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Cancer: Lymphoma
Drug: Fortamet
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Total 68 results found since Jan 2013.
Crizotinib induces pulmonary toxicity by blocking autophagy flux in alveolar epithelial cells
In conclusion, our study revealed the mechanism of crizotinib-induced apoptosis of alveolar epithelial cells and activation of inflammation during the onset of pulmonary toxicity and provided a promising therapeutic strategy for the treatment of crizotinib-induced pulmonary toxicity.PMID:37290598 | DOI:10.1016/j.bcp.2023.115636
Source: Biochemical Pharmacology - June 8, 2023 Category: Drugs & Pharmacology Authors: Yuanteng Zhang Zizheng Gao Zezheng Pan Huangxi Fu Feng Jiang Hao Yan Bo Yang Qiaojun He Peihua Luo Zhifei Xu Xiaochun Yang Source Type: research
Reduced Progression of Monoclonal Gammopathy of Undetermined Significance to Multiple Myeloma in Type 2 Diabetes Mellitus: Will Metformin Never Stop Its Pleasant Surprises?
Adv Ther. 2022 Mar 28. doi: 10.1007/s12325-022-02125-1. Online ahead of print.ABSTRACTMonoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic plasma cell disorder characterised by a serum M protein level below 3 g/dL, percentage of bone marrow clonal plasma cells below 10%, absence of end-organ damage (hypercalcaemia, renal insufficiency, anaemia, bone lesions) and absence of any other disease known to produce M protein. MGUS may progress to myeloproliferative disorders or multiple myeloma, but very little is known about any modifiable risk factors or any preventative treatment that might delay this pr...
Source: Adv Data - March 28, 2022 Category: Epidemiology Authors: Stella Papachristou Djordje S Popovic Nikolaos Papanas Source Type: research
Morphoproteomics Identifies SIRT1, EZH2 and CXCR4 Pathways in Diffuse Large B-Cell Lymphoma: Therapeutic Implications
CONCLUSION: By targeting the Sirt1, EZH2 and CXCR4 pathways using relatively non-toxic adjuvant therapeutic agents such as metformin, melatonin, curcumin, sulforaphane, vitamin D3 and plerixafor, we should be able to target the biology of DLBCL.PMID:35181615
Source: Annals of Clinical and Laboratory Science - February 19, 2022 Category: Laboratory Medicine Authors: Robert E Brown Songlin Zhang Xiaohong I Wang Source Type: research
