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Specialty: Neurology
Cancer: Cancer

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Total 386 results found since Jan 2013.

Cancer-associated stroke: a study of prevalence and predictors among ischaemic stroke patients
CONCLUSIONS: A high prevalence of systemic cancer, of any type, as well as active and occult, was found among patients with ischaemic stroke. The presence of ischaemic lesions in several vascular territories and some laboratory markers could be factors to consider in attributing the stroke to cancer or looking for an occult neoplasm in some patients.PMID:36908032 | DOI:10.33588/rn.7606.2022414
Source: Revista de Neurologia - March 13, 2023 Category: Neurology Authors: Y Bravo-Anguiano A Echavarr ía-Iñiguez E Madrigal-Lkhou A Mu ñoz-Martín Source Type: research

PHLDA1 knockdown alleviates mitochondrial dysfunction and endoplasmic reticulum stress-induced neuronal apoptosis via activating PPAR γ in cerebral ischemia-reperfusion injury
Brain Res Bull. 2023 Jan 18:S0361-9230(23)00010-2. doi: 10.1016/j.brainresbull.2023.01.007. Online ahead of print.ABSTRACTMitochondrial dysfunction and endoplasmic reticulum (ER) stress occur in ischemic stroke. The disruption of these two organelles can directly lead to cell death through various signaling pathways. Thus, investigation of the associated molecular mechanisms in cerebral ischemia is a prerequisite for stroke treatment. Pleckstrin homology-like domain family A member 1 (PHLDA1) is a multifunctional protein that can modulate mitochondrial function and ER stress in cardiomyocyte and cancer cells. This work stu...
Source: Brain Research Bulletin - January 21, 2023 Category: Neurology Authors: Yushuang Liu Hanshu Zhao Nan Chen Yuelong Li Zeyang Zheng Zhiyu Sun Zhongling Zhang Source Type: research