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Cancer: Gastrointestinal Stromal Tumor (GIST)
Management: National Institutes of Health (NIH)

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Total 18 results found since Jan 2013.

Prognostic Nomogram for Gastrointestinal Stromal Tumors after Surgery Based on the SEER Database
Biomed Res Int. 2022 Nov 14;2022:5639174. doi: 10.1155/2022/5639174. eCollection 2022.ABSTRACTWe aimed to determine prognostic factors and develop an effective and practical nomogram for predicting cancer-specific survival in gastrointestinal stromal tumor (GIST) patients. Postoperative data were obtained from the SEER database (2000-2018). Patients were divided into training and validation cohorts at random (7 : 3). Prognostic factors were screened, and a prognostic nomogram was established using log-rank testing and Cox regression. We used DCA, ROC curves, C-index, and calibration curves to evaluate our model's predictiv...
Source: Biomed Res - November 24, 2022 Category: Research Authors: Qianhui Sun Yunru Chen Tingting Li Xiaoyu Zhu Guanghui Zhu Baoyi Ni Ruike Gao Jie Li Source Type: research

Prognostic significance of MCM6 expression in gastrointestinal stromal tumor
Int J Clin Exp Pathol. 2021 Dec 15;14(12):1119-1127. eCollection 2021.ABSTRACTMinichromosome maintenance (MCM) proteins are essential for the initiation of DNA replication and they are prognostic markers in various human cancers. The aim of this study was to investigate the role of the MCM6 protein in gastrointestinal stromal tumor (GIST) and its clinical and prognostic significance. We evaluated MCM6 expression in 211 GIST samples using immunohistochemistry. We used the receiver operating characteristic curve (ROC) to identify optimal cut-off values. High MCM6 expression was associated with tumor size, mitosis, tumor necr...
Source: International Journal of Clinical and Experimental Pathology - January 14, 2022 Category: Pathology Authors: Young-Ran Shim Aeri Kim Mi-Jin Gu Source Type: research