Safety and effectiveness of standardized exercise training in patients with pulmonary hypertension associated with heart failure with preserved ejection fraction (TRAIN-HFpEF-PH): study protocol for a randomized controlled multicenter trial
This study is designed to investigate whether a standardized low-intensity exercise and respiratory training program is safe and may improve exercise capacity, QoL, hemodynamics, diastolic function, and biomarkers in patients with HFpEF-PH.MethodsA total of 90 stable patients with HFpEF-PH (World Health Organization functional class II –IV) will be randomized (1:1) to receive a 15-week specialized low-intensity rehabilitation program, including exercise and respiratory therapy and mental gait training, with an in-hospital start, or standard care alone. The primary endpoint of the study is a change in 6-min walk test dist...
Source: Trials - April 19, 2023 Category: Research Source Type: clinical trials

Pulmonary Hypertension Screening in Patients With Interstitial Lung Disease for Earlier Detection
Conditions:   Interstitial Lung Disease;   Pulmonary Hypertension Intervention:   Procedure: Right heart catheterization (RHC) Sponsor:   United Therapeutics Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 20, 2023 Category: Research Source Type: clinical trials

A Study to Assess Pulsed Inhaled Nitric Oxide in Subjects With Pulmonary Hypertension Associated With Pulmonary Fibrosis
Conditions:   Pulmonary Fibrosis;   Pulmonary Hypertension Interventions:   Combination Product: INOpulse®;   Combination Product: Placebo;   Combination Product: Long Term Follow Up Sponsor:   Bellerophon Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2023 Category: Research Source Type: clinical trials