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Cancer: Gastric (Stomach) Cancer
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Artificial intelligence technologies empowering identification of novel diagnostic molecular markers in gastric cancer
Indian J Pathol Microbiol. 2021 Jun;64(Supplement):S63-S68. doi: 10.4103/IJPM.IJPM_950_20.ABSTRACTIn recent clinical practice the molecular diagnostics have been significantly empowered and upgraded by the use of Artificial Intelligence and its assisted technologies. The use of Machine leaning and Deep Learning Neural network architectures have brought in a new dimension in clinical oncological research and development. These algorithm based software system with enhanced digital image analysis have emerged into a new branch of digital pathology and contributed immensely towards precision medicine and personal diagnostics. ...
Source: Indian Journal of Pathology and Microbiology - June 17, 2021 Category: Pathology Authors: Ishan Pandey Vatsala Misra Aprajita T Pandey Pramod W Ramteke Ranjan Agrawal Source Type: research
Influence of molecular pathology on oncological surgery of tumors of the upper gastrointestinal tract
CONCLUSION: To date, only a few targeted therapeutic options have been successfully transferred into daily routine derived from the genetic characterization of the three tumor entities. These include selective ERBB2 inhibition, immunotherapy using PD-L1 inhibition or combined blockade of ERBB2/VEGF.PMID:34287671 | DOI:10.1007/s00104-021-01466-x
Source: Der Chirurg - July 21, 2021 Category: Surgery Authors: Patrick S Plum Alexander Quaas Hakan Alakus Christiane J Bruns Source Type: research
Towards a Treatment Sequencing Strategy: A Systematic Review of Treatment Regimens in Advanced Gastric Cancer/Gastroesophageal Junction Adenocarcinoma
CONCLUSION: For advanced G/GEA, review of trial results from 2009-2019 support 1L therapy with platinum and fluoropyrimidine and sequencing with taxanes or irinotecan in combination with biologics as effective 2L options. Escalating to a triplet may add some efficacy at the expense of added toxicity.IMPLICATIONS FOR PRACTICE: The rapidly changing treatment landscape for advanced gastric cancer includes increasing options for refractory disease. With multiple first-line platinum-based regimens, identification of those with the best benefit-to-risk ratio may provide guidance on treatment sequencing strategies. Herein, we pre...
Source: The Oncologist - July 21, 2021 Category: Cancer & Oncology Authors: Daniel V Catenacci Joseph Chao Kei Muro Salah Eddin Al-Batran Samuel J Klempner Zev A Wainberg Manish A Shah Sun Young Rha Atsushi Ohtsu Astra M Liepa Holly Knoderer Anindya Chatterjee Eric Van Cutsem Source Type: research
Artificial intelligence technologies empowering identification of novel diagnostic molecular markers in gastric cancer
Indian J Pathol Microbiol. 2021 Jun;64(Supplement):S63-S68. doi: 10.4103/IJPM.IJPM_950_20.ABSTRACTIn recent clinical practice the molecular diagnostics have been significantly empowered and upgraded by the use of Artificial Intelligence and its assisted technologies. The use of Machine leaning and Deep Learning Neural network architectures have brought in a new dimension in clinical oncological research and development. These algorithm based software system with enhanced digital image analysis have emerged into a new branch of digital pathology and contributed immensely towards precision medicine and personal diagnostics. ...
Source: Indian Journal of Pathology and Microbiology - June 17, 2021 Category: Pathology Authors: Ishan Pandey Vatsala Misra Aprajita T Pandey Pramod W Ramteke Ranjan Agrawal Source Type: research
Influence of molecular pathology on oncological surgery of tumors of the upper gastrointestinal tract
CONCLUSION: To date, only a few targeted therapeutic options have been successfully transferred into daily routine derived from the genetic characterization of the three tumor entities. These include selective ERBB2 inhibition, immunotherapy using PD-L1 inhibition or combined blockade of ERBB2/VEGF.PMID:34287671 | DOI:10.1007/s00104-021-01466-x
Source: Der Chirurg - July 21, 2021 Category: Surgery Authors: Patrick S Plum Alexander Quaas Hakan Alakus Christiane J Bruns Source Type: research
Towards a Treatment Sequencing Strategy: A Systematic Review of Treatment Regimens in Advanced Gastric Cancer/Gastroesophageal Junction Adenocarcinoma
CONCLUSION: For advanced G/GEA, review of trial results from 2009-2019 support 1L therapy with platinum and fluoropyrimidine and sequencing with taxanes or irinotecan in combination with biologics as effective 2L options. Escalating to a triplet may add some efficacy at the expense of added toxicity.IMPLICATIONS FOR PRACTICE: The rapidly changing treatment landscape for advanced gastric cancer includes increasing options for refractory disease. With multiple first-line platinum-based regimens, identification of those with the best benefit-to-risk ratio may provide guidance on treatment sequencing strategies. Herein, we pre...
Source: The Oncologist - July 21, 2021 Category: Cancer & Oncology Authors: Daniel V Catenacci Joseph Chao Kei Muro Salah Eddin Al-Batran Samuel J Klempner Zev A Wainberg Manish A Shah Sun Young Rha Atsushi Ohtsu Astra M Liepa Holly Knoderer Anindya Chatterjee Eric Van Cutsem Source Type: research
Artificial intelligence technologies empowering identification of novel diagnostic molecular markers in gastric cancer
Indian J Pathol Microbiol. 2021 Jun;64(Supplement):S63-S68. doi: 10.4103/IJPM.IJPM_950_20.ABSTRACTIn recent clinical practice the molecular diagnostics have been significantly empowered and upgraded by the use of Artificial Intelligence and its assisted technologies. The use of Machine leaning and Deep Learning Neural network architectures have brought in a new dimension in clinical oncological research and development. These algorithm based software system with enhanced digital image analysis have emerged into a new branch of digital pathology and contributed immensely towards precision medicine and personal diagnostics. ...
Source: Indian Journal of Pathology and Microbiology - June 17, 2021 Category: Pathology Authors: Ishan Pandey Vatsala Misra Aprajita T Pandey Pramod W Ramteke Ranjan Agrawal Source Type: research
Towards a Treatment Sequencing Strategy: A Systematic Review of Treatment Regimens in Advanced Gastric Cancer/Gastroesophageal Junction Adenocarcinoma
CONCLUSION: For advanced G/GEA, review of trial results from 2009-2019 support 1L therapy with platinum and fluoropyrimidine and sequencing with taxanes or irinotecan in combination with biologics as effective 2L options. Escalating to a triplet may add some efficacy at the expense of added toxicity.IMPLICATIONS FOR PRACTICE: The rapidly changing treatment landscape for advanced gastric cancer includes increasing options for refractory disease. With multiple first-line platinum-based regimens, identification of those with the best benefit-to-risk ratio may provide guidance on treatment sequencing strategies. Herein, we pre...
Source: The Oncologist - July 21, 2021 Category: Cancer & Oncology Authors: Daniel V Catenacci Joseph Chao Kei Muro Salah Eddin Al-Batran Samuel J Klempner Zev A Wainberg Manish A Shah Sun Young Rha Atsushi Ohtsu Astra M Liepa Holly Knoderer Anindya Chatterjee Eric Van Cutsem Source Type: research
Artificial intelligence technologies empowering identification of novel diagnostic molecular markers in gastric cancer
Indian J Pathol Microbiol. 2021 Jun;64(Supplement):S63-S68. doi: 10.4103/IJPM.IJPM_950_20.ABSTRACTIn recent clinical practice the molecular diagnostics have been significantly empowered and upgraded by the use of Artificial Intelligence and its assisted technologies. The use of Machine leaning and Deep Learning Neural network architectures have brought in a new dimension in clinical oncological research and development. These algorithm based software system with enhanced digital image analysis have emerged into a new branch of digital pathology and contributed immensely towards precision medicine and personal diagnostics. ...
Source: Indian Journal of Pathology and Microbiology - June 17, 2021 Category: Pathology Authors: Ishan Pandey Vatsala Misra Aprajita T Pandey Pramod W Ramteke Ranjan Agrawal Source Type: research
A meta-analysis of robotic gastrectomy versus open gastrectomy in gastric cancer treatment
Asian J Surg. 2021 Aug 6:S1015-9584(21)00485-1. doi: 10.1016/j.asjsur.2021.07.069. Online ahead of print.ABSTRACTRobotic gastrectomy (RG) shows potential as an alternative to open gastrectomy (OG), the gold standard in the surgical management of gastric cancer (GC). This meta-analysis was conducted to compare the short-term efficacy and safety of RG versus OG for GC.A systematic literature search was conducted on RG with OG for GC in randomized and semi-randomized controlled trials and observational studies. Published materials and conference papers in English and trace references included in the literature were manually s...
Source: Asian Journal of Surgery - August 9, 2021 Category: Surgery Authors: Lei Chen Qian Wang Yu Liu Yonghong Wang Yaping Li Jie Dan Jian Wang Source Type: research
