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Stroke after Radiotherapy for Head and Neck Cancer – What is the Risk?
Treating head and neck squamous cell carcinomas with radiotherapy has been shown to cause damage to the cerebrovasculature. This retrospective cohort study found that any exposure to radiation was associated with a 46% higher hazard of stroke, and with radiotherapy as the sole treatment modality, 70% increased risk of stroke compared to surgery alone. Implications of this research speak to the need for adequate follow-up and survivorship care among patients that were treated with RT.
Source: International Journal of Radiation Oncology * Biology * Physics - July 15, 2016 Category: Radiology Authors: Erin Arthurs, Timothy P. Hanna, Khaled Zaza, Yingwei Peng, Stephen F. Hall Source Type: research

Stroke After Radiation Therapy for Head and Neck Cancer: What Is the Risk?
A retrospective population-based cohort study was conducted to determine the risk of ischemic stroke with respect to time, associated with curative radiation therapy in head and neck squamous cell carcinomas (HNSCC).
Source: International Journal of Radiation Oncology * Biology * Physics - July 15, 2016 Category: Radiology Authors: Erin Arthurs, Timothy P. Hanna, Khaled Zaza, Yingwei Peng, Stephen F. Hall Tags: Clinical Investigation Source Type: research

A nomogram for the prediction of cerebrovascular disease among patients with brain necrosis after radiotherapy for nasopharyngeal carcinoma
In various cancer populations, radiotherapy is associated with the development of vascular disease [1 –4]. Previous studies have established an increased incidence of carotid stenosis (CAS) and ischemic stroke in patients with head and neck cancer treated with radiotherapy [4,5]. A study of 6862 patients (age>65  years) showed that five-year incidence of cerebrovascular events was 19% in patients treated with radiotherapy alone compared with 14% in patients treated with surgery plus radiotherapy; the corresponding ten-year incidence were 34% and 25%, respectively [4].
Source: Radiotherapy and Oncology - December 21, 2018 Category: Radiology Authors: Jinhua Cai, Jinping Cheng, Honghong Li, Wei-Jye Lin, Yi Li, Xiaohuang Zhuo, Xiaolong Huang, Charles B. Simone, Wilbert S. Aronow, Edward L.W. Chow, Yamei Tang Tags: Original Article Source Type: research

PH-0384 Risk of stroke in nasopharyngeal cancer survivors: a national registry-based,population cohort study
Source: Radiotherapy and Oncology - August 1, 2021 Category: Radiology Authors: T.H. Tan Tags: Poster highlights: Poster highlights 14: Head and neck 2 Source Type: research

A novel nomogram to predict overall survival in head and neck cancer survivors with radiation-induced brain necrosis
CONCLUSION: In this LASSO-Cox model-based nomogram study, we developed and validated an easily applied model to predict overall survival in head and neck cancer survivors following an RN diagnosis.PMID:35121029 | DOI:10.1016/j.radonc.2022.01.033
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - February 5, 2022 Category: Radiology Authors: Dong Pan Xiaoming Rong Yingying Zhu Wai Tong Ng Dongping Chen Honghong Li Yongteng Xu Yamei Tang Radiation Oncology Palliative Care Collaborative Group Source Type: research