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Specialty: Laboratory Medicine
Cancer: Cancer
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Total 267 results found since Jan 2013.
Transcription Activation of Rab8A by PEA3 Augments Progression of Esophagus Cancer by Activating the Wnt/ < em > β < /em > -Catenin Signaling Pathway
CONCLUSIONS: The data showed that Rab8A was transcriptionally regulated by PEA3 and promoted the malignant behaviors of esophagus cancer cells by activating the Wnt/β-catenin pathway. The above results indicated that Rab8A may be considered as a promising biomarker for diagnosis and precision treatment in esophagus cancer.PMID:36815135 | PMC:PMC9940983 | DOI:10.1155/2023/8143581
Source: Disease Markers - February 23, 2023 Category: Laboratory Medicine Authors: Shusheng Cai Xiumei Liu Weiran Gao Lianhua Ye Qiming Zhong Xin Zhang Source Type: research
Systematic Pan-Cancer Analysis and Experimental Verification Identify FOXA1 as an Immunological and Prognostic Biomarker in Epithelial Ovarian Cancer
CONCLUSIONS: Our results predict and validate the function of FOXA1 in promoting EMT and the progression of disease in EOC. Targeting FOXA1 may improve the sensitivity of EOC treatment.PMID:36393971 | PMC:PMC9646314 | DOI:10.1155/2022/9328972
Source: Disease Markers - November 17, 2022 Category: Laboratory Medicine Authors: Kai Wang Chenan Guan Junhui Yu Xing Chen Xianwen Shang Shuangshuang Mei Xingjun Feng Lingzhi Zheng Source Type: research
ZNF574 Promotes Ovarian Cancer Cell Proliferation and Migration through Regulating AKT and AMPK Signaling Pathways
CONCLUSION: These results indicated that ZNF574 may function as an oncogene in ovarian cancer through regulation of the AKT and AMPK signaling pathways. Furthermore, ZNF574 may be a prognostic indicator and therapeutic target for ovarian cancer.PMID:36197766
Source: Annals of Clinical and Laboratory Science - October 5, 2022 Category: Laboratory Medicine Authors: Jingjing Zhang Xiaoli Wu Li Huang Source Type: research
ATF4/MYC Regulates MTHFD2 to Promote NSCLC Progression by Mediating Redox Homeostasis
CONCLUSIONS: ATF4 promoted high expression of MTHFD2 in NSCLC dependent on MYC.PMID:36051358 | PMC:PMC9425107 | DOI:10.1155/2022/7527996
Source: Disease Markers - September 2, 2022 Category: Laboratory Medicine Authors: Yixing Gao Lan Feng Luping Zhang Jianhui Geng Erlong Zhang Source Type: research
