• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Steroid responsive encephalopathy associated with autoimmune thyroiditis (SREAT) with stroke like symptoms. A case report. (P5.104)
Conclusion: Clinicians should consider SREAT in the differential diagnosis of patients presenting with stroke like symptoms/vasculitis especially if investigations fail to establish a diagnosis.Disclosure: Dr. Javalkar has nothing to disclose. Dr. Abbas has nothing to disclose. Dr. Harris has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Javalkar, V., Abbas, S., Harris, M. Tags: Edema, Encephalopathy, and Encephalitis Source Type: research

A Rare Presentation of Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) as Acute Ischemic Stroke (P6.112)
CONCLUSIONS: This case illustrates not only a classic clinical and radiographic case of CLIPPERS, but also that this recently recognized disorder can be easily misdiagnosed as a neuromuscular disease in the early stages, and stroke in the more severe stages. Rarely, the inflammatory infiltrate can result in stroke in these patients, and is likely the cause of the acute exacerbation of our patient’s symptoms. This case also demonstrates the need for contrast imaging whenever possible, as the non-contrast imaging failed to identify the characteristic diffuse enhancing punctate lesions.Disclosure: Dr. Gadhia has nothing...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Gadhia, R., Smith, S., Lai, E., Lee, A. Tags: MS and CNS Inflammatory Disease: CNS Inflammatory Diseases and Differential Diagnosis Source Type: research

An Unusual Cause Of Recurrent Ischemic Stroke: Trousseau's Syndrome From Gastric Cancer (P4.231)
CONCLUSIONS: Trousseau’s Syndrome must be considered in those presenting with recurrent strokes with an otherwise negative embolic work up especially in the elderly and those with cancer risk factors. It must prompt the clinician to look for an associated malignancy.Disclosure: Dr. JADEJA has nothing to disclose. Dr. Johnson has nothing to disclose. Dr. Soetanto has nothing to disclose. Dr. Nalleballe has nothing to disclose. Dr. DeNiro has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Graber has received personal compensation for activities with Stemedica Inc., Novocure Inc., and Biogen Idec.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Jadeja, N., Johnson, J., Soetanto, A., Nalleballe, K., DeNiro, L., Qureshi, I., Graber, J. Tags: Neuro-oncology: Paraneoplastic Disorders Source Type: research

Primary Central Nervous System Vasculitis Triggered by Cytomegalovirus Encephalitis (P01.231)
CONCLUSIONS: Our case is the first reported case in the literature of proven CMV encephalitis triggering a subsequent non-infectious CNS vasculitis probably secondary to an autoimmune response. The absence of findings in the initial MRIs of the brain in spite of an intermittently symptomatic patient and the subsequent development of ischemic infarcts supports the theory of intermittent focal hypoperfusion, finally leading to infarction. The high clinical suspicion even with lack of clear evidence of the disease process and empirical treatment led to a successful clinical recovery.Disclosure: Dr. Rosales has nothing to disc...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Rosales, D., Garcia-Gracia, C., Salgado, E., Salanga, V. Tags: P01 Cerebrovascular Disease I Source Type: research

Granulomatous angiitis of the CNS revealing a Hodgkin lymphoma
Apart from the iatrogenic effects of treatment, neurologic complications of Hodgkin lymphoma (HL) can be divided into direct (meningeal or intracranial/spinal localization) and indirect (paraneoplastic/immune complications).1 Here, we present a patient with granulomatous angiitis of the CNS (GANS) associated with HL that dramatically improved after the treatment of the angiitis by cyclophosphamide, methylprednisolone, and specific chemotherapy.
Source: Neurology - January 14, 2013 Category: Neurology Authors: Le Guennec, L., Roos-Weil, D., Mokhtari, K., Chauvet, D., Psimaras, D., Reiner, P., Demeret, S., Bolgert, F., Choquet, S., Weiss, N. Tags: MRI, Other cerebrovascular disease/ Stroke, All Medical/Systemic disease, Coma, All Oncology, Class IV CLINICAL/SCIENTIFIC NOTES Source Type: research

Voltage Gated Calcium Channels Antibody-Associated Autoimmune Encephalitis (P5.228)
ConclusionThis case demonstrates a correlation between a high titer of VGCC antibodies and autoimmune encephalitis. Our patient's initial improvement with steroids and plasma exchange in the face of a negative CT and PET suggests a primary autoimmune process rather than a paraneoplastic etiology, though we admit that it is premature to rule out remission and we will continue to follow herDisclosure: Dr. Alwaki has nothing to disclose. Dr. Lugo has nothing to disclose. Dr. Goshgarian has nothing to disclose. Dr. Ahmad has nothing to disclose. Dr. Hefzy has nothing to disclose. Dr. Mitsias has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Alwaki, A., Lugo, A., Goshgarian, C., Ahmad, O., Hefzy, H., Mitsias, P. Tags: Aging, Dementia, and Cognitive and Behavioral Neurology: Creutzfeldt-Jakob Disease and Subacute Encephalopathies Source Type: research

Limbic Encephalitis Exacerbations and Remissions Charted by Microglial PET Scan: A Case Study (P4.104)
CONCLUSIONS: C-11-PK11195 PET imaging can be useful in the diagnosis of limbic encephalitis and for monitoring response to treatment. MALT lymphoma may also be associated with autoimmune or paraneoplastic encephalitis, especially in individuals with other predisposing factors to autoimmune disorders, such as Tourette’s and autoimmune thyroid disease. The reduction in microglial activity with both IVIG and anti-psychotics supports previous findings that anti-psychotics may act through anti-inflammatory pathways.Disclosure: Dr. Shatz has received research support from Janssen Pharmaceutica. Dr. Chugani has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Shatz, R., Chugani, H. Tags: Aging, Dementia, Cognitive, and Behavioral Neurology: Rapidly Progressive and Inflammatory Dementias Source Type: research

The Evaluation and Management of Alternative Diagnoses in Amyotrophic Lateral Sclerosis (P5.091)
Conclusions: Treatment with intravenous steroids, immunoglobulin and surgical interventions prior to diagnosis of ALS is associated with a significantly prolonged mean ODI.Disclosure: Dr. Kannan has nothing to disclose. Dr. Glass has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kannan, M., Glass, J. Tags: Neuroepidemiology: Neuro-oncology and ALS Source Type: research

Teaching NeuroImages: Posterior reversible encephalopathy syndrome resulting in hydrocephalus
A woman with prior lung transplantation presented with headaches, seizure, and obtundation. Head MRI (figure) revealed obstructive hydrocephalus and hyperintensity on T2-weighted imaging in the bilateral thalami and brainstem. Management included antiepileptic medications, ventriculostomy placement, and cessation of tacrolimus for concern of atypical posterior reversible encephalopathy syndrome (PRES). Infectious and paraneoplastic etiologies were ruled out. An autoimmune process was unlikely due to immunosuppression. There was rapid clinical improvement with repeat MRI revealing resolution of hydrocephalus and T2 changes....
Source: Neurology - June 5, 2016 Category: Neurology Authors: Paolini, S., Jadhav, A. P. Tags: Hydrocephalus, Secondary headache disorders, Other cerebrovascular disease/ Stroke RESIDENT AND FELLOW SECTION Source Type: research

Fatal Atypical Progressive Multifocal Leukoencephalopathy (PML) in an African American Female with Sarcoidosis Associated Lymphopenia (SAL). A Rare Case Report and Literature Review. (P2.317)
Conclusions:This is the first case of SAL presenting with medullary PML in an African-American patient not on immunosuppressive therapy. The role of SAL in PML pathogenesis or Sarcoidosis Associated Immunodeficiency is unclear. No guidelines for CD4/CD8 monitoring are available and needs further investigation. We suggest an aggressive diagnostic approach in evaluating Sarcoidosis with atypical neurologic manifestations and neuroimaging to reduce morbidity-mortality.Study Supported by: Not applicable.Disclosure: Dr. Rathore has nothing to disclose. Dr. Sweiss has nothing to disclose. Dr. Campanella has nothing to disclose. ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Rathore, J., Sweiss, N., Campanella, F., Andreoni, J., Wichter, M. Tags: HIV, HTLV-I, PML, Other Viral Infections, and CJD Source Type: research