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MELAS Syndrome: How Stroke-like are the Stroke episodes? (P1.255)
Conclusions:Patients with MELAS syndrome may present with recurrent strokes in the arterial territory rather than SLEs. Clinicians should entertain the possibility of a mitochondrial disease in young patients with cryptogenic stroke and pursue appropriate diagnostic evaluations and treatment.Disclosure: Dr. Liaw has nothing to disclose. Dr. Lewis has nothing to disclose. Dr. Saini has nothing to disclose. Dr. Gultekin has nothing to disclose. Dr. Koch has nothing to disclose. Dr. Asdaghi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Liaw, N., Lewis, R., Saini, V., Gultekin, S. H., Koch, S., Asdaghi, N. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

The Spectrum of Aphasia Subtypes and Etiology in Subacute Stroke
Background: Aphasia is one of the most common stroke syndrome presentations, yet little is known about the spectrum of different subtypes or their stroke mechanisms. Yet, subtypes and etiology are known to influence the prognosis and recovery.Aim: Our aim is to analyze aphasia subtypes and etiology in a large subacute stroke population.Methods: Consecutive patients from a dedicated cognitive stroke registry were accrued. A validated cognitive screening examination was administered during the first month of stroke presentation, which enabled a diagnosis of 14 different aphasic subtypes. The evolution from one subtype to ano...
Source: Journal of Stroke and Cerebrovascular Diseases - May 15, 2013 Category: Neurology Authors: Michael Hoffmann, Ren Chen Tags: Original Articles Source Type: research

Ischemic stroke in a patient with Parry-Romberg syndrome (P4.064)
Conclusions:The only other reported patient with PRS and stroke was also found to have a PFO. It is possible that the elevated ANA seen in this patient correlates with propensity towards small venous clots not seen on ultrasound. This may lead to paradoxical emboli and ischemic strokes. It is important to note this potential association between PRS and ischemic stroke in young patients without other known risk factors. It would be worthwhile to treat this subset of patients with medications for secondary stroke prevention.Disclosure: Dr. Ebiana has nothing to disclose. Dr. Singh has nothing to disclose. Dr. Khosa has nothi...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ebiana, V., Singh, S., Khosa, S., Moheb, N., Trikamji, B., Rao, N., Mishra, S. Tags: General Neurology: Vascular Neurology Source Type: research

Evaluation of Clinico-radiological, Molecular and Histological Diagnosis of m.3243A>G-related MELAS Syndrome (P2.259)
CONCLUSIONS: Our data suggest that SLE phenomenology is much more uniform than purported in the literature. These findings highlights the importance of a comprehensive clinical examination including detailed visual field evaluation and consideration of m.3243A>G in all cases of stroke and encephalopathy irrespective of age, gender or family pedigree with an unrecognised high recurrence rate within first year of initial presentation. Aggressive mangement of seizure is advocated to prevent ensuing SLE. Study Supported by:Disclosure: Dr. Ng has nothing to disclose. Dr. Gorman has nothing to disclose. Dr. Schaefer has nothi...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ng, Y. S., Gorman, G., Schaefer, A., Taylor, R., McFarland, R., Turnbull, D. Tags: Cerebrovascular Disease and Interventional Neurology: Genetics and Stroke Source Type: research

Musical hallucinations with a right frontotemporal stroke.
This report discusses some of the possible mechanisms for this patient's presentation. Although the mechanism of his musical hallucinations remains unclear, recognition of this uncommon syndrome is important when structuring rehabilitation and management for patients with stroke who have this disorder. PMID: 32930641 [PubMed - as supplied by publisher]
Source: Neurocase - September 14, 2020 Category: Neurology Authors: Buchwald N, Kelly A, Heilman KM, Simpkins AN Tags: Neurocase Source Type: research

Pure word deafness due to bilateral temporal lobe ischemic stroke occurring at different time points over the years: a case report on the insight of brain language network reorganization
Neurocase. 2021 Mar 9:1-7. doi: 10.1080/13554794.2021.1896744. Online ahead of print.ABSTRACTHere we present a case of a native Greek male patient who presented clinically with sudden onset pure word deafness after an ischemic stroke in the temporoparietal region of the right hemisphere, but who had suffered an ischemic stroke 9 years previously in an adjacent area of the left hemisphere, causing aphasic symptoms which resolved quickly and almost completely. What makes this case interesting and novel is that it is the first case describing a patient whose ventral language comprehension circuit did not reorganize successful...
Source: Neurocase - March 9, 2021 Category: Neurology Authors: Ioanna-Eleni Virvidaki Lambros Messinis Grigorios Nasios Source Type: research

Acute Hearing Loss Caused by Decreasing Anterior Inferior Cerebellar Arterial Perfusion in a Patient with Vertebral Artery Stenosis
We report a case of bilateral hearing loss caused by decreased vascular flow in the anterior inferior cerebellar artery (AICA) territory. A 74-year-old man who experienced right hearing loss 5 months ago presented with bilateral deafness and right cerebellar ataxia; however, no ischemic lesion was detected in the bilateral AICA area. After stroke treatment, hearing loss was improved. One month later, we obtained blood flow improvement in the left AICA territory on single –photon-emission computed tomography and vertebral artery stenosis on magnetic resonance angiography.
Source: Journal of Stroke and Cerebrovascular Diseases - March 31, 2017 Category: Neurology Authors: Rintaro Fukuda, Nobukazu Miyamoto, Arisa Hayashida, Yuji Ueno, Kazuo Yamashiro, Ryota Tanaka, Nobutaka Hattori Tags: Case Studies Source Type: research

Pure word deafness in a patient with bilateral ischemic stroke in the superior temporal gyrus (STG).
Conclusions: Our case suggested that bilateral, symmetric lesions in the region of STG could cause pure world deafness. The diversity and severity of symptoms confirm the necessity of pure world deafness classification for subtypes. PMID: 32364009 [PubMed - as supplied by publisher]
Source: Neurocase - May 1, 2020 Category: Neurology Authors: Slotwinski K, Ejma M, Szczepanska A, Budrewicz S, Koszewicz M Tags: Neurocase Source Type: research

Cortical deafness of following bilateral temporal lobe stroke
Cortical deafness is an extremely rare clinical manifestation that originates mainly from bilateral cortical lesions in the primary auditory cortex. Its main clinical manifestation is the bilateral sudden loss of hearing. Diagnosis is difficulty due to its rarity and similarity with other language and communication disorders, such as Wernicke's aphasia, auditory agnosia or verbal deafness. Herein, we present a case report of a young woman with a sudden bilateral loss of auditory comprehension. Initially, a psychiatric nature of the disorder was considered, but the persistence of the symptoms, lead to the diagnosis of corti...
Source: Journal of Stroke and Cerebrovascular Diseases - May 5, 2020 Category: Neurology Authors: J úlia Silva, Marisa Sousa, Susana Mestre, Isa Nzwalo, Hipólito Nzwalo Tags: Case Report Source Type: research

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