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Source: ESC Heart Failure
Condition: Heart Failure
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Total 167 results found since Jan 2013.
Direct oral anticoagulants compared to vitamin K antagonist for the management of left ventricular thrombus
ConclusionsOur data suggest that DOACs are likely to be at least as effective and safe as VKA for stroke prevention in patients with LV thrombus and, despite their lack of a licence for this indication, are therefore likely to represent a reasonable and more convenient option for this setting. The optimal timing and type of anticoagulation for LV thrombus, as well as the role of screening for high ‐risk patients, should be tested in prospective, randomized trials.
Source: ESC Heart Failure - June 24, 2020 Category: Cardiology Authors: Hansa Iqbal,
Sam Straw,
Thomas P. Craven,
Katherine Stirling,
Stephen B. Wheatcroft,
Klaus K. Witte Tags: Original Research Article Source Type: research
Novel oral anticoagulant vs. warfarin in elderly atrial fibrillation patients with normal, mid ‐range, and reduced left ventricular ejection fraction
ConclusionsIn elderly AF patients ≥65 years, using NOAC was associated with lower IS/SE compared with warfarin in normal and mid‐range LVEF but not in reduced LVEF. Using NOACs was associated with lower death compared with warfarin in normal LVEF.
Source: ESC Heart Failure - July 15, 2020 Category: Cardiology Authors: Victor Chien ‐Chia Wu,
Chun‐Li Wang,
Cheng‐Hung Lee,
Yu‐Ling Chen,
Hui‐Tzu Tu,
Michael Wu,
Chang‐Fu Kuo,
Shao‐Wei Chen,
Yu‐Tung Huang,
Ming‐Shien Wen,
Shang‐Hung Chang Tags: Original Research Article Source Type: research
Plasma proteoglycan prolargin in diagnosis and differentiation of pulmonary arterial hypertension
ConclusionsPlasma prolargin levels differentiate PAH patients from controls and the other investigated dyspnoea groups including HF. Its potential in PAH differentiation may be enhanced by inclusion in a multi ‐marker panel. Larger studies are needed to evaluate its discriminative ability of PAH in relation to other dyspnoea aetiologies and its potential role in PAH risk stratification and pathobiology.
Source: ESC Heart Failure - January 5, 2021 Category: Cardiology Authors: Mattias Arvidsson,
Abdulla Ahmed,
Habib Bouzina,
G öran Rådegran Tags: Original Research Article Source Type: research
Characteristics, treatment, and outcomes of newly diagnosed atrial fibrillation patients with heart failure: GARFIELD ‐AF
ConclusionsPatients with AF and HF have a high risk of all ‐cause and cardiovascular mortality and stroke/systemic embolism and may develop worsening HF.
Source: ESC Heart Failure - January 12, 2021 Category: Cardiology Authors: Giuseppe Ambrosio,
Jean ‐Pierre Bassand,
Ramon Corbalan,
Gloria Kayani,
Erberto Carluccio,
Lorenzo G. Mantovani,
Saverio Virdone,
Ajay K. Kakkar,
A. John Camm,
for the GARFIELD‐AF Investigators Tags: Original Research Article Source Type: research
Plasma proteoglycan prolargin in diagnosis and differentiation of pulmonary arterial hypertension
ConclusionsPlasma prolargin levels differentiate PAH patients from controls and the other investigated dyspnoea groups including HF. Its potential in PAH differentiation may be enhanced by inclusion in a multi ‐marker panel. Larger studies are needed to evaluate its discriminative ability of PAH in relation to other dyspnoea aetiologies and its potential role in PAH risk stratification and pathobiology.
Source: ESC Heart Failure - March 29, 2021 Category: Cardiology Authors: Mattias Arvidsson,
Abdulla Ahmed,
Habib Bouzina,
G öran Rådegran Tags: Original Research Article Source Type: research
Effects of different exercise modalities on cardiac dysfunction in heart failure with preserved ejection fraction
ConclusionsIn this metabolic rat model of HFpEF at an advanced stage, Ca2+ release was impaired under baseline conditions. HIIT and MICT differentially affected Ca2+ homeostasis with positive effects of MICT on stroke volume, end ‐diastolic volume, and cellular arrhythmogenicity.
Source: ESC Heart Failure - March 26, 2021 Category: Cardiology Authors: David Bode,
Natale P.L. Rolim,
Tim Guthof,
Niklas Hegemann,
Paulina Wakula,
Uwe Primessnig,
Anne Marie Ormbostad Berre,
Volker Adams,
Ulrik Wisl øff,
Burkert M. Pieske,
Frank R. Heinzel,
Felix Hohendanner,
OptimEx Study Group Tags: Original Research Article Source Type: research
Long ‐term clinical and haemodynamic results after transcatheter annuloplasty for secondary mitral regurgitation
ConclusionsAmong high ‐risk patients undergoing transcatheter mitral valve annuloplasty for symptomatic secondary MR, mortality was ~50% at 4 years. In the surviving patients, reduced MR severity was associated with reduced NYHA functional class, reverse LV remodelling, and improved LV function.
Source: ESC Heart Failure - May 3, 2021 Category: Cardiology Authors: Daniel Lavall,
Julius Bruns,
Tina Stegmann,
Andreas Hagendorff,
Stephan St öbe,
Ulrich Laufs Tags: Original Research Article Source Type: research
Left atrial conduit flow rate at baseline and during exercise: an index of impaired relaxation in HFpEF patients
ConclusionsIn HFpEF, conduit flow rate decreases when diastolic dysfunction develops during exercise, in parallel with changes in LV inotropic state and torsion, contributing to impaired stroke volume reserve. Conduit flow is measurable using 3D-echocardiographic full-volume atrio-ventricular datasets, and as a marker of LV relaxation can contribute to the diagnosis of HFpEF.
Source: ESC Heart Failure - August 10, 2021 Category: Cardiology Authors: Paolo N. Marino,
Jacopo Zanaboni,
Anna Degiovanni,
Chiara Sartori,
Giuseppe Patti,
Alan G. Fraser Tags: Short Communication Source Type: research
Atrial fibrillation before heart transplantation is a risk factor for post ‐transplant atrial fibrillation and mortality
ConclusionsAtrial fibrillation before HTX is a risk factor for post-transplant AF, permanent pacemaker implantation, and mortality after HTX.
Source: ESC Heart Failure - August 28, 2021 Category: Cardiology Authors: Fabrice F. Darche,
Matthias Helmschrott,
Ann ‐Kathrin Rahm,
Dierk Thomas,
Patrick A. Schweizer,
Tom Bruckner,
Philipp Ehlermann,
Michael M. Kreusser,
Gregor Warnecke,
Norbert Frey,
Rasmus Rivinius Tags: Original Research Article Source Type: research
Anticoagulation in cardiomyopathy: unravelling the hidden threat and challenging the threat individually
AbstractCardiomyopathy comprises a heterogeneous group of myocardial abnormalities, structural or functional in nature, in the absence of coronary artery disease and other abnormal loading conditions. These myocardial pathologies can result in premature death or disability from progressive heart failure, arrhythmia, stroke, or other embolic events. The European Cardiomyopathy Registry reports a high stroke risk in cardiomyopathy patients ranging from 2.1% to 4.5%, as well as high prevalence of atrial fibrillation ranging from 14.0% to 48.5%. There is a growing interest in evaluating the risk of thromboembolism depending on...
Source: ESC Heart Failure - September 9, 2021 Category: Cardiology Authors: Xiaogang Zhu,
Zhenhua Wang,
Markus W. Ferrari,
Katharina Ferrari ‐Kuehne,
Javed Bulter,
Xiuying Xu,
Quanzhong Zhou,
Yuhui Zhang,
Jian Zhang Tags: Review Source Type: research
Impact of renin ‐angiotensin system inhibitors on long‐term clinical outcomes of patients with rheumatic heart disease
ConclusionRenin –angiotensin–aldosterone system inhibitor treatment was significantly associated with decreased risks of mortality, HF rehospitalization, and new-onset AF in RHD patients in median 5.9 year follow-up.
Source: ESC Heart Failure - September 21, 2021 Category: Cardiology Authors: Cheng Liu,
Yanxian Lai,
Deping Wu,
Ruibin Fu,
Yanfang Li,
Hu Li,
Tianwang Guan,
Yan Shen Tags: Original Research Article Source Type: research
Safety and efficacy of iron supplementation after myocardial infarction in mice with moderate blood loss anaemia
ConclusionsIron supplementation 24 h after reperfusion of AMI is safe and reversed enlargement of end-systolic volume after AMI resulting in increased stroke volume and cardiac output. This highlights its potential as adjunctive treatment in anaemia with ID after reperfused AMI. Time point of iron application after reperfusion appe ars critical.
Source: ESC Heart Failure - October 12, 2021 Category: Cardiology Authors: Patricia Wischmann,
Ramesh Chennupati,
Isabella Solga,
Felix Funk,
Stefanie Becher,
Norbert Gerdes,
Stefan Anker,
Malte Kelm,
Christian Jung Tags: Original Research Article Source Type: research
Mortality risk in chronic Chagas cardiomyopathy: a systematic review and meta ‐analysis
ConclusionsThe annual mortality risk in chronic Chagas cardiomyopathy is substantial and primarily attributable to cardiovascular causes. This risk significantly increases in patients with low left ventricular ejection fraction and those classified as AHA stages C and C/D.
Source: ESC Heart Failure - November 1, 2021 Category: Cardiology Authors: Sindhu Chadalawada,
Anis Rassi,
Omar Samara,
Anthony Monzon,
Deepika Gudapati,
Lilian Vargas Barahona,
Peter Hyson,
Stefan Sillau,
Luisa Mestroni,
Matthew Taylor,
Maria Consola ção Vieira Moreira,
Kristen DeSanto,
Nelson I. Agudelo Higuita, Tags: Original Research Article Source Type: research
Long ‐term impact of β‐blocker in elderly patients without myocardial infarction after percutaneous coronary intervention
ConclusionsLong-term β-blocker use was significantly associated with an increased risk of adverse cardiovascular events in elderly patients with CAD without MI or systolic HF. In particular, the chronotropic incompetence action of β-blockers could increase the risk of admission for HF in elderly patients with CAD with out MI and systolic HF, and the present findings warrant further investigation.
Source: ESC Heart Failure - November 23, 2021 Category: Cardiology Authors: Tatsuya Fukase,
Tomotaka Dohi,
Takuma Koike,
Hidetoshi Yasuda,
Mitsuhiro Takeuchi,
Norihito Takahashi,
Yuichi Chikata,
Hirohisa Endo,
Shinichiro Doi,
Hiroki Nishiyama,
Iwao Okai,
Hiroshi Iwata,
Shinya Okazaki,
Katsumi Miyauchi,
Hiroyuki Daid Tags: Original Article Source Type: research
