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Cancer: Liver Cancer
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Total 137 results found since Jan 2013.

Prognostic value of S100A4 and Glypican-3 in hepatocellular carcinoma in cirrhotic HCV patients
CONCLUSION: S100A4 might be used as a prognostic marker for HCC, while GPC3 is a reliable marker of HCC diagnosis.PMID:37599312 | DOI:10.1186/s43046-023-00184-1
Source: J Egypt Natl Canc In... - August 20, 2023 Category: Cancer & Oncology Authors: Mahmoud El-Bendary Khaled Farid Mohammad Arafa Wagdi Elkashef Talaat Abdullah Ahmed El-Mesery Source Type: research

Interferon-induced transmembrane protein 3 in hepatocellular carcinoma patients
CONCLUSION: IFITM3 play an important role in progression of hepatocellular carcinoma. Results revealed that IFITM3 rs 12252-CC among Hepatocellular carcinoma patients would allow diagnosis and starting intervention.PMID:37353775 | DOI:10.1186/s12885-023-11071-2
Source: Cancer Control - June 23, 2023 Category: Cancer & Oncology Authors: Rania M Bondok Lamiaa A Barakat Alyaa R Elsergany Nancy Mahsoub Maivel H Ghattas Source Type: research

Biochemical, molecular and anti-tumor characterization of L-methionine gamma lyase produced by local < em > Pseudomonas < /em > sp. in Egypt
Saudi J Biol Sci. 2023 Jul;30(7):103682. doi: 10.1016/j.sjbs.2023.103682. Epub 2023 May 12.ABSTRACTA soil inhabiting Pseudomonas sp. has been examined for producing L- methionine gamma-lyase enzyme. The identity of the tested bacteria was verified by VITEK2, and MALDI-TOF analysis in addition to molecular confirmation by 16S rDNA sequence and submitted in Genbank under accession number ON993898.1. Production of the targeted enzyme was done using a commercial medium including L-methionine, as the main substrate. This obtained enzyme was precipitated using acetone (1:1v/v) followed by purification with Sephadex G100 and seph...
Source: Mol Biol Cell - June 12, 2023 Category: Molecular Biology Authors: Azza A Abou Zeid Asmaa H Mohamed Ashraf S A El-Sayed Ashraf M El-Shawadfy Source Type: research

miRNome of Child A hepatocellular carcinoma in Egyptian patients
DISCUSSION: In this research, 16 HCC and 6 tumor adjacent tissues (control) of Child A Egyptian patients were successfully profiled for the expression profile of miRNAs by NGS. Forty-one differentially expressed miRNAs (DEMs) were found by differential expression analysis, with 31 being upregulated and 10 being downregulated. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis was then conducted on these differentially expressed miRNAs revealing that Sensitivity and specificity analysis showed that hsa-miR-4488, hsa-miR-3178, and hsa-miR-3182 were unique miRNAs as they are expressed in HCC tissues on...
Source: Cancer Control - May 11, 2023 Category: Cancer & Oncology Authors: Hend E El-Shqnqery Rania Hassan Mohamed Omar Samir Islam Ayoub Wael M El-Sayed Ahmed A Sayed Source Type: research

Noninvasive identification of molecular biomarkers of hepatocellular carcinoma in HCV-Egyptian patients
CONCLUSIONS: Overall, our results indicate that CK-1 mRNA expression could help as a noninvasive tumor biomarker for HCC prognosis and diagnosis when combining with AFP.PMID:37121922 | DOI:10.1186/s43046-023-00170-7
Source: J Egypt Natl Canc In... - April 30, 2023 Category: Cancer & Oncology Authors: Ahmed Daif Mahmood A Al-Azzawi Moustafa A Sakr Hisham A Ismail Mahmoud Gadallah Source Type: research