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Cancer: Hepatocellular Carcinoma

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Prediction of microvascular invasion in hepatocellular carcinoma with magnetic resonance imaging using models combining deep attention mechanism with clinical features
CONCLUSION: The fusion models based on multiple MRI sequences can effectively detect MVI in patients with HCC, demonstrating the validity of deep learning algorithm that combines attention mechanism and clinical features for MVI grade prediction.PMID:37313827 | DOI:10.12122/j.issn.1673-4254.2023.05.21
Source: Journal of Southern Medical University - June 14, 2023 Category: Universities & Medical Training Authors: G Gong S Cao H Xiao W Fang Y Que Z Liu C Chen Source Type: research

A perianal subcutaneous metastasis as the presenting sign for lung cancer
We report a case of a 77-year-old white man who presented with a 9-day history of a painful, rapidly growing mass on his left buttock in the gluteal cleft. The deep dermal location of the neoplasm and the lack of epidermal involvement led to suspicion of a metastatic carcinoma. Imaging showed a lung lesion suspected to be a primary malignancy with distant liver and gastric fundus metastases. Lung pathology showed primarily adenocarcinoma with squamous differentiation, whereas the skin biopsy showed poorly differentiated squamous cell carcinoma. Clinically, we concluded the skin carcinoma was a metastasis of a primary lung ...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Aaminah Azhar Elizabeth Wilder Source Type: research

Long non-coding RNA UPK1A-AS1 promotes glycolysis in hepatocellular carcinoma cells < em > via < /em > stabilization of HIF-1 < em > α < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Feb 25;41(2):193-199. doi: 10.12122/j.issn.1673-4254.2021.02.05.ABSTRACTOBJECTIVE: To investigate the effect of long non-coding RNA UPK1A-AS1 on glycolysis of hepatocellular carcinoma cells and its underlying molecular mechanisms.OBJECTIVE: A hepatocellular carcinoma (HCC) cell line with lentivirus-mediated stable UPK1A-AS1 overexpression and the cells infected with a negative control lentiviral vector were cultured under normoxic (21% O2) or hypoxic (1% O2) conditions for 24 h. The effect of UPK1A-AS1 overexpression on glycolysis of the HCC cells was examined. The expressions of glycoly...
Source: Journal of Southern Medical University - February 24, 2021 Category: Universities & Medical Training Authors: D Zhang X Zou Y Song D Wu Source Type: research

A perianal subcutaneous metastasis as the presenting sign for lung cancer
We report a case of a 77-year-old white man who presented with a 9-day history of a painful, rapidly growing mass on his left buttock in the gluteal cleft. The deep dermal location of the neoplasm and the lack of epidermal involvement led to suspicion of a metastatic carcinoma. Imaging showed a lung lesion suspected to be a primary malignancy with distant liver and gastric fundus metastases. Lung pathology showed primarily adenocarcinoma with squamous differentiation, whereas the skin biopsy showed poorly differentiated squamous cell carcinoma. Clinically, we concluded the skin carcinoma was a metastasis of a primary lung ...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Aaminah Azhar Elizabeth Wilder Source Type: research

Long non-coding RNA UPK1A-AS1 promotes glycolysis in hepatocellular carcinoma cells < em > via < /em > stabilization of HIF-1 < em > α < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Feb 25;41(2):193-199. doi: 10.12122/j.issn.1673-4254.2021.02.05.ABSTRACTOBJECTIVE: To investigate the effect of long non-coding RNA UPK1A-AS1 on glycolysis of hepatocellular carcinoma cells and its underlying molecular mechanisms.OBJECTIVE: A hepatocellular carcinoma (HCC) cell line with lentivirus-mediated stable UPK1A-AS1 overexpression and the cells infected with a negative control lentiviral vector were cultured under normoxic (21% O2) or hypoxic (1% O2) conditions for 24 h. The effect of UPK1A-AS1 overexpression on glycolysis of the HCC cells was examined. The expressions of glycoly...
Source: Journal of Southern Medical University - February 24, 2021 Category: Universities & Medical Training Authors: D Zhang X Zou Y Song D Wu Source Type: research

A perianal subcutaneous metastasis as the presenting sign for lung cancer
We report a case of a 77-year-old white man who presented with a 9-day history of a painful, rapidly growing mass on his left buttock in the gluteal cleft. The deep dermal location of the neoplasm and the lack of epidermal involvement led to suspicion of a metastatic carcinoma. Imaging showed a lung lesion suspected to be a primary malignancy with distant liver and gastric fundus metastases. Lung pathology showed primarily adenocarcinoma with squamous differentiation, whereas the skin biopsy showed poorly differentiated squamous cell carcinoma. Clinically, we concluded the skin carcinoma was a metastasis of a primary lung ...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Aaminah Azhar Elizabeth Wilder Source Type: research

Long non-coding RNA UPK1A-AS1 promotes glycolysis in hepatocellular carcinoma cells < em > via < /em > stabilization of HIF-1 < em > α < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Feb 25;41(2):193-199. doi: 10.12122/j.issn.1673-4254.2021.02.05.ABSTRACTOBJECTIVE: To investigate the effect of long non-coding RNA UPK1A-AS1 on glycolysis of hepatocellular carcinoma cells and its underlying molecular mechanisms.OBJECTIVE: A hepatocellular carcinoma (HCC) cell line with lentivirus-mediated stable UPK1A-AS1 overexpression and the cells infected with a negative control lentiviral vector were cultured under normoxic (21% O2) or hypoxic (1% O2) conditions for 24 h. The effect of UPK1A-AS1 overexpression on glycolysis of the HCC cells was examined. The expressions of glycoly...
Source: Journal of Southern Medical University - February 24, 2021 Category: Universities & Medical Training Authors: D Zhang X Zou Y Song D Wu Source Type: research

A perianal subcutaneous metastasis as the presenting sign for lung cancer
We report a case of a 77-year-old white man who presented with a 9-day history of a painful, rapidly growing mass on his left buttock in the gluteal cleft. The deep dermal location of the neoplasm and the lack of epidermal involvement led to suspicion of a metastatic carcinoma. Imaging showed a lung lesion suspected to be a primary malignancy with distant liver and gastric fundus metastases. Lung pathology showed primarily adenocarcinoma with squamous differentiation, whereas the skin biopsy showed poorly differentiated squamous cell carcinoma. Clinically, we concluded the skin carcinoma was a metastasis of a primary lung ...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Aaminah Azhar Elizabeth Wilder Source Type: research

Long non-coding RNA UPK1A-AS1 promotes glycolysis in hepatocellular carcinoma cells < em > via < /em > stabilization of HIF-1 < em > α < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Feb 25;41(2):193-199. doi: 10.12122/j.issn.1673-4254.2021.02.05.ABSTRACTOBJECTIVE: To investigate the effect of long non-coding RNA UPK1A-AS1 on glycolysis of hepatocellular carcinoma cells and its underlying molecular mechanisms.OBJECTIVE: A hepatocellular carcinoma (HCC) cell line with lentivirus-mediated stable UPK1A-AS1 overexpression and the cells infected with a negative control lentiviral vector were cultured under normoxic (21% O2) or hypoxic (1% O2) conditions for 24 h. The effect of UPK1A-AS1 overexpression on glycolysis of the HCC cells was examined. The expressions of glycoly...
Source: Journal of Southern Medical University - February 24, 2021 Category: Universities & Medical Training Authors: D Zhang X Zou Y Song D Wu Source Type: research

A perianal subcutaneous metastasis as the presenting sign for lung cancer
We report a case of a 77-year-old white man who presented with a 9-day history of a painful, rapidly growing mass on his left buttock in the gluteal cleft. The deep dermal location of the neoplasm and the lack of epidermal involvement led to suspicion of a metastatic carcinoma. Imaging showed a lung lesion suspected to be a primary malignancy with distant liver and gastric fundus metastases. Lung pathology showed primarily adenocarcinoma with squamous differentiation, whereas the skin biopsy showed poorly differentiated squamous cell carcinoma. Clinically, we concluded the skin carcinoma was a metastasis of a primary lung ...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Aaminah Azhar Elizabeth Wilder Source Type: research

Long non-coding RNA UPK1A-AS1 promotes glycolysis in hepatocellular carcinoma cells < em > via < /em > stabilization of HIF-1 < em > α < /em >
Nan Fang Yi Ke Da Xue Xue Bao. 2021 Feb 25;41(2):193-199. doi: 10.12122/j.issn.1673-4254.2021.02.05.ABSTRACTOBJECTIVE: To investigate the effect of long non-coding RNA UPK1A-AS1 on glycolysis of hepatocellular carcinoma cells and its underlying molecular mechanisms.OBJECTIVE: A hepatocellular carcinoma (HCC) cell line with lentivirus-mediated stable UPK1A-AS1 overexpression and the cells infected with a negative control lentiviral vector were cultured under normoxic (21% O2) or hypoxic (1% O2) conditions for 24 h. The effect of UPK1A-AS1 overexpression on glycolysis of the HCC cells was examined. The expressions of glycoly...
Source: Journal of Southern Medical University - February 24, 2021 Category: Universities & Medical Training Authors: D Zhang X Zou Y Song D Wu Source Type: research