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Cancer: Hepatocellular Carcinoma

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Long non-coding RNA UPK1A-AS1 promotes glycolysis in hepatocellular carcinoma cells < em > via < /em > stabilization of HIF-1 < em > α < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Feb 25;41(2):193-199. doi: 10.12122/j.issn.1673-4254.2021.02.05.ABSTRACTOBJECTIVE: To investigate the effect of long non-coding RNA UPK1A-AS1 on glycolysis of hepatocellular carcinoma cells and its underlying molecular mechanisms.OBJECTIVE: A hepatocellular carcinoma (HCC) cell line with lentivirus-mediated stable UPK1A-AS1 overexpression and the cells infected with a negative control lentiviral vector were cultured under normoxic (21% O2) or hypoxic (1% O2) conditions for 24 h. The effect of UPK1A-AS1 overexpression on glycolysis of the HCC cells was examined. The expressions of glycoly...
Source: Journal of Southern Medical University - February 24, 2021 Category: Universities & Medical Training Authors: D Zhang X Zou Y Song D Wu Source Type: research

Applicability and prognostic value of frailty assessment tools among hospitalized patients with advanced chronic liver disease
CONCLUSION: Frailty assessment using the evaluated tools is feasible among hospitalized cirrhotic patients, identifying those with worse prognosis. CFS had the highest applicability and accuracy for the initial assessment and LFI for the initial and follow-up assessments.PMID:33660956 | PMC:PMC7976891 | DOI:10.3325/cmj.2021.62.8
Source: Croatian Medical Journal - March 4, 2021 Category: General Medicine Authors: Lubomir Skladany Zuzana Drotarova Janka Vnencakova Daniela Jancekova Pavol Molcan Tomas Koller Source Type: research

Long non-coding RNA UPK1A-AS1 promotes glycolysis in hepatocellular carcinoma cells < em > via < /em > stabilization of HIF-1 < em > α < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Feb 25;41(2):193-199. doi: 10.12122/j.issn.1673-4254.2021.02.05.ABSTRACTOBJECTIVE: To investigate the effect of long non-coding RNA UPK1A-AS1 on glycolysis of hepatocellular carcinoma cells and its underlying molecular mechanisms.OBJECTIVE: A hepatocellular carcinoma (HCC) cell line with lentivirus-mediated stable UPK1A-AS1 overexpression and the cells infected with a negative control lentiviral vector were cultured under normoxic (21% O2) or hypoxic (1% O2) conditions for 24 h. The effect of UPK1A-AS1 overexpression on glycolysis of the HCC cells was examined. The expressions of glycoly...
Source: Journal of Southern Medical University - February 24, 2021 Category: Universities & Medical Training Authors: D Zhang X Zou Y Song D Wu Source Type: research

Applicability and prognostic value of frailty assessment tools among hospitalized patients with advanced chronic liver disease
CONCLUSION: Frailty assessment using the evaluated tools is feasible among hospitalized cirrhotic patients, identifying those with worse prognosis. CFS had the highest applicability and accuracy for the initial assessment and LFI for the initial and follow-up assessments.PMID:33660956 | PMC:PMC7976891 | DOI:10.3325/cmj.2021.62.8
Source: Croatian Medical Journal - March 4, 2021 Category: General Medicine Authors: Lubomir Skladany Zuzana Drotarova Janka Vnencakova Daniela Jancekova Pavol Molcan Tomas Koller Source Type: research

Long non-coding RNA UPK1A-AS1 promotes glycolysis in hepatocellular carcinoma cells < em > via < /em > stabilization of HIF-1 < em > α < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Feb 25;41(2):193-199. doi: 10.12122/j.issn.1673-4254.2021.02.05.ABSTRACTOBJECTIVE: To investigate the effect of long non-coding RNA UPK1A-AS1 on glycolysis of hepatocellular carcinoma cells and its underlying molecular mechanisms.OBJECTIVE: A hepatocellular carcinoma (HCC) cell line with lentivirus-mediated stable UPK1A-AS1 overexpression and the cells infected with a negative control lentiviral vector were cultured under normoxic (21% O2) or hypoxic (1% O2) conditions for 24 h. The effect of UPK1A-AS1 overexpression on glycolysis of the HCC cells was examined. The expressions of glycoly...
Source: Journal of Southern Medical University - February 24, 2021 Category: Universities & Medical Training Authors: D Zhang X Zou Y Song D Wu Source Type: research

Applicability and prognostic value of frailty assessment tools among hospitalized patients with advanced chronic liver disease
CONCLUSION: Frailty assessment using the evaluated tools is feasible among hospitalized cirrhotic patients, identifying those with worse prognosis. CFS had the highest applicability and accuracy for the initial assessment and LFI for the initial and follow-up assessments.PMID:33660956 | PMC:PMC7976891 | DOI:10.3325/cmj.2021.62.8
Source: Croatian Medical Journal - March 4, 2021 Category: General Medicine Authors: Lubomir Skladany Zuzana Drotarova Janka Vnencakova Daniela Jancekova Pavol Molcan Tomas Koller Source Type: research

Long non-coding RNA UPK1A-AS1 promotes glycolysis in hepatocellular carcinoma cells < em > via < /em > stabilization of HIF-1 < em > α < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Feb 25;41(2):193-199. doi: 10.12122/j.issn.1673-4254.2021.02.05.ABSTRACTOBJECTIVE: To investigate the effect of long non-coding RNA UPK1A-AS1 on glycolysis of hepatocellular carcinoma cells and its underlying molecular mechanisms.OBJECTIVE: A hepatocellular carcinoma (HCC) cell line with lentivirus-mediated stable UPK1A-AS1 overexpression and the cells infected with a negative control lentiviral vector were cultured under normoxic (21% O2) or hypoxic (1% O2) conditions for 24 h. The effect of UPK1A-AS1 overexpression on glycolysis of the HCC cells was examined. The expressions of glycoly...
Source: Journal of Southern Medical University - February 24, 2021 Category: Universities & Medical Training Authors: D Zhang X Zou Y Song D Wu Source Type: research

Applicability and prognostic value of frailty assessment tools among hospitalized patients with advanced chronic liver disease
CONCLUSION: Frailty assessment using the evaluated tools is feasible among hospitalized cirrhotic patients, identifying those with worse prognosis. CFS had the highest applicability and accuracy for the initial assessment and LFI for the initial and follow-up assessments.PMID:33660956 | PMC:PMC7976891 | DOI:10.3325/cmj.2021.62.8
Source: Croatian Medical Journal - March 4, 2021 Category: General Medicine Authors: Lubomir Skladany Zuzana Drotarova Janka Vnencakova Daniela Jancekova Pavol Molcan Tomas Koller Source Type: research

Long non-coding RNA UPK1A-AS1 promotes glycolysis in hepatocellular carcinoma cells < em > via < /em > stabilization of HIF-1 < em > α < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Feb 25;41(2):193-199. doi: 10.12122/j.issn.1673-4254.2021.02.05.ABSTRACTOBJECTIVE: To investigate the effect of long non-coding RNA UPK1A-AS1 on glycolysis of hepatocellular carcinoma cells and its underlying molecular mechanisms.OBJECTIVE: A hepatocellular carcinoma (HCC) cell line with lentivirus-mediated stable UPK1A-AS1 overexpression and the cells infected with a negative control lentiviral vector were cultured under normoxic (21% O2) or hypoxic (1% O2) conditions for 24 h. The effect of UPK1A-AS1 overexpression on glycolysis of the HCC cells was examined. The expressions of glycoly...
Source: Journal of Southern Medical University - February 24, 2021 Category: Universities & Medical Training Authors: D Zhang X Zou Y Song D Wu Source Type: research

Applicability and prognostic value of frailty assessment tools among hospitalized patients with advanced chronic liver disease
CONCLUSION: Frailty assessment using the evaluated tools is feasible among hospitalized cirrhotic patients, identifying those with worse prognosis. CFS had the highest applicability and accuracy for the initial assessment and LFI for the initial and follow-up assessments.PMID:33660956 | PMC:PMC7976891 | DOI:10.3325/cmj.2021.62.8
Source: Croatian Medical Journal - March 4, 2021 Category: General Medicine Authors: Lubomir Skladany Zuzana Drotarova Janka Vnencakova Daniela Jancekova Pavol Molcan Tomas Koller Source Type: research

Long non-coding RNA UPK1A-AS1 promotes glycolysis in hepatocellular carcinoma cells < em > via < /em > stabilization of HIF-1 < em > α < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Feb 25;41(2):193-199. doi: 10.12122/j.issn.1673-4254.2021.02.05.ABSTRACTOBJECTIVE: To investigate the effect of long non-coding RNA UPK1A-AS1 on glycolysis of hepatocellular carcinoma cells and its underlying molecular mechanisms.OBJECTIVE: A hepatocellular carcinoma (HCC) cell line with lentivirus-mediated stable UPK1A-AS1 overexpression and the cells infected with a negative control lentiviral vector were cultured under normoxic (21% O2) or hypoxic (1% O2) conditions for 24 h. The effect of UPK1A-AS1 overexpression on glycolysis of the HCC cells was examined. The expressions of glycoly...
Source: Journal of Southern Medical University - February 24, 2021 Category: Universities & Medical Training Authors: D Zhang X Zou Y Song D Wu Source Type: research

Applicability and prognostic value of frailty assessment tools among hospitalized patients with advanced chronic liver disease
CONCLUSION: Frailty assessment using the evaluated tools is feasible among hospitalized cirrhotic patients, identifying those with worse prognosis. CFS had the highest applicability and accuracy for the initial assessment and LFI for the initial and follow-up assessments.PMID:33660956 | PMC:PMC7976891 | DOI:10.3325/cmj.2021.62.8
Source: Croatian Medical Journal - March 4, 2021 Category: General Medicine Authors: Lubomir Skladany Zuzana Drotarova Janka Vnencakova Daniela Jancekova Pavol Molcan Tomas Koller Source Type: research

Long non-coding RNA UPK1A-AS1 promotes glycolysis in hepatocellular carcinoma cells < em > via < /em > stabilization of HIF-1 < em > α < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Feb 25;41(2):193-199. doi: 10.12122/j.issn.1673-4254.2021.02.05.ABSTRACTOBJECTIVE: To investigate the effect of long non-coding RNA UPK1A-AS1 on glycolysis of hepatocellular carcinoma cells and its underlying molecular mechanisms.OBJECTIVE: A hepatocellular carcinoma (HCC) cell line with lentivirus-mediated stable UPK1A-AS1 overexpression and the cells infected with a negative control lentiviral vector were cultured under normoxic (21% O2) or hypoxic (1% O2) conditions for 24 h. The effect of UPK1A-AS1 overexpression on glycolysis of the HCC cells was examined. The expressions of glycoly...
Source: Journal of Southern Medical University - February 24, 2021 Category: Universities & Medical Training Authors: D Zhang X Zou Y Song D Wu Source Type: research