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A Retrospective Study of Stroke in Women Compared to Men in Outcome and Readmission Causes (P1.216)
Conclusion:This study is among the first to discuss stroke in minority population in the Middle East. We did not identify sex as an important determinant of outcome after an acute ischemic stroke in this study.Disclosure: Dr. AlShaer has nothing to disclose. Dr. Khoja has nothing to disclose. Dr. Rammal has nothing to disclose. Dr. Almekhlafi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: AlShaer, D., Khoja, A., Rammal, S., Almekhlafi, M. Tags: Re-admission and Stroke Outcomes Source Type: research

Comparison of Ventricular Assist Device (VAD)-Related Stroke to the General Stroke Population: Associations with In-Hospital Mortality (P1.223)
Conclusions: Ischemic stroke in patients with VAD is associated with high in-hospital mortality. Although both older patients and women comprised a smaller percentage of VADWS than in the general stroke population, there was no age or sex association with mortality. While pre-existing CAD was more prevalent in VADWS, these patients had lower in-hospital mortality, possibly suggesting an additional unidentified subset with high mortality. Further study is needed to explore the associations between age, sex, and CAD in patients with VAD and ischemic stroke.Disclosure: Dr. Peters has nothing to disclose. Dr. Singh has nothing...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Peters, S., Singh, T., Tirschwell, D. Tags: Cardiac Mechanisms and Complications of Stroke Source Type: research

Pregnancy in Advanced Age Increases the Risk of Hemorrhagic Stroke in Post-Menopausal Women. Analysis of Women's Health Initiative Study (P6.005)
Conclusions: Women with pregnancy in advanced age have a higher risk for hemorrhagic stroke in post-menopausal period.Disclosure: Dr. Qureshi has nothing to disclose. Dr. Saeed has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Degenhardt has nothing to disclose. Dr. Axt-Fliedner has nothing to disclose. Dr. Kohl has nothing to disclose. Dr. Suri has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Qureshi, A., Saeed, O., Malik, A., Degenhardt, J., Axt-Fliedner, R., Kohl, T., Suri, M. Tags: Cerebrovascular Disease and Interventional Neurology Poster Discussion Session Source Type: research

From 'Sweet Clover Disease' to NOACs: A Historical Perspective on Oral Anticoagulation for Prevention of Cardioembolic Stroke (P2.397)
CONCLUSIONS: Warfarin, born from ‘sweet clover disease’ and humble beginnings as rodenticide, has been the cornerstone of cardioembolic stroke prevention. Its shortcomings inspired the development of a new generation of oral anticoagulants.Disclosure: Dr. Chiota-McCollum has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Chiota-McCollum, N. Tags: History of Neurology Source Type: research

Obesity Paradox in Patients Hospitalized for Acute Ischemic Stroke: An Analysis of Nationwide Inpatient Sample Data (S47.008)
Conclusions: Among patients hospitalized for AIS, obese patients had lower risk adjusted in-hospital mortality. Similar trend persisted among IV-tpa and non IV-tpa group. The association of obesity and better prognosis, also known as the "obesity paradox" holds true for AIS. This is the first study of its kind on the largest all payer database. However, further studies are required to establish causal relationship for this phenomenon.Disclosure: Dr. Lunagariya has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Savani has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Jani has nothing to disclose. ...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Lunagariya, A., Patel, A., Savani, C., Patel, U., Jani, V., Hussain, S., Mehta, S. Tags: IV-tPA and Endovascular Therapy Source Type: research

Predictors of In-Hospital Ischemic Stroke During Acute Myocardial Infarction Hospitalizations (P6.043)
CONCLUSIONS: The higher association of increasing age, sex and race with Ischemic stroke is depicted. The patients who undergo by-pass graft procedure are more likely to develop stroke. Therefore, further studies are warranted for improved risk stratification in AMI patients.Disclosure: Dr. Shah has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Bhatia has nothing to disclose. Dr. Jani has nothing to disclose. Dr. Lunagariya has nothing to disclose. Dr. Onteddu has nothing to disclose. Dr. Kassab has nothing to disclose. Dr. Mehta has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Shah, H., Patel, A., Bhatia, P., Jani, V., Lunagariya, A., Onteddu, S., Mishra, P., Kassab, M., Mehta, S. Tags: In-Hospital Stroke and Stroke Complications Source Type: research

Pulmonary Edema as an Adverse Effect in Albumin Treatment for Acute Ischemic Stroke Study (P6.073)
Conclusion: We did not find any significant association of pulmonary edema as an adverse effect with non-pulmonary edema. Further analysis is needed to look for any significant association.Disclosure: Dr. Hussein has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Miran has nothing to disclose. Dr. Saleem has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Hussein, H., Qureshi, I., Miran, M. S., Saleem, M., Qureshi, A. Tags: Cerebrovascular Disease: Miscellaneous Interventions Source Type: research

Natural History of Extracranial Carotid Stenosis in Asian Stroke Patients- A Retrospective Study (P1.182)
Conclusions- Symptomatic steno-occlusive disease of cervical carotid artery carries a high risk of subsequent vascular events and mortality despite best medical therapy. Perhaps, better methods of risk stratification and an aggressive approach towards revascularisation in eligible cases are warranted.Disclosure: Dr. Chandra has nothing to disclose. Dr. Woo has nothing to disclose. Dr. Woo has nothing to disclose. Dr. Liu has nothing to disclose. Dr. Kulkarni has nothing to disclose. Dr. Sharma has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Chandra, B., Woo, J. W., Woo, R. W., Liu, R. J., Kulkarni, A., Sharma, V. Tags: Cerebrovascular Disease: Risk Factors and Prevention Source Type: research

Can CREST Procedural Results Be Reproduced in General Practice in Post CREST Era? Analysis of National Surgical Quality Improvement Program (NSQIP) Registry (S42.001)
Conclusions: Our results support reproducibility of CREST procedural outcomes for both CEA and CAS in general practice in post-trial period.Disclosure: Dr. Jani has nothing to disclose. Dr. Zafar has nothing to disclose. Dr. Afzal has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Jani, V., Zafar, A., Afzal, M., Qureshi, A. Tags: Stroke Mechanism and Modifiers Source Type: research

Elevated FVIII Predicts Subsequent Acute Ischemic Stroke in Patients with Transient Ischemic Attack (S42.004)
CONCLUSIONS: In our sample, eFVIII was associated with increased risk of a subsequent AIS admission. These findings may indicate a greater risk for other future thrombotic events in post-TIA patients with eFVIII and begs the question as to optimal antithrombotic therapy in this population.Disclosure: Dr. Semmes has nothing to disclose. Dr. Monlezun, Jr has nothing to disclose. Dr. Samai has nothing to disclose. Dr. Martin-Schild has received personal compensation for activities with Genentech.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Semmes, E., Monlezun, Jr, D., Samai, A., Martin-Schild, S. Tags: Stroke Mechanism and Modifiers Source Type: research

Household Secondhand Smoke Exposure Confers Higher Stroke Risk and Poorer Stroke Prognosis (S42.005)
CONCLUSIONS: Household SHS is associated with a 1.5-fold increase in stroke risk and a 2-fold increase in mortality after stroke among never-smokers. While prospective studies are needed to assess causality, this study highlights the importance of obtaining SHS exposure history and counseling patients and their families on the potential impact of SHS on post-stroke outcomes.Disclosure: Dr. Lin has nothing to disclose. Dr. Ovbiagele has nothing to disclose. Dr. Markovic has nothing to disclose. Dr. Towfighi has nothing to disclose.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Lin, M., Ovbiagele, B., Markovic, D., Towfighi, A. Tags: Stroke Mechanism and Modifiers Source Type: research

Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke
Conclusions: Our data identify a genetic contribution to inflammatory and hemostatic biomarkers in a stroke population. Additionally, our results suggest shared genetic contributions to circulating CRP levels measured poststroke and risk for incident and recurrent ischemic stroke. These data broaden our understanding of genetic contributors to biomarker variation and ischemic stroke risk, which should be useful in clinical risk evaluation.
Source: Neurology - January 25, 2016 Category: Neurology Authors: Williams, S. R., Hsu, F.-C., Keene, K. L., Chen, W.-M., Nelson, S., Southerland, A. M., Madden, E. B., Coull, B., Gogarten, S. M., Furie, K. L., Dzhivhuho, G., Rowles, J. L., Mehndiratta, P., Malik, R., Dupuis, J., Lin, H., Seshadri, S., Rich, S. S., Sale Tags: All Cerebrovascular disease/Stroke, Case control studies, Risk factors in epidemiology, All Genetics, Association studies in genetics ARTICLE Source Type: research

Long-term use of daily sumatriptan injections in severe drug-resistant chronic cluster headache
Chronic cluster headache (CCH) is a rare but severely debilitating condition.1 Some patients have drug-resistant CCH and continue to have daily attacks using abortive agents for long periods many times per day, mainly subcutaneous sumatriptan (SS).2 According to pharmaceutical company indications, the maximum SS dosage is 2 injections (12 mg) per day but these patients often use more. This limitation appears reasonable because of single case reports of cardiac arrest attributable to SS vasoconstrictive properties.3,4 Usually these events occur at the initial administration, and an underlying occult coronary artery disease ...
Source: Neurology - January 11, 2016 Category: Neurology Authors: Leone, M., Proietti Cecchini, A. Tags: All Headache, Cluster headache, Patient safety CLINICAL/SCIENTIFIC NOTES Source Type: research

Risk of stroke in retinal vein occlusion
Conclusions: The present study provides new evidence that patients with incident RVO are at increased risk of stroke just after RVO occurrence. Immediate risk evaluation and proper treatment of stroke risk factors in patients with RVO are needed to reduce stroke-related mortality and morbidity.
Source: Neurology - November 2, 2015 Category: Neurology Authors: Park, S. J., Choi, N.-K., Yang, B. R., Park, K. H., Woo, S. J. Tags: All Cerebrovascular disease/Stroke, Cardiac, Risk factors in epidemiology ARTICLE Source Type: research

Association of Lp-PLA2-A and early recurrence of vascular events after TIA and minor stroke
Conclusions: Higher levels of Lp-PLA2-A in the acute period are associated with increased short-term risk of recurrent vascular events.
Source: Neurology - November 2, 2015 Category: Neurology Authors: Lin, J., Zheng, H., Cucchiara, B. L., Li, J., Zhao, X., Liang, X., Wang, C., Li, H., Mullen, M. T., Johnston, S. C., Wang, Y., Wang, Y., On behalf of the CHANCE investigators Tags: Other cerebrovascular disease/ Stroke ARTICLE Source Type: research

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