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Antihepatoma peptide, scolopentide, derived from the centipede scolopendra subspinipes mutilans
CONCLUSION: Scolopentide, an antihepatoma peptide purified from centipedes, may inspire new antihepatoma agents. Scolopentide activates DR4 and DR5 and induces apoptosis in liver cancer cells through a mitochondria-independent pathway.PMID:37032730 | PMC:PMC10080696 | DOI:10.3748/wjg.v29.i12.1875
Source: World Journal of Gastroenterology : WJG - April 10, 2023 Category: Gastroenterology Authors: Yu-Xing Hu Zhuo Liu Zhen Zhang Zhe Deng Zhen Huang Ting Feng Qing-Hong Zhou Si Mei Chun Yi Qing Zhou Pu-Hua Zeng Gang Pei Sha Tian Xue-Fei Tian Source Type: research

Strategies to overcome resistance to ALK inhibitors in non-small cell lung cancer: a narrative review
CONCLUSIONS: Strategies to overcome resistance to currently available ALK inhibitors are urgently needed. Given the variety of resistance mechanisms, tailormade approaches are required for disease control.PMID:37057106 | PMC:PMC10087990 | DOI:10.21037/tlcr-22-708
Source: Cell Research - April 14, 2023 Category: Cytology Authors: Aakash Desai Christine M Lovly Source Type: research

Antihepatoma peptide, scolopentide, derived from the centipede scolopendra subspinipes mutilans
CONCLUSION: Scolopentide, an antihepatoma peptide purified from centipedes, may inspire new antihepatoma agents. Scolopentide activates DR4 and DR5 and induces apoptosis in liver cancer cells through a mitochondria-independent pathway.PMID:37032730 | PMC:PMC10080696 | DOI:10.3748/wjg.v29.i12.1875
Source: World Journal of Gastroenterology : WJG - April 10, 2023 Category: Gastroenterology Authors: Yu-Xing Hu Zhuo Liu Zhen Zhang Zhe Deng Zhen Huang Ting Feng Qing-Hong Zhou Si Mei Chun Yi Qing Zhou Pu-Hua Zeng Gang Pei Sha Tian Xue-Fei Tian Source Type: research