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Specialty: Cardiology
Condition: Diabetes Mellitus
Drug: Insulin
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Total 55 results found since Jan 2013.
Do Non-Functional Adrenal Adenomas Affect Metabolic Profile and Carotid Intima-Media Thickness? A Single Centre Study from Poland
Conclusions: Patients diagnosed with NFAIs, despite normal cortisol inhibition in the 1 mg dexamethasone test, still presented a number of metabolic abnormalities. The assessment of IMT may proove valuable in indicate the presence of early vascular remodelling in asymptomatic patients. The underlying mechanisms of these findings are still unknown, hence further studies are required.PMID:37510727 | PMC:PMC10380859 | DOI:10.3390/jcm12144612
Source: Atherosclerosis - July 29, 2023 Category: Cardiology Authors: Magdalena Szychli ńska Magdalena Rzeczkowska Katarzyna Gontarz-Nowak Wojciech Matuszewski El żbieta Bandurska-Stankiewicz Source Type: research
The efficacy and safety of Chinese herbal medicine as an add-on therapy for type 2 diabetes mellitus patients with carotid atherosclerosis: An updated meta-analysis of 27 randomized controlled trials
Conclusion: Based on this meta-analysis, we found that in the treatment of T2DM patients with CAS, combined with CHM may have more advantages than WM alone, which can further reduce CIMT and carotid plaque Crouse score, regulate glucose and lipid metabolism, improve insulin resistance and enhance islet β-cell function. Meanwhile, CHM is relatively safe. However, limited by the quality and heterogeneity of included studies, the efficacy and safety of CHM remain uncertain. More high-quality studies are still needed to provide more reliable evidence for the clinical application of CHM. Systematic Review Registration: https:/...
Source: Atherosclerosis - April 10, 2023 Category: Cardiology Authors: Zehua Zhang Yulin Leng Zhengtao Chen Xiaoxu Fu Qingzhi Liang Xi Peng Hongyan Xie Hong Gao Chunguang Xie Source Type: research
Association of hyperuricemia with cardiovascular diseases: current evidence
Hosp Pract (1995). 2023 Feb 2. doi: 10.1080/21548331.2023.2173413. Online ahead of print.ABSTRACTThe aim of the present study is to present a historical and unified perspective on the association of serum uric acid (SUA) in the cause cardiovascular diseases (CVDs). The association of hyperuricemia (HUC) with CVD begun to be appreciated in the middle 1950s and early 1990s when clinical evidence was shown on the association of HUC with CVD. However, this association was disputed by several investigators including the Framingham group and by professional societies, like the American Heart Association and the American Society ...
Source: Atherosclerosis - February 2, 2023 Category: Cardiology Authors: Steven G Chrysant Source Type: research
The role of miRNAs in insulin resistance and diabetic macrovascular complications - A review
Int J Biol Macromol. 2023 Jan 6:123189. doi: 10.1016/j.ijbiomac.2023.123189. Online ahead of print.ABSTRACTDiabetes is the most prevalent metabolic disturbance disease and has been regarded globally as one of the principal causes of mortality. Diabetes is accompanied by several macrovascular complications, including stroke, coronary artery disease (CAD), and cardiomyopathy as a consequence of atherosclerosis. The onset of type 2 diabetes is closely related to insulin resistance (IR). miRNAs have been linked to various metabolic processes, including glucose homeostasis, regulation of lipid metabolism, gluconeogenesis, adipo...
Source: Atherosclerosis - January 9, 2023 Category: Cardiology Authors: Sherif S Abdel Mageed Ahmed S Doghish Ahmed Ismail Ahmed A El-Husseiny Sylvia F Fawzi Abdulla M A Mahmoud Hesham A El-Mahdy Source Type: research
How dysregulation of the immune system promotes diabetes mellitus and cardiovascular risk complications
Front Cardiovasc Med. 2022 Sep 29;9:991716. doi: 10.3389/fcvm.2022.991716. eCollection 2022.ABSTRACTDiabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin resistance or failure to produce insulin. Patients with DM develop microvascular complications that include chronic kidney disease and retinopathy, and macrovascular complications that mainly consist in an accelerated and more severe atherosclerosis compared to the general population, increasing the risk of cardiovascular (CV) events, such as stroke or myocardial infarction by 2- to 4-fold. DM is commonly associate...
Source: Atherosclerosis - October 17, 2022 Category: Cardiology Authors: Diane Girard Claire Vandiedonck Source Type: research
Crosstalk between neurological, cardiovascular, and lifestyle disorders: insulin and lipoproteins in the lead role
Pharmacol Rep. 2022 Sep 23. doi: 10.1007/s43440-022-00417-5. Online ahead of print.ABSTRACTInsulin resistance and impaired lipoprotein metabolism contribute to a plethora of metabolic and cardiovascular disorders. These alterations have been extensively linked with poor lifestyle choices, such as consumption of a high-fat diet, smoking, stress, and a redundant lifestyle. Moreover, these are also known to increase the co-morbidity of diseases like Type 2 diabetes mellitus and atherosclerosis. Under normal physiological conditions, insulin and lipoproteins exert a neuroprotective role in the central nervous system. However, ...
Source: Atherosclerosis - September 23, 2022 Category: Cardiology Authors: Richa Tyagi Bhupesh Vaidya Shyam Sunder Sharma Source Type: research
Causal Association of Type 2 Diabetes Mellitus and Glycemic Traits With Cardiovascular Diseases and Lipid Traits: A Mendelian Randomization Study
CONCLUSION: We provided evidence for the causal effects of T2DM and glycemic traits on the risk of CVDs and dyslipidemia. Further investigations to elucidate the underlying mechanisms are warranted.PMID:35528012 | PMC:PMC9072667 | DOI:10.3389/fendo.2022.840579
Source: Atherosclerosis - May 9, 2022 Category: Cardiology Authors: Mingkai Huang Loum-Davadi Laina-Nicaise Lingfeng Zha Tingting Tang Xiang Cheng Source Type: research
Diabetes and Ischemic Stroke: An Old and New Relationship an Overview of the Close Interaction between These Diseases
Int J Mol Sci. 2022 Feb 21;23(4):2397. doi: 10.3390/ijms23042397.ABSTRACTDiabetes mellitus is a comprehensive expression to identify a condition of chronic hyperglycemia whose causes derive from different metabolic disorders characterized by altered insulin secretion or faulty insulin effect on its targets or often both mechanisms. Diabetes and atherosclerosis are, from the point of view of cardio- and cerebrovascular risk, two complementary diseases. Beyond shared aspects such as inflammation and oxidative stress, there are multiple molecular mechanisms by which they feed off each other: chronic hyperglycemia and advanced...
Source: Atherosclerosis - February 26, 2022 Category: Cardiology Authors: Carlo Domenico Maida Mario Daidone Gaetano Pacinella Rosario Luca Norrito Antonio Pinto Antonino Tuttolomondo Source Type: research
Short- and Long-term cardiovascular outcomes in insulin-treated versus non-insulin-treated diabetes mellitus patients after percutaneous coronary intervention: a systematic review and meta-analysis
CONCLUSION: Despite a tremendous technical success rate of multi-vessel stenting, people living with diabetes who were being treated with insulin had higher long-term, and short-term mortality rates, MI, TLR, TVR, and stroke compared to people living with diabetes who were being treated with means other than insulin and are more prone to detrimental cardiovascular outcomes.PMID:34906538 | DOI:10.1016/j.ihj.2021.12.004
Source: Indian Heart J - December 15, 2021 Category: Cardiology Authors: Wardah Hassan Javeria Saquib Mahima Khatri Syeda Kanza Kazmi Sohny Kotak Hani Hassan Jawad Ahmed Source Type: research
