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A Case Report of Herpes Zoster Ophthalmicus and Meningitis After COVID-19 Vaccination
J Korean Med Sci. 2022 May 23;37(20):e165. doi: 10.3346/jkms.2022.37.e165.ABSTRACTThere are several reports that herpes zoster characterized by reactivation of varicella zoster virus (VZV) following coronavirus disease 2019 (COVID-19) vaccines can occur. Herein, we report VZV meningitis, herpes zoster ophthalmicus (HZO), and late neurotrophic keratitis after receiving a second dose of messenger RNA (mRNA) COVID-19 vaccine. A 74-year-old man developed a vesicular skin rash on the forehead, scalp, nose, and left upper eyelid with a severe headache. Five days earlier, he received a second dose of the BNT162b2 mRNA vaccine on ...
Source: Journal of Korean Medical Science - May 24, 2022 Category: Biomedical Science Authors: In-Cheon You Min Ahn Nam-Chun Cho Source Type: research

A Case Report of Varicella Zoster Meningitis as Co-Infection With Breakthrough COVID-19 in an Immunocompetent Patient
J Korean Med Sci. 2022 Feb 28;37(8):e61. doi: 10.3346/jkms.2022.37.e61.ABSTRACTThere are several previous reports that infection or reactivation of varicella zoster virus (VZV) can occur after coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Herein, we report a rare case of VZV meningitis in breakthrough COVID-19. An 18-years-old male visited the emergency room, presenting with a headache and fever of up to 38.4°C for 5 days. He received the second dose of BNT162b2 mRNA SARS-CoV-2 vaccine 7 weeks prior to symptom onset. The symptoms persisted with headac...
Source: Journal of Korean Medical Science - February 28, 2022 Category: Biomedical Science Authors: SeungHoon Yun Jinyong Kim Hye-Rim Shin Source Type: research

BCG vaccination history associates with decreased SARS-CoV-2 seroprevalence across a diverse cohort of health care workers
CONCLUSIONS A history of BCG vaccination was associated with a decrease in the seroprevalence of anti–SARS-CoV-2 IgG and a lower number of participants who self-reported experiencing COVID-19–related clinical symptoms in this cohort of HCWs. Therefore, large randomized, prospective clinical trials of BCG vaccination are urgently needed to confirm whether BCG vaccination can confer a protective effect against SARS-CoV-2 infection.
Source: Journal of Clinical Investigation - January 20, 2021 Category: Biomedical Science Authors: Magali Noval Rivas, Joseph E. Ebinger, Min Wu, Nancy Sun, Jonathan Braun, Kimia Sobhani, Jennifer E. Van Eyk, Susan Cheng, Moshe Arditi Source Type: research