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Fight Aging! Newsletter, November 28th 2022
This study explored whether determining the gain or loss of specific taxa represent a more precise metric of healthy/unhealthy aging than summary microbiome statistics, such as diversity and uniqueness. We analyzed microbiome diversity and four measures of microbiome uniqueness in 21,000 gut microbiomes for their relationship with aging and health. We show that diversity and uniqueness measures are not synonymous; uniqueness is not a uniformly desirable feature of the aging microbiome, nor is it an accurate biomarker of healthy aging. Different measures of uniqueness show different associations with diversity and with mark...
Source: Fight Aging! - November 27, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, August 1st 2022
In this study, we used the recently released Infinium Mouse Methylation BeadChip to compare such epigenetic modifications in C57BL/6 (B6) and DBA/2J (DBA) mice. We observed marked differences in age-associated DNA methylation in these commonly used inbred mouse strains, indicating that epigenetic clocks for one strain cannot be simply applied to other strains without further verification. Interestingly, the CpGs with highest age-correlation were still overlapping in B6 and DBA mice and included the genes Hsf4, Prima1, Aspa, and Wnt3a. Furthermore, Hsf4, Aspa, and Wnt3a revealed highly significant age-associated DNA methyla...
Source: Fight Aging! - July 31, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

NIDCR's Winter 2021 E-Newsletter
Having trouble viewing this email? View it as a Web page. NIDCR's Winter 2021 E-Newsletter In this issue: NIDCR News Funding Opportunities & Related Notices NIH/HHS News Subscribe to NIDCR News Science Advances   NIDCR News NIDCR Major Announcement: Save the Date! Mark your calendar for Tuesday, December 21, at 1pm for a major webcast announcement from NIDCR. Look for log-in instructions, coming in a separate NIDCR email next week. Jennifer Webster-Cyriaque Joins NIDCR as Deputy Director NIDCR welcomed Jennifer Webster-Cyriaqu...
Source: NIDCR Science News - December 8, 2021 Category: Dentistry Source Type: news

NIDCR's Fall 2021 E-Newsletter
Having trouble viewing this email? View it as a Web page. NIDCR's Fall 2021 E-Newsletter In this issue: NIDCR News Funding Opportunities & Related Notices NIH/HHS News Subscribe to NICDR News Science Advances   NIDCR News 5 Q&As About “Oral Health in America: Advances and Challenges” NIDCR issued a brief Q&A regarding details of the forthcoming report Oral Health in America: Advances and Challenges, which will be published in Fall 2021. This comprehensive report will examine improvements in oral health over the past two decades,...
Source: NIDCR Science News - September 1, 2021 Category: Dentistry Source Type: news

World pledges $4B in push to repair COVID's education damage
International governments and companies have pledged more than $4 billion to educate 175 million children around the world and prevent a generation’s chances being blighted by the coronavirus pandemic
Source: ABC News: Health - July 29, 2021 Category: Consumer Health News Tags: Health Source Type: news

Fight Aging! Newsletter, March 15th 2021
In conclusion, PLG attenuates high calcium/phosphate-induced vascular calcification by upregulating P53/PTEN signaling in VSMCs. Tsimane and Moseten Hunter-Gatherers Exhibit Minimal Levels of Atrial Fibrillation https://www.fightaging.org/archives/2021/03/tsimane-and-moseten-hunter-gatherers-exhibit-minimal-levels-of-atrial-fibrillation/ Epidemiological data for the Tsimane and Moseten populations in Bolivia shows that they suffer very little cardiovascular disease in later life, despite a presumably greater lifetime burden of infectious disease (and consequent inflammation) than is the case for people i...
Source: Fight Aging! - March 14, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

International Women ’s Day, 2021The World Not Only Needs Women Leaders – It Needs Feminist Leaders
Audrey Azoulay, Director-General of UNESCOBy Audrey Azoulay and Katrín JakobsdóttirPARIS and REYKJAVIK, Mar 5 2021 (IPS) International Women’s Day pays tribute to the achievements of women worldwide and reminds us what still needs to be done for full gender equality. In 2021, we are taking stock of the many ways in which COVID-19 has disproportionately affected women and girls around the world. The pandemic has created a new landscape. Although women have played a key role in responding to the crisis, gender inequalities have widened across the board. In education, 767 million women and girls were impacted by scho...
Source: IPS Inter Press Service - Health - March 5, 2021 Category: International Medicine & Public Health Authors: Audrey Azoulay and Katrin Jakobsdottir Tags: Civil Society Crime & Justice Economy & Trade Education Featured Gender Gender Violence Global Headlines Health Human Rights Humanitarian Emergencies Inequity Labour TerraViva United Nations Women & Economy Women in Politic Source Type: news

Fight Aging! Newsletter, October 5th 2020
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - October 4, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Changes in Alcohol Use Habits in the General Population, during the COVID-19 Lockdown in Greece
On March 11, 2020, WHO declared COVID-19 a pandemic. Considering the risk of rapid spread, Greece imposed a nationwide lockdown early in its coronavirus outbreak, including movement restriction, limited public transportations, suspension of educational institutions as well as closure of cafes, bars, restaurants, museums, shopping centers and sports facilities. Only essential public services such as hospitals, police and fire stations were excluded from the general lockdown along with supermarkets, supply food chain stores, caterers, pharmacies, gas stations, car repair shops, mini markets and convenience stores, cafes and ...
Source: Alcohol and Alcoholism - September 22, 2020 Category: Addiction Source Type: research

Fight Aging! Newsletter, August 24th 2020
We report that electrical stimulation (ES) stimulation of post-stroke aged rats led to an improved functional recovery of spatial long-term memory (T-maze), but not on the rotating pole or the inclined plane, both tests requiring complex sensorimotor skills. Surprisingly, ES had a detrimental effect on the asymmetric sensorimotor deficit. Histologically, there was a robust increase in the number of doublecortin-positive cells in the dentate gyrus and SVZ of the infarcted hemisphere and the presence of a considerable number of neurons expressing tubulin beta III in the infarcted area. Among the genes that were unique...
Source: Fight Aging! - August 23, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Aging Research Should be Far More of a Priority than is Presently the Case
For our species, aging is by far the greatest single cause of suffering and death. It is presently inevitable, affects everyone, and produces a drawn out decline of pain and disability, leading to a horrible death through progressive organ failure of one sort or another. The integrity of the mind is consumed along with the vitality of the body. Aging is the cause of death of 90% or more of the people who live in wealthier regions of the world, and the majority of those even in the poorest regions. More than 100,000 lives every day are lost to aging, and hundreds of millions more are suffering on their way to that fate. ...
Source: Fight Aging! - August 21, 2020 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs

Surgical Protocol in a West China Day Surgery Center During the COVID-19 Pandemic: Practice and Experience.
Conclusions. Using scientific and well-designed protocols, day surgery can ensure quality surgical care with while ensuring medical safety during the COVID-19 outbreak. These protocols may also be applied to other surgical departments in China. PMID: 32795165 [PubMed - as supplied by publisher]
Source: Surgical Innovation - August 13, 2020 Category: Surgery Authors: Jiang L, Ma H Tags: Surg Innov Source Type: research

Care home death figures a ‘national scandal’, says UNISON
Responding to data published today (Tuesday) by the Office for National Statistics which include more than 200 Covid-related deaths in care homes, UNISON general secretary Dave Prentis said: “These figures are nothing short of a national scandal. Elderly and vulnerable residents face a death sentence because staff lack personal protective equipment (PPE). “Care workers report that protective kit is still being locked away, having to make single-use masks last all week and being told they don’t need masks because residents aren’t displaying virus symptoms. Many talk too of there not being enough essential...
Source: UNISON Health care news - April 14, 2020 Category: UK Health Authors: Sophie Goodchild Tags: News Press release care staff Covid deaths PPE Source Type: news

NIDCR's Spring 2020 E-Newsletter
Having trouble viewing this email? View it as a Web page. NIDCR's Spring 2020 E-Newsletter In this issue: NIDCR News Funding Opportunities NIH/HHS News Funding Notices Science Advances Subscribe to NICDR News Grantee News   NIDCR News CDC’s COVID-19 Guidance for Dental Settings  Dental health care personnel can find COVID-19-related information on the CDC’s Division of Oral Health website, which offers guidance and resources for clinics and health care facilities and recommendations for respondi...
Source: NIDCR Science News - March 27, 2020 Category: Dentistry Source Type: news