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Effects of gut microbial metabolite trimethylamine N-oxide (TMAO) on platelets and endothelial cells.
Abstract Thrombotic events result from different pathologies and are the underlying causes of severe diseases like stroke or myocardial infarction. Recent basic research now revealed a link between food uptake, food conversion and gut metabolism. Gut microbial production of trimethylamine N-oxide (TMAO) from dietary nutrients like choline, lecithin and L-carnitine was associated with the development of cardiovascular diseases. Within this review we give a systematic overview about the influence of TMAO on blood components like platelets and endothelial cells which both are involved as key players in thrombotic pro...
Source: Clinical Hemorheology and Microcirculation - September 6, 2020 Category: Hematology Authors: Krüger-Genge A, Jung F, Hufert F, Jung EM, Küpper JH, Storsberg J Tags: Clin Hemorheol Microcirc Source Type: research

6 Simple Health Tips for Buying Chocolate
Shopping for "good" chocolate is kind of like searching for a viable online date. Approach the market without a plan and it's easy to get duped by glossy packaging and false claims. Know what you're looking for, though, and you can find yourself a sweetie with substance -- guaranteed to reduce your stress levels, ignite your sex life, and make your heart sing from the first blissful encounter. In fact, findings from a new long-term study in Heart journal involving 25,000 volunteers suggest that eating up to 3.5 ounces of high-quality chocolate per day can significantly reduce risks of heart disease and stroke. Sort through...
Source: Healthy Living - The Huffington Post - February 14, 2016 Category: Consumer Health News Source Type: news

Eggs, Also, May Raise Heart Risk Via Gut Bacteria
Yet another study, by the same US research team, links raised risk of heart attack and stroke to the action of gut bacteria on certain compounds contained in digested food. This time the link is to a compound found in eggs: lecithin. Earlier this month, researchers reported in Nature Medicine how they found L-carnitine, a compound found in red meat and added to energy drinks, can increase heart risk because gut bacteria digest it to produce trimethylamine-N-oxide (TMAO), a metabolite already suspected of helping to clog up arteries...
Source: Health News from Medical News Today - April 25, 2013 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news