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Outcome after intracranial hemorrhage under dabigatran and reversal with idarucizumab versus under vitamin-K-antagonists – the RIC-ICH study
ConclusionThese results, based on data from routine clinical practice, suggest that in-hospital mortality after idarucizumab treatment is comparable to that in patients pretreated with VKA. Due to the low precision of estimates, the results must be interpreted with caution.
Source: Frontiers in Neurology - July 24, 2023 Category: Neurology Source Type: research

Start, Stop, Continue? The Benefit of Overlapping Intravenous Thrombolysis and Mechanical Thrombectomy
ConclusionThe presented results support the approach of continuing and completing a  simultaneous administration of intravenous thrombolysis during mechanical thrombectomy procedures.
Source: Clinical Neuroradiology - July 26, 2022 Category: Neurology Source Type: research

Interdisciplinary neurovascular networks: state of the art.
CONCLUSION: The certification process of NVN has been successfully established and the audits proved to be a useful instrument for quality control and improvement. The 15 NVN are highly efficient and treat more than one quarter of stroke patients in German stroke units. PMID: 32930814 [PubMed - as supplied by publisher]
Source: Der Nervenarzt - September 14, 2020 Category: Neurology Authors: Röther J, Busse O, Berlis A, Dörfler A, Groden C, Hamann G, Jansen O, Meixensberger J, Müller O, Regelsberger J, Steinmetz H, Vatter H, Weber W, Nabavi D Tags: Nervenarzt Source Type: research

Coagulation disorders in Duchenne muscular dystrophy? Results of a registry-based online survey.
Authors: Schorling DC, Müller CK, Pechmann A, Borell S, Langer T, Thiele S, Walter MC, Zieger B, Kirschner J Abstract Different complications of hemostasis have been reported in patients with Duchenne Muscular Dystrophy (DMD). These comprise an increased rate of bleeding-symptoms during scoliosis surgery but also thromboembolic complications such as pulmonary embolism, cerebral infarction, deep vein thrombosis or cardiac thrombus. For this cross-sectional study, personalized online survey-links were forwarded to 682 registered patients with a genetically confirmed diagnosis of DMD via the German-Austrian DMD patie...
Source: Acta Myologica - July 3, 2020 Category: Neurology Tags: Acta Myol Source Type: research

EP.69Disorders of coagulation in Duchenne muscular dystrophy? Results of a registry-based online survey
Several types of coagulation disorders are reported in patients with Duchenne muscular dystrophy (DMD). Those include repeated reports of increased rate of bleeding-complications following scoliosis surgery but also reports of thromboembolic complications. Personalized survey-links were forwarded to 682 registered patients with a genetically confirmed diagnosis of DMD via the German DMD-registry of the Treat-NMD-network. Data on the degree of mobility, disposition to hematoma, epistaxis and gum bleeding, occurrence of postsurgical hemorrhage, stroke, deep vein thrombosis, cardiac thromboembolism, long-term medication and a...
Source: Neuromuscular Disorders - September 30, 2019 Category: Neurology Authors: D. Schorling, C. M üller, A. Pechmann, S. Borell, T. Langer, S. Thiele, M. Walter, B. Zieger, J. Kirschner Source Type: research

Associations of Anemia With Outcomes in Patients With Spontaneous Intracerebral Hemorrhage: A Meta-Analysis
Conclusions: Anemia on admission was associated with higher mortality and an increased risk of poor outcome in patients with ICH. However, the results were limited by the high heterogeneity of included studies. Prospective, multi-center or population-based, large sample cohort studies are needed in the future. Introduction Intracerebral hemorrhage (ICH) is the second most common cause of stroke and a highly lethal disease (1), which still lacks effective therapeutic interventions (2, 3). Although age, baseline ICH volume and neurological status on admission are well-known predictors of outcome of ICH (4), none of t...
Source: Frontiers in Neurology - April 24, 2019 Category: Neurology Source Type: research

Frequency of Hemorrhage on Follow Up Imaging in Stroke Patients Treated With rt-PA Depending on Clinical Course
Conclusions: Frequency of hemorrhagic transformation in Routine follow-up brain imaging and consecutive changes in therapeutic management were different depending on clinical course measured by NHISS score. Introduction Brain imaging 24–36 h after systemic thrombolysis for acute ischemic stroke is recommended in American Stroke Association and European Stroke Organization guidelines (1, 2). Brain imaging is performed to detect secondary bleeding or hemorrhagic transformation in order to adapt medical stroke prevention if necessary. Guideline recommendations are based on the results of the first study on rt-PA...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research