Filtered By:
Condition: Asthma
Nutrition: Calcium
This page shows you your search results in order of date.
Order by Relevance | Date
Total 199 results found since Jan 2013.
Melatonin reduces exo-endocytosis in mast cells, making it a useful therapeutic tool in inflammatory diseases
Mast cells were previously known for their role in the type I hypersensitivity responses of the Gell and Coombs 1963 classification, where they are activated by immune complexes, FcRI – IgE – allergens, on their cell surface. However, the function of mast cells is much broader than hypersensitivity, being considered tissue sentinels of the immune system1. Many other stimuli, such as IgG, TLR, neuropeptides, cytokines, or chemicals such as compound 48/80 or PMACI [PMA (phorbol 12-myristate 13-acetate) plus CI (calcium ionophore A23187)] can trigger the selective release of vasoactive mediators and stimulate proliferatio...
Source: Annals of Allergy, Asthma and Immunology - August 7, 2023 Category: Allergy & Immunology Authors: Mar ía Dolores Maldonado, María Carmen Gutiérrez-Pérez, Juan Antonio Flores, Eva Ales Tags: Letters Source Type: research
Exercise Reduces Airway Smooth Muscle Contraction in Asthmatic Rats via Inhibition of IL-4 Secretion and Store-Operated Ca < sup > 2+ < /sup > Entry Pathway
CONCLUSIONS: The data in this study reveal that aerobic exercise may improve the ASM contractile function in asthmatic rats by inhibiting IL-4 secretion and by down-regulating the expression of STIM1, Orai1 and Orai2, thus decreasing excessive SOCE-mediated ASM contraction in asthmatic rats.PMID:37075798
Source: Allergy, Asthma and Immunology Research - April 19, 2023 Category: Allergy & Immunology Authors: Jun-Hao Huang Hui-Wen Gao Dong-Dong Gao Wei-Yue Yang Meng-Ke Zhao Bing Shen Min Hu Source Type: research
Oleanolic Acid Acetate Inhibits Mast Cell Activation in Ovalbumin-Induced Allergic Airway Inflammation
CONCLUSIONS: Our study showed that OAA can inhibit mast cell-mediated allergic reaction. Consequently, the application of OAA to mast cells for the allergic airway inflammation facilitate a new direction of treating allergic asthma.PMID:37021507 | DOI:10.4168/aair.2023.15.2.214
Source: Allergy, Asthma and Immunology Research - April 6, 2023 Category: Allergy & Immunology Authors: Yeon-Yong Kim Soyoung Lee Min-Jong Kim Mun-Chual Rho Yong Hyun Jang Sang-Hyun Kim Source Type: research
