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Condition: Chronic Obstructive Pulmonary
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Total 1666 results found since Jan 2013.
Assessment of adherence and asthma medication ratio (AMR) for a once-daily and twice-daily inhaled corticosteroid/long acting beta agonist (ICS/LABA) for asthma
ConclusionsAdherence and treatment persistence were low in both cohorts, however, patients initiating once-daily FF/VI were more likely to be adherent, have an AMR ≥0.5, and were less likely to discontinue therapy compared with patients initiating twice-daily BUD/F. (GSK Study HO1617302/206482)
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 11, 2019 Category: Allergy & Immunology Source Type: research
Beneficial Effect of Early Intervention with Garenoxacin for Bacterial Infection-Induced Acute Exacerbation of Bronchial Asthma and Chronic Obstructive Pulmonary Disease
Conclusion: GRNX effectively treated asthma and COPD patients with acute bacterial infection without severe adverse events. Further research with a larger study population is needed.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - February 14, 2019 Category: Allergy & Immunology Source Type: research
Asthma-COPD overlap - a discordance between patient populations defined by different diagnostic criteria
ConclusionsThe current ACO definitions identify distinct populations which share only a small number of common features and present with different disease phenotypes. ACO prevalence is highly variable, depending on the definition applied.
Source: The Journal of Allergy and Clinical Immunology: In Practice - April 27, 2019 Category: Allergy & Immunology Source Type: research
Assessment of Adherence and Asthma Medication Ratio for a Once-Daily and Twice-Daily Inhaled Corticosteroid/Long-Acting β-Agonist for Asthma
ConclusionsAdherence and treatment persistence were low in both cohorts; however, patients initiating once-daily FF/VI were more likely to be adherent, have an AMR of greater than or equal to 0.5, and were less likely to discontinue therapy compared with patients initiating twice-daily BUD/F (GlaxoSmithKline Study HO1617302/206482).
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 9, 2019 Category: Allergy & Immunology Source Type: research
CME Exam: T2 Biologics for Chronic Obstructive Pulmonary Disease
Publication date: May–June 2019Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 7, Issue 5Author(s):
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 9, 2019 Category: Allergy & Immunology Source Type: research
T2 Biologics for Chronic Obstructive Pulmonary Disease
Publication date: May–June 2019Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 7, Issue 5Author(s): Ahmed Yousuf, Wadah Ibrahim, Neil J. Greening, Christopher E. BrightlingChronic obstructive pulmonary disease (COPD) is a significant cause of morbidity and mortality worldwide. In contrast to other chronic diseases, COPD is increasing in prevalence and is projected to be the third leading cause of death and disability worldwide by 2030. Recent advances in understanding the underlying pathophysiology of COPD has led to the development of novel targeted therapies (biologics and small molecules) t...
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 9, 2019 Category: Allergy & Immunology Source Type: research
Small Airway Dysfunction by Impulse Oscillometry in Symptomatic Patients with Preserved Pulmonary Function
ConclusionPatients with respiratory symptoms and PPF may have SAD that can be identified with the aid of IOS in addition to spirometry.
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 11, 2019 Category: Allergy & Immunology Source Type: research
Asthma-COPD Overlap—A Discordance Between Patient Populations Defined by Different Diagnostic Criteria
ConclusionsThe current ACO definitions identify distinct populations that share only a small number of common features and present with different disease phenotypes. ACO prevalence is highly variable, depending on the definition applied.
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 5, 2019 Category: Allergy & Immunology Source Type: research
The relationship between real-world inhaled corticosteroids adherence and asthma outcomes: a multilevel approach
ConclusionsPatients may adapt their ICS use to their current needs without this impacting later RDAC.
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 19, 2019 Category: Allergy & Immunology Source Type: research
Personalised biofeedback on inhaler adherence and technique by community pharmacists, a cluster randomised clinical trial
ConclusionCommunity pharmacist-delivered inhaler training informed by a digital technology improved adherence and health status.
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 29, 2019 Category: Allergy & Immunology Source Type: research
Determinants and differences in satisfaction with the inhaler among patients with asthma or COPD.
ConclusionsAge, disease control, and training in inhalation technique all play a more significant role than the specific diagnosis in explaining satisfaction with the device in patients with asthma and COPD. These findings underscore the need to provide better training and more active monitoring of inhalation technique to improve patient satisfaction, treatment adherence, and clinical outcomes.
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 5, 2019 Category: Allergy & Immunology Source Type: research
Personalized Biofeedback on Inhaler Adherence and Technique by Community Pharmacists: A Cluster Randomized Clinical Trial
ConclusionsCommunity pharmacist–delivered inhaler training informed by a digital technology improved adherence and health status.
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 13, 2019 Category: Allergy & Immunology Source Type: research
The Relationship Between Real-World Inhaled Corticosteroid Adherence and Asthma Outcomes: A Multilevel Approach
ConclusionsPatients may adapt their ICS use to their current needs without this impacting later RDAC.
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 13, 2019 Category: Allergy & Immunology Source Type: research
Determinants and Differences in Satisfaction with the Inhaler Among Patients with Asthma or COPD
ConclusionsAge, disease control, and training in inhalation technique all play a more significant role than the specific diagnosis in explaining satisfaction with the device in patients with asthma and COPD. These findings underscore the need to provide better training and more active monitoring of the inhalation technique to improve patient satisfaction, treatment adherence, and clinical outcomes.
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 24, 2019 Category: Allergy & Immunology Source Type: research
Asthma-COPD overlap and chronic airflow obstruction: definitions, management, and unanswered questions
We describe the potential benefits of existing asthma and COPD therapies in treating ACO patients, and the value of a “treatable traits” approach to ACO management. Throughout the review, we highlight some of the pressing, unanswered questions surrounding ACO that are relevant to the clinical community. Ultimately, addressing these questions is necessary if we are to improve clinical outcomes for this complex and heterogenous patient population.
Source: The Journal of Allergy and Clinical Immunology: In Practice - November 17, 2019 Category: Allergy & Immunology Source Type: research
