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A Systematic Review on Predisposition to Lymphoid (B and T cell) Neoplasias in Patients With Primary Immunodeficiencies and Immune Dysregulatory Disorders (Inborn Errors of Immunity)
Conclusions Though this is not a comprehensive summary of malignancies in PIDDs, or even lymphoproliferative disease in this area, this review summarizes the Medline-indexed published reports of B and T lymphomas in patients with PIDDs. This report highlights the diversity of malignant lymphoproliferative disorders in setting of PIDDs, and its associated challenges of diagnosis and treatment. The pathological classification and nomenclature for the lymphoid malignancies with variably reported and postulated underlying mechanisms were inconsistent and inadequate for many of these published reports. A wide range of treatmen...
Source: Frontiers in Immunology - April 15, 2019 Category: Allergy & Immunology Source Type: research

Coronary and peripheral artery aneurysms in a patient with cutaneous T-cell lymphoma
A 48-year-old man was referred to our institution for acute limb ischaemia. He had been diagnosed with cutaneous T-cell lymphoma, so-called mycosis fungoides by gene rearrangement analysis of skin biopsy samples 9 years ago. He had received prednisolone 5 mg daily and phototherapy for mycosis fungoides. Although allergy symptoms and signs including asthma, peripheral neuropathy and glomerulonephritis had not been evident, his rashes had been worsening in his face and abdomen for a few months. On examination, enhanced CT revealed thrombotic occlusion in the left posterior tibial artery (figure 1A, B) and multiple ...
Source: Heart Asia - January 4, 2017 Category: Cardiology Authors: Yasutake, H., Ikeda, Y., Kawarada, O. Tags: Open access Images in cardiovascular medicine Source Type: research