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Cancer: Carcinoma
Therapy: Statin Therapy
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Total 144 results found since Jan 2013.
Evaluation of statin use and renal cell carcinoma risk identifies sex-specific associations with RCC subtypes
Conclusions: Statin use was not associated with the overall risk of RCC. However, it was associated with an increased risk of high-grade disease among women in the NHS cohort and an increased risk of clear cell RCC among men. The reasons for these inconsistent results by sex are unclear.PMID:37482537 | DOI:10.1080/0284186X.2023.2238883
Source: Acta Oncologica - July 23, 2023 Category: Cancer & Oncology Authors: Irmina Maria Michalek Rebecca E Graff Alejandro Sanchez Toni K Choueiri Eunyoung Cho Mark A Preston Kathryn M Wilson Source Type: research
Some pleiotropic effects of statins on hepatocellular carcinoma cells: Comparative study on atorvastatin, rosuvastatin and simvastatin
CONCLUSION: The less pronounced pleiotropic effects of rosuvastatin on HepG2 cells are probably due to differences in structure and solubility compared to atorvastatin and simvastatin. Transporter-dependent and a slower influx of rosuvastatin into cells compared to the tested lipophilic statins probably lead to a weaker accumulation of rosuvastatin in HepG2 cells, which results in less pronounced pleiotropic effects compared to lipophilic atorvastatin and simvastatin.PMID:37478516 | DOI:10.1016/j.advms.2023.07.002
Source: Advances in Medical Sciences - July 21, 2023 Category: Biomedical Science Authors: Esmeralda Dautovi ć Monika Rustemovi ć-Čorbić Nahida Srabovi ć Adaleta Softi ć Aida Smajlovi ć Maida Šljivić Husejnović Alen Hatki ć Dalila Halil čević Source Type: research
