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Prevention and treatment of upper respiratory diseases in the pandemic COVID-19 era
J Biol Regul Homeost Agents. 2021 Jan-Feb;35(1 Suppl. 2):3-8. doi: 10.23812/21-1supp2-2.ABSTRACTIn the pandemic coronavirus disease 2019 (COVID-19) era, the need to use preventive-curative treatments is compelling. A series of non-pharmacological compounds, including oligo-elements, vitamins, nutraceuticals, and bacteriotherapy, might affect the risk of COVID-19, both reinforcing the immune system and improving the inflammation resolution during respiratory infections. Non-pharmacological remedies are very popular and usually have no relevant side effects. Bacterial and natural products may potentiate the immune system aga...
Source: Journal of Biological Regulators and Homeostatic Agents - May 13, 2021 Category: Biomedical Science Authors: D Passali L M Bellussi F M Passali R De Hoyos S Di Girolamo G Ciprandi Source Type: research

Non-pharmacological remedies for upper respiratory diseases in the pandemic COVID-19 era.
Authors: Ciprandi G, Aragona SE Abstract In the pandemic coronavirus disease 2019 (COVID-19) era, the need to use preventive-curative treatments is compelling. A series of non-pharmacological compounds, including supplements (oligoelements and vitamins), probiotics, and nutraceuticals, might affect the risk of COVID-19 or reducing clinical severity. Non-pharmacological remedies are easily available and usually have no relevant side effects. There is evidence that bacterial and molecular substances may potentiate the immune system against respiratory viruses. Moreover, these compounds might exert essential anti-infl...
Source: Journal of Biological Regulators and Homeostatic Agents - January 13, 2021 Category: Biomedical Science Tags: J Biol Regul Homeost Agents Source Type: research

Commentary: Could iron chelators prove to be useful as an adjunct to COVID-19 Treatment Regimens?
The pandemic of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a significant threat to global health. Currently, no specific prophylactic and therapeutic treatment is available. No evidence from randomized clinical trials (RCTs) that a treatment may ameliorate the clinical outcome of patients with COVID-19 exists with the only exception of preliminary evidence from remdesivir trials. Here, we present evidence from the literature and a compelling hypothesis on the potential immunomodulatory, iron chelating and anti-oxidant effects of iron chelators in the treatment of COVID-19 and its complications.
Source: Metabolism - Clinical and Experimental - May 9, 2020 Category: Biomedical Science Authors: Maria Dalamaga, Irene Karampela, Christos S. Mantzoros Source Type: research

19 treatment regimens?
The pandemic of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a significant threat to global health. Currently, no specific prophylactic and therapeutic treatment is available. No evidence from randomized clinical trials (RCTs) that a treatment may ameliorate the clinical outcome of patients with COVID-19 exists with the only exception of preliminary evidence from remdesivir trials. Here, we present evidence from the literature and a compelling hypothesis on the potential immunomodulatory, iron chelating and anti-oxidant effects of iron chelators in the treatment of COVID-19 and its complications.
Source: Metabolism - Clinical and Experimental - May 9, 2020 Category: Biomedical Science Authors: Maria Dalamaga, Irene Karampela, Christos S. Mantzoros Source Type: research