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Asthma Tied to Increased Risk for Multiple Cancers Asthma Tied to Increased Risk for Multiple Cancers
Asthma appears to increase the risk for melanoma as well as lung, blood, kidney, and ovarian cancers, but treatment with an inhaled steroid might reduce that risk.Medscape Medical News
Source: Medscape Allergy Headlines - May 6, 2023 Category: Allergy & Immunology Tags: Hematology-Oncology News Source Type: news

Low immunoglobulin-E levels as potential biomarker to screen individuals susceptible to cancer in occupational settings
Ferastraoaru et al1 reported an interesting observational study showing an enhanced risk of hematologic malignancies associated with low serum immunoglobulin (Ig)-E levels compared to subjects with non –low IgE levels in a cohort of emergency responders to the terrorist attack on the World Trade Centre (WTC). Most firefighters were of White ethnicity in their 40s, and risk estimates were adjusted for race (White vs non-White), age at blood draw smoking status, and time on arrival at the WTC. The study population was already known to be at risk of cancer in the 7 years after WTC disaster, especially prostate cancer, thyro...
Source: Annals of Allergy, Asthma and Immunology - December 1, 2022 Category: Allergy & Immunology Authors: Luca Cegolon, Francesca Larese Filon, Allan Prochazka, John H. Lange Tags: Editorial Source Type: research

Molecular Characteristics of Bladder Tumor: Increased Gene Expression of MAGE-A6 and MAGE-A11 with Decreased MicroRNA-34a and MicroRNA-125b
Iran J Allergy Asthma Immunol. 2022 Oct 26;21(5):561-573. doi: 10.18502/ijaai.v21i5.11043.ABSTRACTBladder cancer is recognized as one of the top ten most common cancers worldwide. Activation of oncogenes, inactivation of tumor suppressor genes, and dysregulation of androgen signaling pathways are three major pathophysiological causes in the development of bladder tumors. Discovering potential biomarkers is required for the management and immunotherapy of bladder cancer. Melanoma-associated antigen (MAGE)-A6 and MAGE-A11 are two cancer-testis antigens that are potential coregulators of androgen receptors. MicroRNAs, especia...
Source: Iranian Journal of Allergy, Asthma and Immunology - November 7, 2022 Category: Allergy & Immunology Authors: Azin Aghamajidi Zahra Ousati Ashtiani Monireh Mohsenzadegan Nader Tajik Mahmood Ghafoori Yazdi Laleh Sharifi Mohammad Reza Nowroozi Source Type: research

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