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Prescription patterns of analgesics in cancer patients with bone metastases in Japan: a retrospective database study
CONCLUSION: In Japanese cancer patients with bone metastases, acetaminophen, NSAIDs, and weak or strong opioids were commonly used; their use increased after SREs developed. Opioid use increased closer to death.PMID:37314600 | DOI:10.1007/s10147-023-02365-3
Source: Clinical Breast Cancer - June 14, 2023 Category: Cancer & Oncology Authors: Shingo Sato Hideyuki Tomitori Atsushi Okawa Kyoko Akano Source Type: research

Multinational Study of the Efficacy and Safety of Humanized Anti-HER2 Monoclonal Antibody in Women Who Have HER2-Overexpressing Metastatic Breast Cancer That Has Progressed After Chemotherapy for Metastatic Disease
CONCLUSION: Recombinant humanized anti-HER2 monoclonal antibody, administered as a single agent, produces durable objective responses and is well tolerated by women with HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. Side effects that are commonly observed with chemotherapy, such as alopecia, mucositis, and neutropenia, are rarely seen.PMID:36881998 | DOI:10.1200/JCO.22.02510
Source: Clinical Breast Cancer - March 7, 2023 Category: Cancer & Oncology Authors: Melody A Cobleigh Charles L Vogel Debu Tripathy Nicholas J Robert Susy Scholl Louis Fehrenbacher Janet M Wolter Virginia Paton Steven Shak Gracie Lieberman Dennis J Slamon Source Type: research

Effect of COX-2 inhibitors and other non-steroidal inflammatory drugs on breast cancer risk: a meta-analysis
Abstract Evidence on non-steroidal anti-inflammatory drugs (NSAID) use and breast cancer risk shows a slightly protective effect of these drugs, but previous studies lack randomized clinical trial results and present high heterogeneity in exposure measurement. This systematic review and meta-analysis widens the knowledge about NSAID use and breast cancer risk, updating the information from the last meta-analysis, focusing on evidence on specific effects of COX-2 inhibitors and differential expression patterns of hormonal receptors. A PubMed-database search was conducted to include all entries published with the ke...
Source: Breast Cancer Research and Treatment - January 15, 2015 Category: Cancer & Oncology Source Type: research