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Time trends for risk of severe age-related diseases in individuals with and without HIV infection in Denmark: a nationwide population-based cohort study
Publication date: Available online 27 May 2015 Source:The Lancet HIV Author(s): Line D Rasmussen , Margaret T May , Gitte Kronborg , Carsten S Larsen , Court Pedersen , Jan Gerstoft , Niels Obel Background Whether the reported high risk of age-related diseases in HIV-infected people is caused by biological ageing or HIV-associated risk factors such as chronic immune activation and low-grade inflammation is unknown. We assessed time trends in age-standardised and relative risks of nine serious age-related diseases in a nationwide cohort study of HIV-infected individuals and population controls. Methods We identified all ...
Source: The Lancet HIV - May 28, 2015 Category: Infectious Diseases Source Type: research

The Role of Decision Aids in Depression Care
Clarion calls about enhancing detection and management of depression in primary care have reiterated several truisms: Depression is as prevalent as many common medical disorders, treatable yet frequently undertreated, responsible for enormous occupational and social impairment as well as adverse effects on the costs, treatment outcomes, and mortality of comorbid medical diseases. Depression is second only to low back pain in years lived with disability (YLD), a metric that incorporates disease prevalence, age of onset, chronicity, and impairment. The YLDs attributable to depression exceed those accounted for by diabetes, i...
Source: JAMA Internal Medicine - September 28, 2015 Category: Internal Medicine Source Type: research

The growing burden of noncommunicable disease among persons living with HIV in Zimbabwe
Conclusion: NCD services will need to be expanded in Zimbabwe. They will need to be integrated into HIV care programmes, although the growing NCD burden amongst uninfected individuals presenting opportunities for additional services developed within HIV care to benefit HIV-negative persons.
Source: AIDS - March 16, 2018 Category: Infectious Diseases Tags: Epidemiology and Social Source Type: research