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Specialty: Cardiology
Cancer: Cancer
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Total 468 results found since Jan 2013.
A Comparative Study of Ultrasmall Calcium Carbonate Nanoparticles for Targeting and Imaging Atherosclerotic Plaque
ACS Nano. 2023 Jul 3. doi: 10.1021/acsnano.3c03523. Online ahead of print.ABSTRACTAtherosclerosis is a complex disease that can lead to life-threatening events, such as myocardial infarction and ischemic stroke. Despite the severity of this disease, diagnosing plaque vulnerability remains challenging due to the lack of effective diagnostic tools. Conventional diagnostic protocols lack specificity and fail to predict the type of atherosclerotic lesion and the risk of plaque rupture. To address this issue, technologies are emerging, such as noninvasive medical imaging of atherosclerotic plaque with customized nanotechnologic...
Source: Atherosclerosis - July 3, 2023 Category: Cardiology Authors: Lydia Mart ínez-Parra Marina Pi ñol-Cancer Carlos Sanchez-Cano Ana B Miguel-Coello Desir è Di Silvio Ana M Gomez Clara Uriel Sandra Plaza-Garc ía Marta Gallego Raquel Pazos Hugo Groult Marc Jeannin Kalotina Geraki Laura Fern ández-Méndez Ainhize Urk Source Type: research
Occam ’s Razor Versus Hickam’s Dictum in a Presentation of STEMI
A 79-year-old female presented with an inferolateral STEMI on a background of a recent multi-territorial stroke, hypertension, hypercholesterolaemia, and prior thyroidectomy for thyroid cancer. Percutaneous intervention involved a drug-eluting balloon to the culprit oblique marginal artery and medically managed calcified 80% ostial right coronary artery (RCA). New paroxysmal atrial fibrillation (AF) was noted. Transthoracic echocardiogram revealed a 13x7 mm mobile aortic valve mass with mild regurgitation.
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: T. Tran, V. Dang, K. Cho, J. Cham, T. Nguyen Source Type: research
Red Meat Consumption and its Relationship With Cardiovascular Health: A Review of Pathophysiology and Literature
Cardiol Rev. 2023 Jun 26. doi: 10.1097/CRD.0000000000000575. Online ahead of print.ABSTRACTRed meat is the muscle meat of mammals like beef, lamb, and pork that is red due to the abundance of myoglobin pigment and becomes even darker when cooked. The global average per capita consumption of meat and the total amount of meat consumed is rising, and there has been a particularly marked increase in the global consumption of chicken and pork. The consumption of red meat has always been a contentious issue, with data suggesting benefits in terms of nutritional value and at the same time linking its consumption to major health d...
Source: Atherosclerosis - June 26, 2023 Category: Cardiology Authors: Bhupinder Singh Abdul Allam Khan Fnu Anamika Ripudaman Munjal Jaskaran Munjal Rohit Jain Source Type: research
Insulin Regulation of Hepatic Lipid Homeostasis
Compr Physiol. 2023 Jun 26;13(3):4785-4809. doi: 10.1002/cphy.c220015.ABSTRACTThe incidence of obesity, insulin resistance, and type II diabetes (T2DM) continues to rise worldwide. The liver is a central insulin-responsive metabolic organ that governs whole-body metabolic homeostasis. Therefore, defining the mechanisms underlying insulin action in the liver is essential to our understanding of the pathogenesis of insulin resistance. During periods of fasting, the liver catabolizes fatty acids and stored glycogen to meet the metabolic demands of the body. In postprandial conditions, insulin signals to the liver to store exc...
Source: Atherosclerosis - June 26, 2023 Category: Cardiology Authors: Kahealani Uehara Dominic Santoleri Anna E Garcia Whitlock Paul M Titchenell Source Type: research
Association of cervical atherosclerosis on Doppler ultrasonography and postoperative delirium in patients undergoing spinal surgery: a single-center, retrospective, observational study
CONCLUSIONS: There was a significant association between POD and the prevalence of cervical atherosclerosis using the univariate logistic regression analysis. Furthermore, multivariate logistic regression analyses showed that older age and antiplatelet agent use were independently associated with POD.PMID:37326838 | DOI:10.1007/s00586-023-07823-0
Source: Atherosclerosis - June 16, 2023 Category: Cardiology Authors: Gentaro Kumagai Kanichiro Wada Toru Asari Yohshiro Nitobe Hirotaka Kinoshita Tetsuya Kushikata Kazuyoshi Hirota Yasuyuki Ishibashi Source Type: research
Incident cardiovascular events and imaging phenotypes in UK Biobank participants with past cancer
Conclusions
Cancer history is linked to increased risk of incident CVDs and adverse cardiac remodelling independent of shared vascular risk factors.
Source: Heart - June 14, 2023 Category: Cardiology Authors: Raisi-Estabragh, Z., Cooper, J., McCracken, C., Crosbie, E. J., Walter, F. M., Manisty, C. H., Robson, J., Mamas, M. A., Harvey, N. C., Neubauer, S., Petersen, S. E. Tags: Open access, Editor's choice, Press releases Cardiac risk factors and prevention Source Type: research
Atherosclerosis-related biomarker PABPC1 predicts pan-cancer events
CONCLUSIONS: Through the findings of SEREX and bioinformatics pan-cancer analysis, we concluded that PABPC1 might serve as a potential biomarker for the prediction and diagnosis of AS and pan-cancer.PMID:37311641 | DOI:10.1136/svn-2022-002246
Source: Atherosclerosis - June 13, 2023 Category: Cardiology Authors: Miao Lin Liubing Hu Si Shen Jiyue Liu Yanyan Liu Yixian Xu Honglin Chen Kazuo Sugimoto Jianshuang Li Ikuo Kamitsukasa Takaki Hiwasa Hao Wang Anding Xu Source Type: research
Genomics of aging: Reactive oxidation and inefficient mitochondria
This article, the fifth in the JAANP Genomics of Aging series, describes the role that mitochondrial dysfunction plays in the development of age-related diseases such as Alzheimer disease, Parkinson disease, cancer, heart disease, and stroke.PMID:37265351 | DOI:10.1097/JXX.0000000000000880
Source: Atherosclerosis - June 2, 2023 Category: Cardiology Authors: Kenneth Wysocki Beth Heuer Source Type: research
Neuroprotective effect of aloe emodin against Huntington's disease-like symptoms in R6/1 transgenic mice
Food Funct. 2023 May 16. doi: 10.1039/d3fo00156c. Online ahead of print.ABSTRACTAloe emodin is a natural anthraquinone derived from aloe or rhubarb, showing anti-renal fibrosis, anti-atherosclerosis and anti-cancer effects. Aloe emodin also shows neuroprotective effects in ischemic stroke rats. Naturally, anthraquinone derivatives generally have the effect of inhibiting the transforming growth factor-β1 (TGF-β1) pathway. There is an increase in the calcium/calmodulin-dependent protein kinase II (CaMKII) and TGF-β1 levels in both Huntington's disease (HD) patients' brains and HD transgenic mice. Thus, we hypothesized tha...
Source: Atherosclerosis - May 16, 2023 Category: Cardiology Authors: Nan Yan Shuai Wang Haotian Gao Jiaqi Chen Jiahui Cao Pengsheng Wei Xue Li Ying Yu Yan Wang Yalin Niu Yijie Wang Shuyuan Liu Ge Jin Source Type: research
Understanding HAT1: A Comprehensive Review of Noncanonical Roles and Connection with Disease
Genes (Basel). 2023 Apr 14;14(4):915. doi: 10.3390/genes14040915.ABSTRACTHistone acetylation plays a vital role in organizing chromatin, regulating gene expression and controlling the cell cycle. The first histone acetyltransferase to be identified was histone acetyltransferase 1 (HAT1), but it remains one of the least understood acetyltransferases. HAT1 catalyzes the acetylation of newly synthesized H4 and, to a lesser extent, H2A in the cytoplasm. However, 20 min after assembly, histones lose acetylation marks. Moreover, new noncanonical functions have been described for HAT1, revealing its complexity and complicating th...
Source: Atherosclerosis - April 28, 2023 Category: Cardiology Authors: Miguel A Ortega Diego De Leon-Oliva Cielo Garcia-Montero Oscar Fraile-Martinez Diego Liviu Boaru Mar ía Del Val Toledo Lobo Ignacio Garc ía-Tuñón Mar Royuela Natalio Garc ía-Honduvilla Julia Bujan Luis G Guijarro Melchor Alvarez-Mon Miguel Ángel Alv Source Type: research
Correlation Between Chronic Periodontitis and Lung Cancer: A Systematic Review With Meta-Analysis
Cureus. 2023 Mar 21;15(3):e36476. doi: 10.7759/cureus.36476. eCollection 2023 Mar.ABSTRACTPeriodontal disease is associated with many systemic diseases, such as cardiovascular diseases, atherosclerosis, diabetes mellitus, stroke, and pulmonary diseases. Interestingly, recent literature suggests that periodontal disease might be a risk factor for various cancers such as lung, colon, oesophageal, head, and neck cancers. However, the precise mechanistic link is lacking. Hence, in this meta-analysis, we aimed to investigate the correlation between periodontal disease and lung cancer in periodontally diseased patients. Data wer...
Source: Atherosclerosis - April 24, 2023 Category: Cardiology Authors: Umesh P Verma Pooja Singh Ajay K Verma Source Type: research
