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Why efforts to make better, more universal coronavirus vaccines are struggling
There’s a new call from the White House to develop vaccines that might protect against future SARS-CoV-2 mutants or even unknown coronaviruses. “The vaccines we have are terrific, but we can do better than terrific,” Ashish Jha, White House COVID-19 response coordinator, said at a vaccine summit yesterday that gathered researchers, companies, and government officials. “Ultimately, we need vaccines that can protect us no matter what Mother Nature throws at us.” But no specific funding request to Congress was revealed at the summit, or any concrete plans, so vaccine developers and the public shouldn’t expect...
Source: Science of Aging Knowledge Environment - July 27, 2022 Category: Geriatrics Source Type: research

Quantitative analysis of RNA by HPLC and evaluation of RT-dPCR for coronavirus RNA quantification
In this study, we developed HPLC method combined with enzymatic digestion of RNA to nucleotides for quantification of RNA without RT process. This method was metrologically traceable to four nuceloside monophosphate (NMP) Certification Reference Materials of National Institute of Metrology, China (NIMC) for insurance of accuracy. The established method was used to evaluate the reverse transcription digital polymerase chain reaction (RT-dPCR) of three target genes of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) RNA, including open reading frame 1ab (ORF1ab), nucleocapsid protein (N) and envelope protein (E) gene....
Source: Talanta - March 28, 2021 Category: Chemistry Authors: Chunyan Niu Lianhua Dong Yunhua Gao Yongzhuo Zhang Xia Wang Jing Wang Source Type: research

COMMENTARY: The Sinatra Doctrine Confronts a Global Consensus
A photo-collage. Credit: Peter Costantini.By Peter CostantiniSEATTLE, Oct 23 2020 (IPS) By late September, the COVID-19 pandemic in the United States had claimed 200,000 lives. That’s equivalent to a slightly higher toll than the 418,500 United States deaths in World War II, adjusted for relative population and duration. [See note below.] With four percent of the world’s population, the U.S. has suffered 20 percent of global COVID-19 deaths. Tragically, most of these deaths need never have happened. They were caused primarily by the public-health equivalent of friendly fire: massive malpractice and deception by the Don...
Source: IPS Inter Press Service - Health - October 23, 2020 Category: International Medicine & Public Health Authors: Peter Costantini Tags: Global Geopolitics Global Governance Headlines Health TerraViva United Nations Source Type: news

Strengthening China's Public Health Response System: From SARS to COVID-19.
Abstract Today, the world is experiencing a pandemic caused by a novel coronavirus. COVID-19 is the third disease from a coronavirus to cause a global outbreak, after severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), and the second that emerged from China. During the 17 years between the SARS and the COVID-19 outbreaks, China has quadrupled its share of the world economy, lifted hundreds of millions of people out of poverty, and established a national health insurance system covering 95% of its 1.4 billion people. Will China's public heath response to a coronavirus epidemic be d...
Source: Am J Public Health - March 25, 2020 Category: International Medicine & Public Health Authors: Bouey J Tags: Am J Public Health Source Type: research

Is there any good news about the coronavirus pandemic?
In the midst of the fear, worry, and uncertainty surrounding the coronavirus pandemic, each day seems to bring news that’s worse than the day before. The cause for concern is justified. But, as in most major disasters, tragedies, and public health threats, there are reasons for hope, and even optimism. They may be hard to see, even if you’re a “cup-half-full” or “it could always be worse” type of person. But they are there. Here are a few. The good news about the coronavirus pandemic Most people with COVID-19 recover. Estimates now suggest that 99% of people infected with the virus that causes COVID-19 will re...
Source: Harvard Health Blog - March 19, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Health Infectious diseases Mental Health Relationships Source Type: blogs

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