holger Reinecke Tags: Article Source Type: research

Cancers, Vol. 13, Pages 2254: Adjuvant Hormonotherapy and Cardiovascular Risk in Post-Menopausal Women with Breast Cancer: A Large Population-Based Cohort Study
Conclusions: Adjuvant therapy with AI in breast cancer women aged more than 50 years is associated with increased risk of heart failure and combined CV events.
Source: Cancers - May 8, 2021 Category: Cancer & Oncology Authors: Matteo Franchi Roberta Tritto Luigi Tarantini Alessandro Navazio Giovanni Corrao Tags: Article Source Type: research

Cancers, Vol. 13, Pages 1732: Substance P Antagonism Prevents Chemotherapy-Induced Cardiotoxicity
Conclusions: Our studies indicate that the SP/NK1-R system is a key mediator that induces, DOX-induced, cardiac dysfunction, cardiac apoptosis, cardiac oxidative stress and cardiomyocyte hypertrophy. These studies implicate that NK-1R antagonists may serve as a novel therapeutic tool for prevention of chemotherapy induced cardiotoxicity in cancer.
Source: Cancers - April 6, 2021 Category: Cancer & Oncology Authors: Ashiq Legi Emma Rodriguez Thomas K. Eckols Cyrus Mistry Prema Robinson Tags: Article Source Type: research

Cancers, Vol. 12, Pages 189: Influence of Baseline Cardiovascular Comorbidities on Mortality after Androgen Deprivation Therapy for Metastatic Prostate Cancer
ih Shao Few studies have assessed the benefits of androgen deprivation therapy (ADT) in men with metastatic prostate cancer (PC; mPC) at an old age or with major cardiovascular conditions. A retrospective cohort consisted of 3835 men with newly diagnosed mPC from the Taiwan Cancer Registry of 2008–2014. Among them, 2692 patients received only ADT in the first year after the cancer diagnosis, and 1143 patients were on watchful waiting. The inverse probability of treatment-weighted Cox model was used to estimate the effects of ADT on all-cause mortality and PC-specific mortality according to age, and the...
Source: Cancers - January 11, 2020 Category: Cancer & Oncology Authors: Wu Fang Hwang Shih Shao Tags: Article Source Type: research