Bad Wegener's and Lung RT
69 yo man with COPD and ILD with Wegeners Granulomatosis (GPA) on 2-3L O2 at rest and 3-4L on exertion gets rituxan infusions and on chronic steroids for the GPA had incidentally found 3.5 cm perihilar mass that is touching the aorta from about 2-5 o'clock. Biopsy positive for squamous cell carcinoma. Staged T4N0. Lung function is bad but sounds like he's been stable for over a year since starting rituxan in additionto the chronic steroids. Was just referred to us in RT and referred to med...
Read more (Source: Student Doctor Network)
Source: Student Doctor Network - April 12, 2023 Category: Universities & Medical Training Authors: Haybrant Tags: Radiation Oncology Source Type: forums
Rituximab and risk of HBV re-activation
[you guys probably give way more rituximab than I do.]
You know how you're supposed to get a hepatitis panel before starting rituximab, so what if the panel is positive for the inactive chronic charier state of HBV? (+HBsAg , +HBcAb , but undetectable viral load, normal liver enzymes).
Could you still give the rituximab? Or is even the inactive carrier state of HBV (negative PCR, negative LAEs) a contraindication? (Source: Student Doctor Network)
Source: Student Doctor Network - May 16, 2021 Category: Universities & Medical Training Authors: DrMetal Tags: Hematology / Oncology Source Type: forums
Respiratory Alkalosis
65 year old patient who was dignosed with primary B cell testicular lymphoma which had gone just to his brain ( frontal lobe) last year in August. He was given chemo which removed his tumor, he then has been given 2 rituximab session uptil now. Recently 3 or 4 days back he started hyperventilating and now has been dignosed with partially compensated resp alkalosis. His PH is 7.5 his Co2 and HCO3 are both 9. His cretinine is slightly elevated too. His lungs are clear. Plz help! (Source: Doc2Doc BMJ Cardiology)
Source: Doc2Doc BMJ Cardiology - May 12, 2014 Category: Cardiology Authors: princess58 Source Type: forums
