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Source: Neurology
Condition: Dementia

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Total 240 results found since Jan 2013.

Endovascular treatment improves cognition after stroke: A secondary analysis of REVASCAT trial
Conclusions: Thrombectomy improves TMT performance after stroke, especially among patients who reach good functional recovery. ClinicalTrials.gov identifier: NCT01692379. Classification of evidence: This study provides Class I evidence that for patients with stroke from acute anterior circulation proximal arterial occlusion, thrombectomy improves performance on the TMT at 3 months.
Source: Neurology - January 15, 2017 Category: Neurology Authors: Lopez-Cancio, E., Jovin, T. G., Cobo, E., Cerda, N., Jimenez, M., Gomis, M., Hernandez-Perez, M., Caceres, C., Cardona, P., Lara, B., Renu, A., Llull, L., Boned, S., Muchada, M., Davalos, A. Tags: Prognosis, All Cerebrovascular disease/Stroke, Clinical trials Randomized controlled (CONSORT agreement), Infarction ARTICLE Source Type: research

A quantitative systematic review of domain-specific cognitive impairment in lacunar stroke
Conclusions: Results of this systematic review are consistent with previous characterizations of cognitive impairment associated with lacunar strokes. However, impaired cognition in this stroke subtype appears less selective than previously thought, involving all major cognitive domains.
Source: Neurology - January 14, 2013 Category: Neurology Authors: Edwards, J. D., Jacova, C., Sepehry, A. A., Pratt, B., Benavente, O. R. Tags: Other cerebrovascular disease/ Stroke, Clinical neurology examination, Neuropsychological assessment, Assessment of cognitive disorders/dementia VIEWS & amp;amp; REVIEWS Source Type: research

Incidence of stroke in people with Alzheimer disease: A national register-based approach
Conclusions: Our findings suggest that persons with AD dementia, especially younger patients, have higher risk of hemorrhagic strokes.
Source: Neurology - January 21, 2013 Category: Neurology Authors: Tolppanen, A.-M., Lavikainen, P., Solomon, A., Kivipelto, M., Soininen, H., Hartikainen, S. Tags: All Cerebrovascular disease/Stroke, Alzheimer's disease, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

White matter lesion volume reduces fine motor skills: Is primary stroke prophylaxis warranted?
Neuroimaging, particularly cerebral MRI, frequently demonstrates white matter lesions (WMLs) in the elderly and patients with vascular risk factors such as arterial hypertension and diabetes. WMLs may result from ischemia associated with atherosclerosis of perforating arteries and arteriolar degeneration due to fibrohyalinosis.1,2 They can appear silently, but are an important risk factor for the development of stroke, mainly ischemic stroke.3 Moreover, WMLs are linked to the development of cognitive impairment and dementia.4,5
Source: Neurology - May 11, 2015 Category: Neurology Authors: Wartenberg, K. E., Lorenzano, S. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Vascular dementia, Prevalence studies, Risk factors in epidemiology EDITORIALS Source Type: research

Cognitive performance and poor long-term functional outcome after young stroke
Conclusions: On average, 11 years after young IS there was no clear relationship between long-term cognitive deficits and long-term functional outcome or IADL, stressing the need for further prospective studies with further development of sensitive measures of functional prognosis.
Source: Neurology - August 31, 2015 Category: Neurology Authors: Synhaeve, N. E., Schaapsmeerders, P., Arntz, R. M., Maaijwee, N. A. M., Rutten-Jacobs, L. C. A., Schoonderwaldt, H. C., Dorresteijn, L. D. A., de Kort, P. L. M., van Dijk, E. J., Kessels, R. P. C., de Leeuw, F.-E. Tags: Stroke in young adults, Prognosis, Assessment of cognitive disorders/dementia ARTICLE Source Type: research

Rate of Endovascular Therapy in Octogenarian/Nonagenarian Acute Ischemic Stroke Patients Compared to Younger Patients (I2.007)
Conclusions: Frequency of EVT and IV-TPA use in AIS patients 蠅80years are increasing but rates remain significantly lower compared with younger patients. Disparity in EVT use in octogenarian/nonagenarian also exists by race and hospital factors. Targeted efforts are needed to lessen this disparity.Disclosure: Dr. Otite has nothing to disclose. Dr. Khandelwal has nothing to disclose. Dr. Tipirneni has nothing to disclose. Dr. Fellman has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Yavagal has received personal compensation for activities with Covidien/evV3 as a consultant and Steering Committee Member...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Otite, F., Khandelwal, P., Tipirneni, A., Fellman, M., Malik, A., Yavagal, D., Chaturvedi, S. Tags: Stroke in the Elderly and Young: Challenges for the Next Decade Data Blitz Presentations Source Type: research

Thrombolysis for acute ischemic stroke in patients with leukoaraiosis: Caution needed
The term leukoaraiosis (LA), introduced about 30 years ago,1 describes cerebral white matter signal abnormalities (or white matter hyperintensities) commonly observed on structural brain magnetic resonance or CT imaging in elderly individuals. LA severity can be graded using categorical classification, based on different rating scales,2 or continuously, using automatic quantification algorithms. LA has multiple histopathologic correlates, including ependymal loss, cerebral ischemia, demyelination, venous collagenosis, and microcystic infarcts.3 A substantial body of evidence now supports associations between LA and increas...
Source: Neurology - February 12, 2017 Category: Neurology Authors: Streifler, J., Maillard, P. Tags: All Cerebrovascular disease/Stroke, Clinical trials Systematic review/meta analysis, Infarction, Intracerebral hemorrhage EDITORIALS Source Type: research

Predicting long term cognitive outcomes after stroke using pre and post-stroke cognitive trajectories. (P2.098)
Conclusions:The rate of decline in cognition after stroke is predicted by rate of decline prior to stroke. Furthermore, greater change in rate of cognitive decline after incident stroke predicts dementia in individuals who were normal at the time of stroke. This may be a marker of both ongoing cerebrovascular injury and underlying neurodegenerative pathology.Disclosure: Dr. Thomas has nothing to disclose. Dr. Mattek has nothing to disclose. Dr. Wild has nothing to disclose. Dr. Dodge has nothing to disclose. Dr. Silbert has received research support from Eli-Lilly. Dr. Kaye has received personal compensation for activities...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Thomas, N., Mattek, N., Wild, K., Dodge, H., Silbert, L., Kaye, J., Erten-Lyons, D. Tags: Vascular Disease and Dementia Source Type: research

The association of sleep apnea and stroke with cognitive performance: the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study (I9-4B)
CONCLUSIONS These results suggest that S+SA is associated with lower verbal memory and executive function scores (but not highest global cognitive impairment) than SA only, stroke only, or neither.Disclosure: Dr. Molano has nothing to disclose. Dr. Kleindorfer has received personal compensation for activities with Genentech. Dr. McClure has received research support from Genzyme and Amgen. Dr. Unverzagt has received personal compensation for activities with Eli Lilly & Company as a consultant. Dr. Wadley has received personal compensation for activities with Amgen Inc. Dr. Howard has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Molano, J., Kleindorfer, D., McClure, L., Unverzagt, F., Wadley, V., Howard, V. Tags: Treating Dementia in an Age of Mixed Disease Data Blitz Presentations Source Type: research

Stroke risk factors, post stroke anxiety and neurocognitive function (s36.003)
Conclusions:As in other contexts, the prevalence of clinically significant anxiety after stroke in this low income population is high. It is frequently co-morbid with depression and associated with cognitive impairment in stroke survivors.Study Supported by:National Institute of Neurological Disorders and Stroke (NINDS-U01 NS079179) and GACD.Disclosure: Dr. Owolabi has nothing to disclose. Dr. Akinyemi has nothing to disclose. Dr. Akinyemi has nothing to disclose. Dr. Gebregziabher has nothing to disclose. Dr. Uvere has nothing to disclose. Dr. Ovbiagele has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Owolabi, M., Akinyemi, R., Akinyemi, J., Gebregziabher, M., Uvere, E., Ovbiagele, B. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology Source Type: research

Temporal and Racial Trends in Post-Stroke Dementia in the "Stroke Buckle" of the United States (P1.099)
CONCLUSIONS: Over the last decade, incidence of PSD significantly increased in South Carolina. Black stroke patients had higher overall rates of PSD than whites, but this difference was largely driven by a comparatively greater burden of Non-AD dementia. Since Non-AD dementia is predominantly composed of vascular dementia, better vascular risk factor control may help bridge this racial disparity.Disclosure: Dr. Boan has nothing to disclose. Dr. Lackland has nothing to disclose. Dr. Feng has nothing to disclose. Dr. Voeks has nothing to disclose. Dr. Adams has received personal compensation for activities with Reach Call In...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Boan, A., Lackland, D., Feng, W., Voeks, J., Adams, R., Bachman, D., Ovbiagele, B. Tags: Neuroepidemiology: Aging and Dementia, Epilepsy, and Education Source Type: research

Probable rapid eye movement sleep behavior disorder and risk of stroke: a prospective study (P4.302)
Conclusions:Presence of pRBD was associated with a higher risk of developing stroke, including both ischemic and hemorrhagic types. Future studies with clinically confirmed RBD and a longer follow-up would be appropriate to further investigate this association.Study Supported by: The National Institute of Neurological Disorders And Stroke at the National Institutes of Health (NINDS 5R21NS087235-02 to X.G.)Disclosure: Dr. Ma has nothing to disclose. Dr. Pavlova has received research support from Lundbeck and Biomobie Corporation. Dr. Liu has nothing to disclose. Dr. Liu has nothing to disclose. Dr. Huangfu has nothing to di...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ma, C., Pavlova, M., Liu, Y., Liu, Y., Huangfu, C., Wu, S., Gao, X. Tags: Neuroepidemiology: Cerebrovascular Disease I Source Type: research

Triage in Stroke Units: Physicians Perceptions and Ethical Issues (P02.008)
CONCLUSIONS: Despite a vocation to take care of all patients, triage practices are pointed out during stroke unit admission. They depend on the role of each physician in the acute stroke management. They are the integration of a distributive justice theory, of contextual data, but also of subjective clinician evaluation. The triage decisions are ineluctable because of the scarcity of resource but are complex and difficult to take for clinicians, because they face to the "rule of rescue". These medical choices involve also the values of the society.Disclosure: Dr. Yger has nothing to disclose. Dr. Crozier has nothing to dis...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Yger, M., Crozier, S., Dubourdieu, S., Vivien, B., Dolveck, F., Samson, Y. Tags: P02 Ethics, Pain, and Palliative Care Source Type: research

Olfactory and Gustatory Dysfunction and Subsequent Stroke Risk: A Community-Based Cohort Study (P1.107)
CONCLUSIONS: Olfactory and gustatory dysfunction was associated with increased short-term future risks of stroke. Further studies with larger sample size and objective measures of olfactory and gustatory function are warranted to confirm our findings.Disclosure: Dr. Ma has nothing to disclose. Dr. Huang has nothing to disclose. Dr. Wu has nothing to disclose. Dr. Yuan has nothing to disclose. Dr. He has nothing to disclose. Dr. Chen has nothing to disclose. Dr. Wu has nothing to disclose. Dr. Gao has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Ma, C., Huang, Z., Wu, Z., Yuan, X., He, S., Chen, S., Wu, S., Gao, X. Tags: Neuroepidemiology: Cerebrovascular Disease Source Type: research

Stroke Outcome, Functionality and Health Care Resource Utilization among Elderly (P02.024)
CONCLUSIONS: Identifying factors that impact stroke outcome, may reduce unwanted investigations, decrease the length of hospital stay and lead to proper utilization of hospital resources which in turn could be used for improvement in the functional state of patients.Disclosure: Dr. Samavedam has nothing to disclose. Dr. Naughton has nothing to disclose. Dr. Ravi has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Samavedam, S., Naughton, B., Ravi, V. Tags: P02 Cerebrovascular Disease II Source Type: research