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Specialty: Cardiology
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Total 468 results found since Jan 2013.

Relationships between Age at Menarche and Risk of Cardiovascular Disease Mortality among Japanese Women: The Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC) Study
CONCLUSIONS: Both women with early and late age at menarche were determined to have higher risk of death from stroke and cardiovascular disease.PMID:35584930 | DOI:10.5551/jat.63321
Source: Journal of Atherosclerosis and Thrombosis - May 18, 2022 Category: Cardiology Authors: Kanako Ota Kazumasa Yamagishi Rie Kishida Tomomi Kihara Renzhe Cui Akiko Tamakoshi Hiroyasu Iso JACC Study group Source Type: research

Pyruvate Kinase M2: a novel regulator of adipogenesis
FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.L7944.ABSTRACTObesity is the cornerstone of many other conditions, with far-reaching impacts on numerous body systems and quality of life. Obesity is closely and likely causally associated with metabolic syndrome and consequent atherosclerosis, heart disease, stroke, and type 2 diabetes as well as diseases such as cancer and osteoarthritis. Recent studies suggest exploring the possibility of activating brown adipose tissue as a potential anti-obesity strategy. However, understanding the mechanisms underlying the processes of brown adipogenesis and browning is fou...
Source: Atherosclerosis - May 13, 2022 Category: Cardiology Authors: Presley D Dowker Jenna B Demeter Ahmed Bettaieb Source Type: research

Involvement of Ceramide Metabolism in Cerebral Ischemia
Front Mol Biosci. 2022 Apr 20;9:864618. doi: 10.3389/fmolb.2022.864618. eCollection 2022.ABSTRACTIschemic stroke, caused by the interruption of blood flow to the brain and subsequent neuronal death, represents one of the main causes of disability in worldwide. Although reperfusion therapies have shown efficacy in a limited number of patients with acute ischemic stroke, neuroprotective drugs and recovery strategies have been widely assessed, but none of them have been successful in clinical practice. Therefore, the search for new therapeutic approaches is still necessary. Sphingolipids consist of a family of lipidic molecul...
Source: Atherosclerosis - May 9, 2022 Category: Cardiology Authors: Alberto Ouro Clara Correa-Paz Elena Maqueda Ant ía Custodia Marta Aramburu-N úñez Daniel Romaus-Sanjurjo Adri án Posado-Fernández Mar ía Candamo-Lourido Maria Luz Alonso-Alonso Pablo Hervella Ram ón Iglesias-Rey Jos é Castillo Francisco Campos Tom Source Type: research

Risk factors of arterial thrombotic events after unprovoked venous thromboembolism, and after cancer associated venous thromboembolism: A prospective cohort study
CONCLUSIONS: The risk of ATE after unprovoked VTE and after cancer-associated VTE, is determined by some classic cardiovascular risk factors and appears to be influenced by anticoagulant treatment introduced for VTE, as well as the presence or absence of ongoing anticoagulation at the diagnosis of VTE.PMID:35525202 | DOI:10.1016/j.thromres.2022.04.016
Source: Atherosclerosis - May 7, 2022 Category: Cardiology Authors: Steve Raoul Noumegni Romain Didier Vincent Mansourati C écile Tromeur Emmanuelle Le Moigne Cl ément Hoffmann Bahaa Nasr Jean-Christophe Gentric Marie Guegan Elise Poulhazan Karine Lacut Luc Bressollette Raphael Le Mao Francis Couturaud Source Type: research

De Novo Sphingolipid Biosynthesis in Atherosclerosis
Adv Exp Med Biol. 2022;1372:31-46. doi: 10.1007/978-981-19-0394-6_3.ABSTRACTAtherosclerosis is the formation of fibrofatty lesions in the arterial wall, and this inflammatory state of the artery is the main cause of advanced pathological processes, including myocardial infarction and stroke. Dyslipidemic conditions with excess cholesterol accumulate within the arterial vessel wall and initiate atherogenic processes. Following vascular reaction and lipid accumulation, the vascular wall gradually thickens. Together with the occurrence of local inflammation, early atherosclerotic lesions lead to advanced pathophysiological ev...
Source: Atherosclerosis - May 3, 2022 Category: Cardiology Authors: Tae-Sik Park Shivani Devi Amitesh Sharma Goon-Tae Kim Kyung-Hee Cho Source Type: research

Aging-Related Vascular Inflammation: Giant Cell Arteritis and Neurological Disorders
Front Aging Neurosci. 2022 Apr 12;14:843305. doi: 10.3389/fnagi.2022.843305. eCollection 2022.ABSTRACTAging is characterized by the functional decline of the immune system and constitutes the primary risk factor for infectious diseases, cardiovascular disorders, cancer, and neurodegenerative disorders. Blood vessels are immune-privileged sites and consist of endothelial cells, vascular smooth muscle cells, macrophages, dendritic cells, fibroblasts, and pericytes, among others. Aging also termed senescence inevitably affects blood vessels, making them vulnerable to inflammation. Atherosclerosis causes low-grade inflammation...
Source: Atherosclerosis - May 2, 2022 Category: Cardiology Authors: Ryu Watanabe Motomu Hashimoto Source Type: research

Could "cellular exercise" be the missing ingredient in a healthy life? Diets, caloric restriction, and exercise-induced hormesis
Nutrition. 2022 Feb 7;99-100:111629. doi: 10.1016/j.nut.2022.111629. Online ahead of print.ABSTRACTOvernutrition is a poor dietary habit that has been correlated with increased health risks, especially in the developed world. This leads to an imbalance between energy storage and energy breakdown. Many biochemical processes involving hormones are involved in conveying the excess of energy into pathologic states, mainly atherosclerosis, hypertension, cardiovascular diseases, and diabetes. Diverse modalities of regular exercise have been shown to be beneficial, to varying extents, in overcoming the overnutrition comorbidities...
Source: Atherosclerosis - April 30, 2022 Category: Cardiology Authors: Iv John L Pinches Yiuing L Pinches John O Johnson Natasha C Haddad Myriam G Boueri Luc M Oke Georges E Haddad Source Type: research