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New xanthones and cytotoxic constituents from Garcinia mangostana fruit hulls against human hepatocellular, breast, and colorectal cancer cell lines
Conclusion Fourteen compounds were isolated from chloroform fraction of G. mangostana fruit hulls. Cytotoxic properties exhibited by the isolated xanthones from G. mangostana reinforce the avail of it as a natural cytotoxic agent against various cancers. These evidences could provide relevant bases for the scientific rationale of using G. mangostana in anti-cancer treatment. Graphical abstract
Source: Journal of Ethnopharmacology - January 25, 2017 Category: Drugs & Pharmacology Source Type: research

Pharmaceutical Approval Update.
Authors: Gohil K Abstract Deoxycholic acid (Kybella) for submental fat; codeine polistirex/chlorpheniramine polistirex extended-release (Tuzistra XR) for coughs, allergies, and colds; ramucirumab (Cyramza) for colorectal cancer; and fluticasone furoate/vilanterol (Breo Ellipta) for asthma. PMID: 26185402 [PubMed]
Source: P and T - December 12, 2015 Category: Drugs & Pharmacology Tags: P T Source Type: research