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Can Patent Foramen Ovales Cause Problems?
Discussion During fetal development, the heart primum and secundum septa grow and overlap leaving a small but important channel between the two atria. The foramen ovale is a flap valve moving blood from the right atrium into the left atrium directly and bypassing the high pressure pulmonary system. After birth and breathing air, the neonate’s lungs open up and the pulmonary vascular resistance decreases. The left atrium now has a relatively higher pressure than the right atria, and therefore pressure on the flap valve closes the foramen ovale. Usually within 6-12 months, the fusion of the primum and secundum of the f...
Source: PediatricEducation.org - July 24, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Half-Dose Tenecteplase or Primary Percutaneous Coronary Intervention in Older Patients With ST-Segment-Elevation Myocardial Infarction in STREAM-2: A Randomized, Open-Label Trial
CONCLUSIONS: Halving the dose of tenecteplase in a pharmaco-invasive strategy in this early-presenting, older STEMI population was associated with electrocardiographic changes that were at least comparable to those after primary PCI. Similar clinical efficacy and angiographic end points occurred in both treatment groups. The risk of intracranial hemorrhage was higher with half-dose tenecteplase than with primary PCI. If timely PCI is unavailable, this pharmaco-invasive strategy is a reasonable alternative, provided that contraindications to fibrinolysis are observed and excess anticoagulation is avoided.REGISTRATION: URL: ...
Source: Circulation - July 13, 2023 Category: Cardiology Authors: Frans Van de Werf Arsen D Risti ć Oleg V Averkov Alexandra AriasMendoza Yves Lambert Jos é F Kerr Saraiva Pablo Sepulveda Fernando Rosell-Ortiz John K French Ljilja B Musi ć Katleen Vandenberghe Kris Bogaerts Cynthia M Westerhout Alain Pag ès Thierry Source Type: research

More Europeans Died Because of Heat in 2022 Than Any Year in Recorded History
As the Earth continues to warm, the rising temperatures are contributing to a number of health conditions that are in turn driving up mortality. And for the first time, scientists have figured out a more detailed way to estimate how many deaths can be attributed to heat. In a paper published in Nature Medicine, researchers in Spain and France calculated that more than 61,000 deaths in Europe could be blamed on the heat during the summer of 2022, the hottest summer on record for the continent. (At least until the readings from 2023 are analyzed later this year.) [time-brightcove not-tgx=”true”] “We are pro...
Source: TIME: Health - July 10, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized climate change embargoed study healthscienceclimate Source Type: news

Type 2 diabetes and cardiorenal syndromes. A nationwide French hospital cohort study
CONCLUSION: Patients with T2DM represent almost half of patients with CRS and are younger than their non-diabetic counterparts. T2DM doubles the risk of CRS and increases the risk of death, cardiovascular outcome, and end-stage kidney disease but not ischemic stroke after CRS.PMID:36931430 | DOI:10.1016/j.diabet.2023.101441
Source: Diabetes and Metabolism - March 17, 2023 Category: Endocrinology Authors: Valentin Maisons Jean-Michel Halimi Gr égoire Fauchier Jean-Baptiste de Fr éminville Nicolas Goin Juliette Gueguen Philippe Gatault B énédicte Sautenet Denis Angoulvant Julien Herbert Arnaud Bisson Pierre-Henri Ducluzeau Laurent Fauchier Source Type: research

Prevalence and Incidence of Cardiovascular and Renal Diseases in Type 1 Compared with Type 2 Diabetes: A Nationwide French Observational Study of Hospitalized Patients
CONCLUSIONS: Although the crude prevalent burden of CV diseases may be lower in T1DM than in T2DM, patients with T1DM may have a higher risk of incident MI, HF, all-cause death and CV death above 60 years of age, highlighting the need for improved prevention in this population.PMID:36736892 | DOI:10.1016/j.diabet.2023.101429
Source: Diabetes and Metabolism - February 3, 2023 Category: Endocrinology Authors: Pierre Henri Ducluzeau Gr égoire Fauchier Julien Herbert Carl Semaan Jean Michel Halimi Denis Angoulvant Laurent Fauchier Source Type: research

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