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Long ‐Term Safety of Growth Hormone – A Combined Registry Analysis
ConclusionsPatients with risk factors for malignancy or type 2 diabetes should be treated with caution and monitored during follow‐up, but current published data provide reassurance on the long‐term safety profile of GH in patients receiving GH treatment.This article is protected by copyright. All rights reserved.
Source: Clinical Endocrinology - October 21, 2017 Category: Endocrinology Authors: Kirstine Stochholm, Wieland Kiess Tags: Unsolicited Review Source Type: research

Long ‐term safety of growth hormone—A combined registry analysis
ConclusionsPatients with risk factors for malignancy or type 2 diabetes should be treated with caution and monitored during follow‐up, but current published data provide reassurance on the long‐term safety profile of GH in patients receiving GH treatment.
Source: Clinical Endocrinology - November 20, 2017 Category: Endocrinology Authors: Kirstine Stochholm, Wieland Kiess Tags: UNSOLICITED REVIEW Source Type: research

Cardiovascular Programming During and After Diabetic Pregnancy: Role of Placental Dysfunction and IUGR
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - April 8, 2019 Category: Endocrinology Source Type: research

Identification of Novel Biomarkers for Pre-diabetic Diagnosis Using a Combinational Approach
Reliable protein markers for pre-diabetes in humans are not clinically available. In order to identify novel and reliable protein markers for pre-diabetes in humans, healthy volunteers and patients diagnosed with pre-diabetes and stroke were recruited for blood collection. Blood samples were collected from healthy and pre-diabetic subjects 12 h after fasting. BMI was calculated from body weight and height. Fasting blood glucose (FBG), glycated hemoglobin (HbA1C), triglyceride (TG), total cholesterol, high-density lipoprotein, low-density lipoprotein (LDL), insulin and albumin were assayed by automated clinical laboratory ...
Source: Frontiers in Endocrinology - April 28, 2021 Category: Endocrinology Source Type: research