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UArizona researchers launch the Great Arizona Tick Check
As spring blooms across much of the state, University of Arizona researchers are encouraging the public to check for ticks and contribute to an important community health effort.
Rosemary Brandt
Today
College of Agriculture& Life SciencesRhipicephalussanguineus_hires-small.jpg
A male brown dog tick, Rhipicephalus sanguineus. Brown dog ticks are the primary vector for Rocky Mountain spotted fever in Arizona.
CDC/ James GathanyHealthScience and TechnologyCollege of Agriculture and Life SciencesCollege of Public Health
Media contact(s)Rosemary Brandt
College of Agriculture and Life Sciencesrjbrandt@email.arizona...
Source: The University of Arizona: Health - March 17, 2023 Category: Universities & Medical Training Authors: rjbrandt Source Type: research
The Transcriptome of the Salivary Glands of Amblyomma aureolatum Reveals the Antimicrobial Peptide Microplusin as an Important Factor for the Tick Protection Against Rickettsia rickettsii Infection
Conclusion
In conclusion, our data show that R. rickettsii exerts a modulatory effect on the transcriptional profile the SG of A. aureolatum. Moreover, RNAi experiments demonstrated that the knockdown of one microplusin increases the susceptibility of ticks to infection, suggesting that this is one important factor for the control of R. rickettsii. The functional characterization of the additional CDSs modulated by infection is warranted and might reveal other factors that interfere with the acquisition and/or transmission of this tick-borne pathogen.
Ethics Statement
All procedures involving vertebrate animals were car...
Source: Frontiers in Physiology - May 2, 2019 Category: Physiology Source Type: research