Filtered By:
Condition: Autoimmune Disease
Drug: Acetylcysteine
This page shows you your search results in order of date.
Order by Relevance | Date
Total 45 results found since Jan 2013.
Autophagy dysregulation in trichloroethene-mediated inflammation and autoimmune response
Toxicology. 2023 Feb 26;487:153468. doi: 10.1016/j.tox.2023.153468. Online ahead of print.ABSTRACTTrichloroethene (TCE), an organic solvent extensively used for degreasing metals, can cause inflammatory autoimmune disorders [i.e., systemic lupus erythematosus (SLE) and autoimmune hepatitis] from both environmental and occupational exposure. Autophagy has emerged as a pivotal pathogenic factor in various autoimmune diseases. However, role of autophagy dysregulation in TCE-mediated autoimmunity is largely unknown. Here, we investigate whether autophagy dysregulation contributes to pathogenesis of TCE-mediated autoimmune resp...
Source: Toxicology - February 27, 2023 Category: Toxicology Authors: Hui Wang Nivedita Banerjee Gangduo Wang M Firoze Khan Source Type: research
Study of the Effects of N-acetylcysteine on Inflammatory Biomarkers and Disease Activity Score in Patients with Rheumatoid Arthritis
Iran J Allergy Asthma Immunol. 2021 Sep 28;20(5):574-583. doi: 10.18502/ijaai.v20i5.7407.ABSTRACTRheumatoid arthritis (RA) is considered as an autoimmune-related condition in which the overproduction of pro-inflammatory cytokines leads to an inflammatory cascade. N-acetylcysteine (NAC) is a potent anti-inflammatory and anti-oxidant agent. We aimed to explore the impact of oral NAC on cytokines activities and clinical indicators in RA patients. In this placebo-controlled randomized double-blind clinical trial, 41 active RA patients were allocated in either NAC (600 mg, twice a day) or placebo group, as add-on therapy to the...
Source: Iranian Journal of Allergy, Asthma and Immunology - October 19, 2021 Category: Allergy & Immunology Authors: Faezeh Jamali Arman Ahmadzadeh Zahra Sahraei Jamshid Salamzadeh Source Type: research
