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Cancer: Squamous Cell Carcinoma

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Prevention and management of esophageal stricture after esophageal ESD: 10 years of experience in a single medical center
CONCLUSION: Esophageal stricture is frequently encountered in esophageal ESD. Aggressive preventative strategy is warranted for the high-risk group. Endoscopy/luminal management has high efficacy for post-ESD esophageal stricture.PMID:36572585 | DOI:10.1016/j.jfma.2022.12.006
Source: J Formos Med Assoc - December 26, 2022 Category: General Medicine Authors: Wen-Hung Hsu Hsiang-Yao Shih Chun-Sheng Shen Fang-Jung Yu Hui-Ching Wang Leong-Perng Chan Chao-Hung Kuo Hui-Min Hsieh I-Chen Wu Source Type: research

Abstract B102: NSCLC observations combining medical charts and administrative claims data
Conclusions: Based on analysis of chart data, the NSCLC algorithm for claims data did not effectively exclude SCLC. NSCLC would be expected in 85% of cases and SCLC in 10-15% of all lung cancers, yet the algorithm developed to select NSCLC yielded a sample with about 21% SCLC. Claims data allow for a fairly comprehensive view of a large number of patients, but important information is not available, such as a distinction between NSCLC and SCLC. Medical record data enable greater depth of patient and tumor characteristics, but missing data may be common due to less restrictive reporting standards and because reporting is no...
Source: Molecular Cancer Therapeutics - January 7, 2016 Category: Cancer & Oncology Authors: Schwab, P., MacLean, E., Chioda, M., Moll, K., Pasquale, M., Mardekian, J., Futch, T. Tags: Molecular Classification of Tumors: Poster Presentations - Proffered Abstracts Source Type: research

Hiatal hernia repair and magnetic sphincter augmentation to treat laryngopharyngeal reflux aiding the prevention of recurrent laryngeal cancer
We present a patient with a squamous cell cancer of the larynx who was diagnosed with gastroesophageal reflux disease (GERD) and found to have LPR. The cancer was treated locally and GERD was eradicated with magnetic sphincter augmentation. After 15 months of follow-up, there was no residual cancer. This case highlights the role that untreated LPR may play in patients' risk of developing laryngeal cancer.PMID:33456181 | PMC:PMC7785177 | DOI:10.1080/08998280.2020.1818167
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Madeline Smoot Marc A Ward Lindsey Arviso Christine E Sanchez Steven G Leeds Source Type: research

A perianal subcutaneous metastasis as the presenting sign for lung cancer
We report a case of a 77-year-old white man who presented with a 9-day history of a painful, rapidly growing mass on his left buttock in the gluteal cleft. The deep dermal location of the neoplasm and the lack of epidermal involvement led to suspicion of a metastatic carcinoma. Imaging showed a lung lesion suspected to be a primary malignancy with distant liver and gastric fundus metastases. Lung pathology showed primarily adenocarcinoma with squamous differentiation, whereas the skin biopsy showed poorly differentiated squamous cell carcinoma. Clinically, we concluded the skin carcinoma was a metastasis of a primary lung ...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Aaminah Azhar Elizabeth Wilder Source Type: research

Spontaneous tumor lysis syndrome in squamous cell carcinoma of the lung
Proc (Bayl Univ Med Cent). 2020 Sep 28;34(1):128-130. doi: 10.1080/08998280.2020.1818911.ABSTRACTTumor lysis syndrome (TLS) is an oncologic emergency, more commonly occurring in patients with hematologic malignancies receiving cancer-directed therapy due to massive cellular breakdown. Spontaneous TLS is rare and occurs in the absence of cancer-directed therapy. Herein, we present a case of spontaneous TLS associated with squamous cell carcinoma.PMID:33456173 | PMC:PMC7785206 | DOI:10.1080/08998280.2020.1818911
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Mohammad Ammad Ud Din Syed Ather Hussain Leela Krishna Teja Boppana Dharmini Manogna Farhan Imran Source Type: research

Dermatomyositis, pembrolizumab, and squamous cell carcinoma of the lung
Proc (Bayl Univ Med Cent). 2020 Aug 27;34(1):120-121. doi: 10.1080/08998280.2020.1811189.ABSTRACTCancer immunotherapy has impacted the treatment of numerous tumor types, including skin, lung, and colon cancers. Immune checkpoint inhibitors (ICI) activate the immune system to attack cancer cells, but this mechanism can also impact healthy cells. Dermatomyositis, an autoimmune syndrome affecting multiple organ systems, is often associated with cancer as a paraneoplastic syndrome, but this syndrome can also be induced by ICI. Here, we describe a case of dermatomyositis in a patient receiving pembrolizumab for treatment of squ...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Claire J Wiggins Susan Y Chon Source Type: research

Hiatal hernia repair and magnetic sphincter augmentation to treat laryngopharyngeal reflux aiding the prevention of recurrent laryngeal cancer
We present a patient with a squamous cell cancer of the larynx who was diagnosed with gastroesophageal reflux disease (GERD) and found to have LPR. The cancer was treated locally and GERD was eradicated with magnetic sphincter augmentation. After 15 months of follow-up, there was no residual cancer. This case highlights the role that untreated LPR may play in patients' risk of developing laryngeal cancer.PMID:33456181 | PMC:PMC7785177 | DOI:10.1080/08998280.2020.1818167
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Madeline Smoot Marc A Ward Lindsey Arviso Christine E Sanchez Steven G Leeds Source Type: research

A perianal subcutaneous metastasis as the presenting sign for lung cancer
We report a case of a 77-year-old white man who presented with a 9-day history of a painful, rapidly growing mass on his left buttock in the gluteal cleft. The deep dermal location of the neoplasm and the lack of epidermal involvement led to suspicion of a metastatic carcinoma. Imaging showed a lung lesion suspected to be a primary malignancy with distant liver and gastric fundus metastases. Lung pathology showed primarily adenocarcinoma with squamous differentiation, whereas the skin biopsy showed poorly differentiated squamous cell carcinoma. Clinically, we concluded the skin carcinoma was a metastasis of a primary lung ...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Aaminah Azhar Elizabeth Wilder Source Type: research

Spontaneous tumor lysis syndrome in squamous cell carcinoma of the lung
Proc (Bayl Univ Med Cent). 2020 Sep 28;34(1):128-130. doi: 10.1080/08998280.2020.1818911.ABSTRACTTumor lysis syndrome (TLS) is an oncologic emergency, more commonly occurring in patients with hematologic malignancies receiving cancer-directed therapy due to massive cellular breakdown. Spontaneous TLS is rare and occurs in the absence of cancer-directed therapy. Herein, we present a case of spontaneous TLS associated with squamous cell carcinoma.PMID:33456173 | PMC:PMC7785206 | DOI:10.1080/08998280.2020.1818911
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Mohammad Ammad Ud Din Syed Ather Hussain Leela Krishna Teja Boppana Dharmini Manogna Farhan Imran Source Type: research

Dermatomyositis, pembrolizumab, and squamous cell carcinoma of the lung
Proc (Bayl Univ Med Cent). 2020 Aug 27;34(1):120-121. doi: 10.1080/08998280.2020.1811189.ABSTRACTCancer immunotherapy has impacted the treatment of numerous tumor types, including skin, lung, and colon cancers. Immune checkpoint inhibitors (ICI) activate the immune system to attack cancer cells, but this mechanism can also impact healthy cells. Dermatomyositis, an autoimmune syndrome affecting multiple organ systems, is often associated with cancer as a paraneoplastic syndrome, but this syndrome can also be induced by ICI. Here, we describe a case of dermatomyositis in a patient receiving pembrolizumab for treatment of squ...
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Claire J Wiggins Susan Y Chon Source Type: research

Hiatal hernia repair and magnetic sphincter augmentation to treat laryngopharyngeal reflux aiding the prevention of recurrent laryngeal cancer
We present a patient with a squamous cell cancer of the larynx who was diagnosed with gastroesophageal reflux disease (GERD) and found to have LPR. The cancer was treated locally and GERD was eradicated with magnetic sphincter augmentation. After 15 months of follow-up, there was no residual cancer. This case highlights the role that untreated LPR may play in patients' risk of developing laryngeal cancer.PMID:33456181 | PMC:PMC7785177 | DOI:10.1080/08998280.2020.1818167
Source: Baylor University Medical Center Proceedings - January 18, 2021 Category: Universities & Medical Training Authors: Madeline Smoot Marc A Ward Lindsey Arviso Christine E Sanchez Steven G Leeds Source Type: research