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Total 83 results found since Jan 2013.

Problem-patients in HRT
Since the Women's Health Initiative (WHI) has been stopped 2002 due to increased risk of venous thromboembolism, myocardial infarction, stroke and breast cancer, safety issues have got great concern using hormone replacement therapy (HRT). However, using lower dosages, other hormonal components and/or transdermal instead of oral application can reduce those risks although not demonstrated in a placebo-controlled study comparable to WHI. However, this has been shown in large case/control- and cohort-studies reflecting more practical conditions in contrast to WHI.
Source: Maturitas - May 14, 2019 Category: Primary Care Authors: Alfred O. Mueck Tags: INV65 Source Type: research

Comorbidity in patients with cardiovascular disease in primary care: a cohort study with routine healthcare data.
CONCLUSION: Comorbid conditions are very common in patients with CVD, even in younger age groups. To ensure efficient and effective treatment, organisational adaptations may be required in the healthcare system to accommodate comorbid conditions in patients with CVD. PMID: 31064742 [PubMed - as supplied by publisher]
Source: The British Journal of General Practice - May 6, 2019 Category: Primary Care Authors: Buddeke J, Bots ML, van Dis I, Visseren FL, Hollander M, Schellevis FG, Vaartjes I Tags: Br J Gen Pract Source Type: research

Stroke, Heart Attack Risk Increases in Months Before Cancer Dx
(MedPage Today) -- Fivefold increase seen in month before diagnosis in older adults
Source: MedPage Today Primary Care - December 21, 2018 Category: Primary Care Source Type: news

A Clinical Prescription for Heart Health in Midlife Women
Heart disease remains the leading cause of death in women in Europe and the United States with the incidence increasing during midlife. [1] While one in thirty-one women will die from breast cancer, one in approximately two to three women will die from heart disease or stroke. [1,2], While most women are aware about traditional cardiovascular disease (CVD) risk factors, such as hypertension, dyslipidemia and diabetes, they are often unaware of sex specific risk factors that occur in midlife. [3] Clinical risk factors can vary depending on the individual personal family history and can change as a woman ages.
Source: Maturitas - November 12, 2018 Category: Primary Care Authors: Chrisandra Shufelt, Erika Dutra, Tina Torbati, Tina Ramineni Source Type: research

Real-world retrospective cohort study ARCTIC shows burden of comorbidities in Swedish COPD versus non-COPD patients.
This study aimed to generate real-world evidence to assess the burden of comorbidities in COPD patients, to effectively manage these patients and optimize the associated healthcare resource allocation. ARCTIC is a large, real-world, retrospective cohort study conducted in Swedish COPD patients using electronic medical record data collected between 2000 and 2014. These patients were studied for prevalence of various comorbidities and for association of these comorbidities with exacerbations, mortality, and healthcare costs compared with an age-, sex-, and comorbidities-matched non-COPD reference population. A total of 17,47...
Source: Primary Care - September 10, 2018 Category: Primary Care Authors: Ställberg B, Janson C, Larsson K, Johansson G, Kostikas K, Gruenberger JB, Gutzwiller FS, Jorgensen L, Uhde M, Lisspers K Tags: NPJ Prim Care Respir Med Source Type: research

When hormonal treatment is not an option
An integrated analysis of safety data from seven Phase 2/3 double-blind, placebo-controlled trials has been conducted for ospemifene (Senshio ®). Adverse drug reactions are well characterized, benign and not unexpected from a SERM used for the treatment of VVA (i.e. hot flushes, leg cramps). There is no evidence to date that ospemifene leads to an increase in vaginal bleeding, endometrial hyperplasia or cancer; VTE, stroke or other cardi ovascular events; or any other adverse event of special interest.
Source: Maturitas - February 14, 2018 Category: Primary Care Authors: Felix Lugo Source Type: research

Post-Stroke Cancer Risk among Postmenopausal Women: The Women's Health Initiative
Associations between a history of cancer and higher subsequent stroke risk have been established. However, whether a history of stroke is associated with higher subsequent cancer risk, especially for cancers with overlapping risk factors for stroke, is unknown. Therefore, we examined whether a history of stroke was associated with subsequent cancer risk and tumor site, by race/ethnicity, among postmenopausal women.
Source: Womens Health Issues - November 30, 2017 Category: Primary Care Authors: Shawnita Sealy-Jefferson, Michele L. Cote, Rowan T. Chlebowski, Kathryn M. Rexrode, Michael S. Simon Tags: Original article Source Type: research

Aspirin for Primary Prevention
Aspirin reduces the risk of nonfatal myocardial infarction and stroke, and the risk of colorectal cancer. Aspirin increases the risk of gastrointestinal and intracranial bleeding. The best available evidence supports initiating aspirin in select populations. In 2016, the US Preventive Services Task Force recommended initiating aspirin for the primary prevention of both cardiovascular disease and colorectal cancer among adults ages 50 to 59 who are at increased risk for cardiovascular disease. Adults 60 to 69 who are at increased cardiovascular disease risk may also benefit. There remains considerable uncertainty about whet...
Source: Medical Clinics of North America - June 1, 2017 Category: Primary Care Authors: Ilana B. Richman, Douglas K. Owens Source Type: research

Factors Associated With Seeking Physician Care by Medicare Beneficiaries Who Receive All Their Primary Care From Nurse Practitioners.
CONCLUSIONS: About half of Medicare patients under exclusive NP primary care switched to physicians for some or all primary care over a 3-year period. Future study is needed to understand the reasons for switching. PMID: 27456894 [PubMed - as supplied by publisher]
Source: Primary Care - July 24, 2016 Category: Primary Care Authors: Raji MY, Chen NW, Raji M, Kuo YF Tags: J Prim Care Community Health Source Type: research

Self-reported impact of caregiving on voluntary home-based caregivers in Mutale Municipality, South Africa.
CONCLUSION: Voluntary home-based caregivers have an important role in the provision of palliative care to people in their own homes, and therefore, the negative caregiving impact on the lives of caregivers may compromise the provision of quality palliative care. PMID: 27380854 [PubMed - in process]
Source: Primary Care - July 7, 2016 Category: Primary Care Authors: Mashau NS, Netshandama VO, Mudau MJ Tags: Afr J Prim Health Care Fam Med Source Type: research

Are gender-specific approaches required to prevent dementia?
Whereas smart people enjoy many advantages including their longer and healthier lives, older men are not well-known for taking care of their health. Eubie Blake ’s humour reveals a lifetime of ignorance about his right or wrong health choices. He showed with wit that these may not become personally relevant until old age. Although older adults are sometimes more fearful of dementia than they are of cancer or stroke, few are aware of those life style choic es that could have lowered their personal dementia risk.
Source: Maturitas - June 30, 2016 Category: Primary Care Authors: Lawrence J. Whalley Tags: Editorial Source Type: research

French Intensive Care Society, International congress - Réanimation 2016.
C, Sauneuf B, Verrier P, Pottier V, Orabona M, Samba D, Viquesnel G, Lermuzeaux M, Hazera P, Hanouz JL, Parienti JJ, Du Cheyron D, Demoule A, Clavel M, Rolland-Debord C, Perbet S, Terzi N, Kouatchet A, Wallet F, Roze H, Vargas F, Guérin C, Dellamonica J, Jaber S, Similowski T, Quenot JP, Binquet C, Vinsonneau C, Barbar SD, Vinault S, Deckert V, Lemaire S, Hssain AA, Bruyère R, Souweine B, Lagrost L, Adrie C, Jung B, Daurat A, De Jong A, Chanques G, Mahul M, Monnin M, Molinari N, Lheureux O, Trepo E, Hites M, Cotton F, Wolff F, Surin R, Créteur J, Vincent JL, Gustot T, Jacobs F, Taccone FS, Neuville M, Timsit JF, El-Hel...
Source: Australian Family Physician - May 31, 2016 Category: Primary Care Authors: Jaillette E, Girault C, Brunin G, Zerimech F, Chiche A, Broucqsault-Dedrie C, Fayolle C, Minacori F, Alves I, Barrailler S, Robriquet L, Delaporte E, Thellier D, Delcourte C, Duhamel A, Nseir S, Valette X, Desmeulles I, Savary B, Masson R, Seguin A, Daubi Tags: Ann Intensive Care Source Type: research

Top 20 Research Studies of 2015 for Primary Care Physicians.
This article, the fifth installment in this annual series, summarizes the 20 POEMs based on original research studies judged to have the greatest clinical relevance for family physicians. Key recommendations include questioning the need for backup throat cultures; avoiding early imaging and not adding cyclobenzaprine or oxycodone to naproxen for patients with acute low back pain; and encouraging patients with chronic or recurrent low back pain to walk. Other studies showed that using a nicotine patch for more than eight weeks has little benefit; that exercise can prevent falls that cause injury in at-risk older women; and ...
Source: American Family Physician - April 30, 2016 Category: Primary Care Authors: Ebell MH, Grad R Tags: Am Fam Physician Source Type: research

Obesity Statistics.
Abstract Obesity is a chronic disease that is strongly associated with an increase in mortality and morbidity including, certain types of cancer, cardiovascular disease, disability, diabetes mellitus, hypertension, osteoarthritis, and stroke. In adults, overweight is defined as a body mass index (BMI) of 25 kg/m(2) to 29 kg/m(2) and obesity as a BMI of greater than 30 kg/m(2). If current trends continue, it is estimated that, by the year 2030, 38% of the world's adult population will be overweight and another 20% obese. Significant global health strategies must reduce the morbidity and mortality associated with...
Source: Primary Care - February 21, 2016 Category: Primary Care Authors: Smith KB, Smith MS Tags: Prim Care Source Type: research

Obesity Statistics
Obesity is a chronic disease that is strongly associated with an increase in mortality and morbidity including, certain types of cancer, cardiovascular disease, disability, diabetes mellitus, hypertension, osteoarthritis, and stroke. In adults, overweight is defined as a body mass index (BMI) of 25 kg/m2 to 29 kg/m2 and obesity as a BMI of greater than 30 kg/m2. If current trends continue, it is estimated that, by the year 2030, 38% of the world’s adult population will be overweight and another 20% obese. Significant global health strategies must reduce the morbidity and mortality associated with the obesity epidemic.
Source: Primary Care: Clinics in Office Practice - January 12, 2016 Category: Primary Care Authors: Kristy Breuhl Smith, Michael Seth Smith Source Type: research