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Total 408 results found since Jan 2013.
Effect of cocoa flavanol supplementation for prevention of cardiovascular disease events: The COSMOS randomized clinical trial
CONCLUSION: Cocoa extract supplementation did not significantly reduce total cardiovascular events among older adults but reduced CVD death by 27%. Potential reductions in total cardiovascular events were supported in per-protocol analyses. Additional research is warranted to clarify whether cocoa extract may reduce clinical cardiovascular events.PMID:35294962 | DOI:10.1093/ajcn/nqac055
Source: Am J Clin Nutr - March 16, 2022 Category: Nutrition Authors: Howard D Sesso JoAnn E Manson Aaron K Aragaki Pamela M Rist Lisa G Johnson Georgina Friedenberg Trisha Copeland Allison Clar Samia Mora M Vinayaga Moorthy Ara Sarkissian William R Carrick Garnet L Anderson COSMOS Research Group Source Type: research
Hippocrates Was Right: Now What? Water As a Part of Healthy Aging
Background: Aging is defined as the progressive organism change leading to debility, disease, and death [1]. We know that as we age, our risk increases for diseases such as diabetes, cancer, and chronic kidney disease, and many of our homeostatic processes change as well, such as cell signaling, metabolism, and proteostasis [2]. The data clearly show that water intake decreases with aging, especially after age 60 years [3]. However, the question becomes “Do we drink less because we age, or do we age because we drink less?” (Fig. 1).Summary: There are data to support both directions of this hypothesis. One example suppo...
Source: Annals of Nutrition and Metabolism - February 28, 2022 Category: Nutrition Source Type: research
Causal relationship from coffee consumption to diseases and mortality: a review of observational and Mendelian randomization studies including cardiometabolic diseases, cancer, gallstones and other diseases
ConclusionHigh coffee consumption is associated with low risk of mortality, cardiometabolic diseases, some cancers and gallstones in observational studies, with no evidence to support causality from Mendelian randomization studies for most diseases except gallstones.
Source: European Journal of Nutrition - February 27, 2022 Category: Nutrition Source Type: research
Vitamin D supplementation and prevention of cardiovascular disease and cancer in the Finnish Vitamin D Trial-a randomized controlled trial
CONCLUSIONS: Vitamin D3 supplementation did not lower the incidence of major CVD events or invasive cancer among older adults, possibly due to sufficient vitamin D status in most participants at baseline. Clinical Trial Registry number: ClinicalTrials.gov: NCT01463813, https://clinicaltrials.gov/ct2/show/NCT01463813.PMID:34982819 | DOI:10.1093/ajcn/nqab419
Source: The American Journal of Clinical Nutrition - January 4, 2022 Category: Nutrition Authors: Jyrki K Virtanen Tarja Nurmi Antti Aro Elizabeth R Bertone-Johnson Elina Hypp önen Heikki Kr öger Christel Lamberg-Allardt JoAnn E Manson Jaakko Mursu Pekka M äntyselkä Sakari Suominen Matti Uusitupa Ari Voutilainen Tomi-Pekka Tuomainen Sari Hantunen Source Type: research
Lycopene and Chrysin through Mitigation of Neuroinflammation and Oxidative Stress Exerted Antidepressant Effects in Clonidine-Induced Depression-like Behavior in Rats
J Diet Suppl. 2021 Oct 11:1-20. doi: 10.1080/19390211.2021.1988797. Online ahead of print.ABSTRACTDepression is a severely debilitating psychiatric disorder that influences more than 15% of the population worldwide. It has been demonstrated that it is associated with a high risk of developing other diseases such as cardiovascular diseases, diabetes, stroke, epilepsy, and cancer. The current study examines the possibility of chrysin and lycopene having an antidepressant effect in a rat model of depression induced by clonidine, as well as the mechanisms underlying this effect, including the role of neuroinflammation and oxid...
Source: Journal of Dietary Supplements - October 11, 2021 Category: Nutrition Authors: Ekram Nemr Abd Al Haleem Hebatalla I Ahmed Reem N El-Naga Source Type: research
